Z Gastroenterol 2004; 42(10): 1129-1177
DOI: 10.1055/s-2004-813699
Leitlinie

© Karl Demeter Verlag im Georg Thieme Verlag KG Stuttgart · New York

S3-Leitlinienkonferenz „Kolorektales Karzinom” 2004

S3-Guidelines Colorectal Cancer 2004 
  • 1Ruhr-Universität Bochum, Medizinische Universitätsklinik, Knappschaftskrankenhaus
Further Information

Publication History

Publication Date:
27 October 2004 (online)

Im Auftrag der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten mit Unterstützung der Deutschen Krebshilfe - in Zusammenarbeit mit der
Deutschen Krebsgesellschaft
Deutschen Gesellschaft für Hämatologie und Onkologie
Deutschen Gesellschaft für Innere Medizin
Deutschen Gesellschaft für Koloproktologie
Deutschen Gesellschaft für Pathologie
Deutschen Gesellschaft für Radioonkologie
Deutschen Gesellschaft für Viszeralchirurgie
Deutschen Röntgengesellschaft
Deutschen vereinten Gesellschaft für klinische Chemie und Laboratoriumsmedizin e. V.

Leitung: W. Schmiegel, H.-K. Selbmann
Themenkomplex I: Prävention asymptomatische Bevölkerung
Koordinatoren: G. Adler, J. F. Riemann

Themenkomplex II: Screening asymptomatische Bevölkerung
Koordinatoren: U. R. Fölsch, T. Kühlbacher, C. Pox

Themenkomplex III: Risikogruppen
Koordinatoren: P. Propping, T. Sauerbruch

Themenkomplex IV: Durchführung und Polypenmanagement
Koordinatoren: P. Frühmorgen, M. Zeitz

Themenkomplex V: Präoperative Diagnostik und Chirurgie
Koordinatoren: W. Fleig, W. Hohenberger, T. Junginger

Themenkomplex VI: Adjuvante und neoadjuvante Therapie
Koordinatoren: R. Porschen, R. Sauer

Themenkomplex VII: Therapeutisches Vorgehen bei Metastasierung und in der palliativen Situation
Koordinatoren: U. Graeven, H.-J. Schmoll

