Synthesis 2005(1): 25-27  
DOI: 10.1055/s-2004-834935
SHORTPAPER
© Georg Thieme Verlag Stuttgart · New York

An Expeditious Synthesis of 2,4-Disubstituted 2-Imidazolin-5-ones

Said Oumouch, Maryline Bourotte, Martine Schmitt*, Jean-Jacques Bourguignon
Laboratoire de Pharmacochimie de la Communication Cellulaire, UMR 7081 CNRS/ULP, Université Louis Pasteur, Faculté de Pharmacie, 74 route du Rhin, 67401 Illkirch-Graffenstaden, France
Fax: +33(3)90244310; e-Mail: schmitt@pharma.u-strasbg.fr;
Further Information

Publication History

Received 19 July 2004
Publication Date:
03 December 2004 (online)

Abstract

2-Thiomethylimidazolin-5-one undergoes efficient palladium-catalyzed cross-coupling with boronic acids and organostannanes mediated by copper(I) thiophene-2-carboxylate.