Planta Med 2004; 70(11): 1090-1092
DOI: 10.1055/s-2004-832654
Letter
© Georg Thieme Verlag KG Stuttgart · New York

Antifungal Activities of Essential Oils from Thymus quinquecostatus and T. magnus

Seungwon Shin1 , Ji-Hyun Kim1
  • 1College of Pharmacy, Duksung Women's University, Seoul, Korea
Further Information

Publication History

Received: March 19, 2004

Accepted: June 4, 2004

Publication Date:
18 November 2004 (online)

Abstract

The antifungal activities of essential oils from Thymus quinquecostatus and T. magnus, which are species native to Korea, were evaluated against seven common pathogenic fungi. Additionally, the effects of the oils together with ketoconazole were tested by the checkerboard titer test. Both of the two Thymus oils showed significant inhibition of the tested fungi, with minimal inhibitor concentrations (MICs) and minimal fungicidal concentrations (MFCs) in the range of 0.04 - 0.39 mg/mL and 0.19 - 0.78 mg/mL, respectively. The two Thymus oils, and thymol as well, exhibited synergism with ketoconazole against Trichophyton rubrum, which showed the highest susceptibility to these oils.

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Prof. Seungwon Shin, Ph. D.

College of Pharmacy

Duksung Women’s University

Ssangmoondong 419

Dobongku

Seoul 132-714

Korea

Phone: +82-2-901-8384

Fax: +82-2-901-8386

Email: swshin@duksung.ac.kr