Themenkomplex VIII: Nachsorge
Koordinator: A. Holstege

Literatur

  • 1 Gastrointestinal Tumor Study Group . Prolongation of the disease-free interval in surgically treated rectal carcinoma.  N Engl J Med. 1985;  312 1465-1472
  • 2 NIH consensus conference . Adjuvant therapy for patients with colon and rectal cancer.  Jama. 1990;  264 1444-1450
  • 3 Gastrointestinal Tumor Study Group . Radiation therapy and fluorouracil with or without semustine for the treatment of patients with surgical adjuvant adenocarcinoma of the rectum.  J Clin Oncol. 1992;  10 549-557
  • 4 International Multicentre Pooled Analysis of Colon Cancer Trials (IMPACT) investigators . Efficacy of adjuvant fluorouracil and folinic acid in colon cancer.  Lancet. 1995;  345 939-944
  • 5 Swedish Rectal Cancer Trial . Improved survival with preoperative radiotherapy in resectable rectal cancer.  N Engl J Med. 1997;  336 980-987
  • 6 International Multicentre Pooled Analysis of B2 Colon Cancer Trials (IMPACT B2) Investigators . Efficacy of adjuvant fluorouracil and folinic acid in B2 colon cancer.  J Clin Oncol. 1999;  17 1356-1363
  • 7 QUASAR Collaborative Group . Comparison of flourouracil with additional levamisole, higher-dose folinic acid, or both, as adjuvant chemotherapy for colorectal cancer: a randomised trial.  Lancet. 2000;  355 1588-1596
  • 8 Colorectal Cancer Collaborative Group . Adjuvant radiotherapy for rectal cancer: a systematic overview of 8,507 patients from 22 randomised trials.  Lancet. 2001;  358 1291-1304
  • 9 Bekanntmachungen der Bundesärztekammer . Richtlinien zur prädiktiven genetischen Diagnostik.  Dt Ärztebl. 2003;  100 A1297-1305
  • 10 Aarnio M, Mecklin J P, Aaltonen L A. et al . Life-time risk of different cancers in hereditary non-polyposis colorectal cancer (HNPCC) syndrome.  Int J Cancer. 1995;  64 430-433
  • 11 Aarnio M, Salovaara R, Aaltonen L A. et al . Features of gastric cancer in hereditary non-polyposis colorectal cancer syndrome.  Int J Cancer. 1997;  74 551-555
  • 12 Aarnio M, Sankila R, Pukkala E. et al . Cancer risk in mutation carriers of DNA-mismatch-repair genes.  Int J Cancer. 1999;  81 214-218
  • 13 Abcarian H, Pearl R K. Simple technique for high ligation of the inferior mesenteric artery and vein.  Dis Colon Rectum. 1991;  34 1138
  • 14 Adam R, Avisar E, Ariche A. et al . Five-year survival following hepatic resection after neoadjuvant therapy for nonresectable colorectal.  Ann Surg Oncol. 2001;  8 347-353
  • 15 Ahlquist D A, McGill D B, Fleming J L. et al . Patterns of occult bleeding in asymptomatic colorectal cancer.  Cancer. 1989;  63 1826-1830
  • 16 Ahlquist D A, Skoletsky J E, Boynton K A. et al . Colorectal cancer screening by detection of altered human DNA in stool: feasibility of a multitarget assay panel.  Gastroenterology. 2000;  119 1219-1227
  • 17 Ahlquist D A, Wieand H S, Moertel C G. et al . Accuracy of fecal occult blood screening for colorectal neoplasia. A prospective study using Hemoccult and HemoQuant tests.  Jama. 1993;  269 1262-1267
  • 18 Ahsan H, Neugut A I, Garbowski G C. et al . Family history of colorectal adenomatous polyps and increased risk for colorectal cancer.  Ann Intern Med. 1998;  128 900-905
  • 19 Akerkar G A, Yee J, Hung R. et al . Patient experience and preferences toward colon cancer screening: a comparison of virtual colonoscopy and conventional colonoscopy.  Gastrointest Endosc. 2001;  54 310-315
  • 20 Aldridge A J, Simson J N. Histological assessment of colorectal adenomas by size. Are polyps less than 10 mm in size clinically important?.  Eur J Surg. 2001;  167 777-781
  • 21 Allison J E, Tekawa I S, Ransom L J. et al . A comparison of fecal occult-blood tests for colorectal-cancer screening.  N Engl J Med. 1996;  334 155-159
  • 22 Almendingen K, Hofstad B, Trygg K. et al . Current diet and colorectal adenomas: a case-control study including different sets of traditionally chosen control groups.  Eur J Cancer Prev. 2001;  10 395-406
  • 23 Almendingen K, Hofstad B, Trygg K. et al . Smoking and colorectal adenomas: a case-control study.  Eur J Cancer Prev. 2000;  9 193-203
  • 24 Almendingen K, Hofstad B, Vatn M H. Does a family history of cancer increase the risk of occurrence, growth, and recurrence of colorectal adenomas?.  Gut. 2003;  52 747-751
  • 25 Ambiru S, Miyazaki M, Ito H. et al . Adjuvant regional chemotherapy after hepatic resection for colorectal metastases.  Br J Surg. 1999;  86 1025-1031
  • 26 American Gastroerological Association . American Gastroenterological Association medical position statement: impact of dietary fiber on colon cancer occurrence. American College of Gastroenterology.  Gastroenterology. 2000;  118 1233-1234
  • 27 Andre T, Boni C, Mounedji-Boudiaf L. et al . Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer.  N Engl J Med. 2004;  350 2343-2351
  • 28 Andreola S, Leo E, Belli F. et al . Distal intramural spread in adenocarcinoma of the lower third of the rectum treated with total rectal resection and coloanal anastomosis.  Dis Colon Rectum. 1997;  40 25-29
  • 29 Andrieu N, Launoy G, Guillois R. et al . Familial relative risk of colorectal cancer: a population-based study.  Eur J Cancer. 2003;  39 1904-1911
  • 30 Annovazzi A, Peeters M, Maenhout A. et al . 18-fluorodeoxyglucose positron emission tomography in nonendocrine neoplastic disorders of the gastrointestinal tract.  Gastroenterology. 2003;  125 1235-1245
  • 31 Anthuber M, Fuerst A, Elser F. et al . Outcome of laparoscopic surgery for rectal cancer in 101 patients.  Dis Colon Rectum. 2003;  46 1047-1053
  • 32 Arumugam P J, Joseph A, Sweerts M. et al . Severe dysplastic lesions in the colon - how aggressive should we be?.  Colorectal Dis. 2002;  4 345-347
  • 33 Atkin W, Cook C, Cuzick J. et al . Single flexible sigmoidoscopy screening to prevent colorectal cancer: baseline findings of a UK multicentre randomised trial.  Lancet. 2002;  359 1291-1300
  • 34 Atkin W S, Morson B C, Cuzick J. Long-term risk of colorectal cancer after excision of rectosigmoid adenomas.  N Engl J Med. 1992;  326 658-662
  • 35 Atkin W S, Saunders B P. Surveillance guidelines after removal of colorectal adenomatous polyps.  Gut. 2002;  51 (Suppl 5) V6-9
  • 36 Au H J, Mulder K E, Fields A L. Systematic review of management of colorectal cancer in elderly patients.  Clin Colorectal Cancer. 2003;  3 165-171
  • 37 Avidan B, Sonnenberg A, Schnell T G. et al . New occurrence and recurrence of neoplasms within 5 years of a screening colonoscopy.  Am J Gastroenterol. 2002;  97 1524-1529
  • 38 Aviv R I, Shyamalan G, Watkinson A. et al . Radiological palliation of malignant colonic obstruction.  Clin Radiol. 2002;  57 347-351
  • 39 Bansal P, Sonnenberg A. Risk factors of colorectal cancer in inflammatory bowel disease.  Am J Gastroenterol. 1996;  91 44-48
  • 40 Barillari P, Ramacciato G, De Angelis R. et al . Effect of preoperative colonoscopy on the incidence of synchronous and metachronous neoplasms.  Acta Chir Scand. 1990;  156 163-166
  • 41 Baron J A, Cole B F, Mott L. et al . Neoplastic and antineoplastic effects of beta-carotene on colorectal adenoma recurrence: results of a randomized trial.  J Natl Cancer Inst. 2003;  95 717-722
  • 42 Baron J A, Cole B F, Sandler R S. et al . A randomized trial of aspirin to prevent colorectal adenomas.  N Engl J Med. 2003;  348 891-899
  • 43 Baron J A, Sandler R S, Haile R W. et al . Folate intake, alcohol consumption, cigarette smoking, and risk of colorectal adenomas.  J Natl Cancer Inst. 1998;  90 57-62
  • 44 Baron T H, Dean P A, Yates M R 3rd. et al . Expandable metal stents for the treatment of colonic obstruction: techniques and outcomes.  Gastrointest Endosc. 1998;  47 277-286
  • 45 Barrier A, Houry S, Huguier M. The appropriate use of colonoscopy in the curative management of colorectal cancer.  Int J Colorectal Dis. 1998;  13 93-98
  • 46 Barrier A, Martel P, Gallot D. et al . Long-term functional results of colonic J pouch versus straight coloanal anastomosis.  Br J Surg. 1999;  86 1176-1179
  • 47 Barton J B, Langdale L A, Cummins J S. et al . The utility of routine preoperative computed tomography scanning in the management of veterans with colon cancer.  Am J Surg. 2002;  183 499-503
  • 48 Beets-Tan R G. MRI in rectal cancer: the T stage and circumferential resection margin.  Colorectal Dis. 2003;  5 392-395
  • 49 Befrits R, Ljung T, Jaramillo E. et al . Low-grade dysplasia in extensive, long-standing inflammatory bowel disease: a follow-up study.  Dis Colon Rectum. 2002;  45 615-620
  • 50 Benamouzig R, Deyra J, Martin A. et al . Daily soluble aspirin and prevention of colorectal adenoma recurrence: one-year results of the APACC trial.  Gastroenterology. 2003;  125 328-336
  • 51 Bensen S, Mott L A, Dain B. et al . The colonoscopic miss rate and true one-year recurrence of colorectal neoplastic polyps. Polyp Prevention Study Group.  Am J Gastroenterol. 1999;  94 194-199
  • 52 Benson A B 3rd, Desch C E, Flynn P J. et al . 2000 update of American Society of Clinical Oncology colorectal cancer surveillance guidelines.  J Clin Oncol. 2000;  18 3586-3588
  • 53 Berman J M, Cheung R J, Weinberg D S. Surveillance after colorectal cancer resection.  Lancet. 2000;  355 395-399
  • 54 Bernstein C N, Blanchard J F, Kliewer E. et al . Cancer risk in patients with inflammatory bowel disease: a population-based study.  Cancer. 2001;  91 854-862
  • 55 Bernstein C N, Shanahan F, Weinstein W M. Are we telling patients the truth about surveillance colonoscopy in ulcerative colitis?.  Lancet. 1994;  343 71-74
  • 56 Berry D P, Clarke P, Hardcastle J D. et al . Randomized trial of the addition of flexible sigmoidoscopy to faecal occult blood testing for colorectal neoplasia population screening.  Br J Surg. 1997;  84 1274-1276
  • 57 Bertario L, Presciuttini S, Sala P. et al . Causes of death and postsurgical survival in familial adenomatous polyposis: results from the Italian Registry. Italian Registry of Familial Polyposis Writing Committee.  Semin Surg Oncol. 1994;  10 225-234
  • 58 Bertario L, Russo A, Sala P. et al . Predictors of metachronous colorectal neoplasms in sporadic adenoma patients.  Int J Cancer. 2003;  105 82-87
  • 59 Bertario L, Russo A, Sala P. et al . Multiple approach to the exploration of genotype-phenotype correlations in familial adenomatous polyposis.  J Clin Oncol. 2003;  21 1698-1707
  • 60 Beynon J. An evaluation of the role of rectal endosonography in rectal cancer.  Ann R Coll Surg Engl. 1989;  71 131-139
  • 61 Binder V, Hendriksen C, Kreiner S. Prognosis in Crohn’s disease - based on results from a regional patient group from the county of Copenhagen.  Gut. 1985;  26 146-150
  • 62 Bingham S A, Day N E, Luben R. et al . Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study.  Lancet. 2003;  361 1496-1501
  • 63 Birkner B R. [Evidence-based prevention of colorectal carcinoma].  Dtsch Med Wochenschr. 2003;  128 2598-2603
  • 64 Boardman L A, Thibodeau S N, Schaid D J. et al . Increased risk for cancer in patients with the Peutz-Jeghers syndrome.  Ann Intern Med. 1998;  128 896-899
  • 65 Bohr J, Tysk C, Eriksson S. et al . Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients.  Gut. 1996;  39 846-851
  • 66 Bokey E L, Ojerskog B, Chapuis P H. et al . Local recurrence after curative excision of the rectum for cancer without adjuvant therapy: role of total anatomical dissection.  Br J Surg. 1999;  86 1164-1170
  • 67 Boks D E, Trujillo A P, Voogd A C. et al . Survival analysis of endometrial carcinoma associated with hereditary nonpolyposis colorectal cancer.  Int J Cancer. 2002;  102 198-200
  • 68 Bond J H. Clinical relevance of the small colorectal polyp.  Endoscopy. 2001;  33 454-457
  • 69 Bonelli L, Martines H, Conio M. et al . Family history of colorectal cancer as a risk factor for benign and malignant tumours of the large bowel. A case-control study.  Int J Cancer. 1988;  41 513-517
  • 70 Bostick R M, Potter J D, McKenzie D R. et al . Reduced risk of colon cancer with high intake of vitamin E: the Iowa Women’s Health Study.  Cancer Res. 1993;  53 4230-4237
  • 71 Botterill I D, Blunt D M, Quirke P. et al . Evaluation of the role of pre-operative magnetic resonance imaging in the management of rectal cancer.  Colorectal Dis. 2001;  3 295-303
  • 72 Bradshaw N, Holloway S, Penman I. et al . Colonoscopy surveillance of individuals at risk of familial colorectal cancer.  Gut. 2003;  52 1748-1751
  • 73 Brenner H, Arndt V, Sturmer T. et al . Long-lasting reduction of risk of colorectal cancer following screening endoscopy.  Br J Cancer. 2001;  85 972-976
  • 74 Brooker J C, Saunders B P, Shah S G. et al . Total colonic dye-spray increases the detection of diminutive adenomas during routine colonoscopy: a randomized controlled trial.  Gastrointest Endosc. 2002;  56 333-338
  • 75 Brown G, Radcliffe A G, Newcombe R G. et al . Preoperative assessment of prognostic factors in rectal cancer using high-resolution magnetic resonance imaging.  Br J Surg. 2003;  90 355-364
  • 76 Brown G, Richards C J, Newcombe R G. et al . Rectal carcinoma: thin-section MR imaging for staging in 28 patients.  Radiology. 1999;  211 215-222
  • 77 Bruch H P, Schwandner O. Die totale mesoraktale Exzision beim Rektumkarzinom - das Dissektionsprinzip ohne kontrollierte Daten.  Viszeralchirurgie. 2002;  37 6-11
  • 78 Bruinvels D J, Stiggelbout A M, Kievit J. et al . Follow-up of patients with colorectal cancer. A meta-analysis.  Ann Surg. 1994;  219 174-182
  • 79 Bulow S. Clinical features in familial polyposis coli. Results of the Danish Polyposis Register.  Dis Colon Rectum. 1986;  29 102-107
  • 80 Bulow S. Results of national registration of familial adenomatous polyposis.  Gut. 2003;  52 742-746
  • 81 Bulow S, Christensen I J, Harling H. et al . Recurrence and survival after mesorectal excision for rectal cancer.  Br J Surg. 2003;  90 974-980
  • 82 Burdick D, Prior J T. Peutz-Jeghers syndrome. A clinicopathologic study of a large family with a 27-year follow-up.  Cancer. 1982;  50 2139-2146
  • 83 Burke C A, Beck G J, Church J M. et al . The natural history of untreated duodenal and ampullary adenomas in patients with familial adenomatous polyposis followed in an endoscopic surveillance program.  Gastrointest Endosc. 1999;  49 358-364
  • 84 Burke W, Petersen G, Lynch P. et al . Recommendations for follow-up care of individuals with an inherited predisposition to cancer. I. Hereditary nonpolyposis colon cancer. Cancer Genetics Studies Consortium.  Jama. 1997;  277 915-919
  • 85 Burt R W. Screening of patients with a positive family history of colorectal cancer.  Gastrointest Endosc Clin N Am. 1997;  7 65-79
  • 86 Burton S, Eddy B, Li W Y. et al . Reliability of pre-operative biopsies in the histological grading of colorectal adenocarcinomas.  Ann R Coll Surg Engl. 2003;  85 23-25
  • 87 Busstra M C, Siezen C L, Grubben M J. et al . Tissue levels of fish fatty acids and risk of colorectal adenomas: a case-control study (Netherlands).  Cancer Causes Control. 2003;  14 269-276
  • 88 Cairns S, Scholefield J H. Guidelines for colorectal cancer screening in high risk groups.  Gut. 2002;  51 (Suppl 5) V1-2
  • 89 Cali R L, Pitsch R M, Thorson A G. et al . Cumulative incidence of metachronous colorectal cancer.  Dis Colon Rectum. 1993;  36 388-393
  • 90 Camma C, Giunta M, Fiorica F. et al . Preoperative radiotherapy for resectable rectal cancer: A meta-analysis.  Jama. 2000;  284 1008-1015
  • 91 Cao Y, Pieretti M, Marshall J. et al . Challenge in the differentiation between attenuated familial adenomatous polyposis and hereditary nonpolyposis colorectal cancer: case report with review of the literature.  Am J Gastroenterol. 2002;  97 1822-1827
  • 92 Caplin S, Cerottini J P, Bosman F T. et al . For patients with Dukes’ B (TNM Stage II) colorectal carcinoma, examination of six or fewer lymph nodes is related to poor prognosis.  Cancer. 1998;  83 666-672
  • 93 Ceelen W, Pattyn P. Total mesorectal excision in the treatment of rectal cancer: a review.  Acta Chir Belg. 2000;  100 94-99
  • 94 Chan A T, Giovannucci E L, Schernhammer E S. et al . A prospective study of aspirin use and the risk for colorectal adenoma.  Ann Intern Med. 2004;  140 157-166
  • 95 Chao A, Thun M J, Jacobs E J. et al . Cigarette smoking and colorectal cancer mortality in the cancer prevention study II.  J Natl Cancer Inst. 2000;  92 1888-1896
  • 96 Chapman M A, Buckley D, Henson D B. et al . Preoperative carcinoembryonic antigen is related to tumour stage and long-term survival in colorectal cancer.  Br J Cancer. 1998;  78 1346-1349
  • 97 Charnley R M, Morris D L, Dennison A R. et al . Detection of colorectal liver metastases using intraoperative ultrasonography.  Br J Surg. 1991;  78 45-48
  • 98 Chen C D, Yen M F, Wang W M. et al . A case-cohort study for the disease natural history of adenoma-carcinoma and de novo carcinoma and surveillance of colon and rectum after polypectomy: implication for efficacy of colonoscopy.  Br J Cancer. 2003;  88 1866-1873
  • 99 Chen H S, Sheen-Chen S M. Synchronous and „early” metachronous colorectal adenocarcinoma: analysis of prognosis and current trends.  Dis Colon Rectum. 2000;  43 1093-1099
  • 100 Choi H J, Choi Y Y, Hong S H. Incidence and prognostic implications of isolated tumor cells in lymph nodes from patients with Dukes B colorectal carcinoma.  Dis Colon Rectum. 2002;  45 750-755; discussion 755 - 756
  • 101 Choi P M, Nugent F W, Schoetz D J Jr. et al . Colonoscopic surveillance reduces mortality from colorectal cancer in ulcerative colitis.  Gastroenterology. 1993;  105 418-424
  • 102 Church J, Burke C, McGannon E. et al . Risk of rectal cancer in patients after colectomy and ileorectal anastomosis for familial adenomatous polyposis: a function of available surgical options.  Dis Colon Rectum. 2003;  46 1175-1181
  • 103 Church J M, Gibbs P, Chao M W. et al . Optimizing the outcome for patients with rectal cancer.  Dis Colon Rectum. 2003;  46 389-402
  • 104 Church J M, McGannon E, Burke C. et al . Teenagers with familial adenomatous polyposis: what is their risk for colorectal cancer?.  Dis Colon Rectum. 2002;  45 887-889
  • 105 Church J M, McGannon E, Hull-Boiner S. et al . Gastroduodenal polyps in patients with familial adenomatous polyposis.  Dis Colon Rectum. 1992;  35 1170-1173
  • 106 Citarda F, Tomaselli G, Capocaccia R. et al . Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidence.  Gut. 2001;  48 812-815
  • 107 Clark L C, Cantor K P, Allaway W H. Selenium in forage crops and cancer mortality in U.S. counties.  Arch Environ Health. 1991;  46 37-42
  • 108 Clark L C, Combs G F Jr, Turnbull B W. et al . Effects of selenium supplementation for cancer prevention in patients with carcinoma of the skin. A randomized controlled trial. Nutritional Prevention of Cancer Study Group.  Jama. 1996;  276 1957-1963
  • 109 Coburn M C, Pricolo V E, DeLuca F G. et al . Malignant potential in intestinal juvenile polyposis syndromes.  Ann Surg Oncol. 1995;  2 386-391
  • 110 Compton C, Fenoglio-Preiser C M, Pettigrew N. et al . American Joint Committee on Cancer Prognostic Factors Consensus Conference: Colorectal Working Group.  Cancer. 2000;  88 1739-1757
  • 111 Compton C C. Pathology report in colon cancer: what is prognostically important?.  Dig Dis. 1999;  17 67-79
  • 112 Compton C C. Updated protocol for the examination of specimens from patients with carcinomas of the colon and rectum, excluding carcinoid tumors, lymphomas, sarcomas, and tumors of the vermiform appendix: a basis for checklists. Cancer Committee.  Arch Pathol Lab Med. 2000;  124 1016-1025
  • 113 Connell W R, Lennard-Jones J E, Williams C B. et al . Factors affecting the outcome of endoscopic surveillance for cancer in ulcerative colitis.  Gastroenterology. 1994;  107 934-944
  • 114 Connell W R, Talbot I C, Harpaz N. et al . Clinicopathological characteristics of colorectal carcinoma complicating ulcerative colitis.  Gut. 1994;  35 1419-1423
  • 115 Crane C H, Janjan N A, Abbruzzese J L. et al . Effective pelvic symptom control using initial chemoradiation without colostomy in metastatic rectal cancer.  Int J Radiat Oncol Biol Phys. 2001;  49 107-116
  • 116 Cruz-Correa M, Hylind L M, Romans K E. et al . Long-term treatment with sulindac in familial adenomatous polyposis: a prospective cohort study.  Gastroenterology. 2002;  122 641-645
  • 117 Cunningham D, Pyrhonen S, James R D. et al . Randomised trial of irinotecan plus supportive care versus supportive care alone after fluorouracil failure for patients with metastatic colorectal cancer.  Lancet. 1998;  352 1413-1418
  • 118 De Cosse J J, Bulow S, Neale K. et al . Rectal cancer risk in patients treated for familial adenomatous polyposis. The Leeds Castle Polyposis Group.  Br J Surg. 1992;  79 1372-1375
  • 119 de Gramont A, Figer A, Seymour M. et al . Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer.  J Clin Oncol. 2000;  18 2938-2947
  • 120 de Vos tot Nederveen Cappel W H, Jarvinen H J, Bjork J. et al . Worldwide survey among polyposis registries of surgical management of severe duodenal adenomatosis in familial adenomatous polyposis.  Br J Surg. 2003;  90 705-710
  • 121 de Vos tot Nederveen Cappel W H, Nagengast F M, Griffioen G. et al . Surveillance for hereditary nonpolyposis colorectal cancer: a long-term study on 114 families.  Dis Colon Rectum. 2002;  45 1588-1594
  • 122 Debatin J F, Lauenstein T C. Virtual magnetic resonance colonography.  Gut. 2003;  52 (Suppl 4) iv17-22
  • 123 Dehni N, Parc R, Church J M. Colonic J-pouch-anal anastomosis for rectal cancer.  Dis Colon Rectum. 2003;  46 667-675
  • 124 Deinlein P, Reulbach U, Stolte M. et al . [Risk factors for lymphatic metastasis from pT1 colorectal adenocarcinoma].  Pathologe. 2003;  24 387-393
  • 125 Deneo-Pellegrini H, Boffetta P, De Stefani E. et al . Plant foods and differences between colon and rectal cancers.  Eur J Cancer Prev. 2002;  11 369-375
  • 126 Desai D C, Neale K F, Talbot I C. et al . Juvenile polyposis.  Br J Surg. 1995;  82 14-17
  • 127 Desch C E, Benson A B 3rd, Smith T J. et al . Recommended colorectal cancer surveillance guidelines by the American Society of Clinical Oncology.  J Clin Oncol. 1999;  17 1312
  • 128 Dixon M F, Brown L J, Gilmour H M. et al . Observer variation in the assessment of dysplasia in ulcerative colitis.  Histopathology. 1988;  13 385-397
  • 129 Dong S M, Traverso G, Johnson C. et al . Detecting colorectal cancer in stool with the use of multiple genetic targets.  J Natl Cancer Inst. 2001;  93 858-865
  • 130 Doran J, Hardcastle J D. Bleeding patterns in colorectal cancer: the effect of aspirin and the implications for faecal occult blood testing.  Br J Surg. 1982;  69 711-713
  • 131 Douillard J Y, Cunningham D, Roth A D. et al . Irinotecan combined with fluorouracil compared with fluorouracil alone as first-line treatment for metastatic colorectal cancer: a multicentre randomised trial.  Lancet. 2000;  355 1041-1047
  • 132 Dove-Edwin I, Boks D, Goff S. et al . The outcome of endometrial carcinoma surveillance by ultrasound scan in women at risk of hereditary nonpolyposis colorectal carcinoma and familial colorectal carcinoma.  Cancer. 2002;  94 1708-1712
  • 133 Dube S, Heyen F, Jenicek M. Adjuvant chemotherapy in colorectal carcinoma: results of a meta-analysis.  Dis Colon Rectum. 1997;  40 35-41
  • 134 Duff S E, O’Dwyer S T, Hulten L. et al . Dysplasia in the ileoanal pouch.  Colorectal Dis. 2002;  4 420-429
  • 135 Duffy M J. Carcinoembryonic antigen as a marker for colorectal cancer: is it clinically useful?.  Clin Chem. 2001;  47 624-630
  • 136 Duffy M J, van Dalen A, Haglund C. et al . Clinical utility of biochemical markers in colorectal cancer: European Group on Tumour Markers (EGTM) guidelines.  Eur J Cancer. 2003;  39 718-727
  • 137 Dworak O, Keilholz L, Hoffmann A. Pathological features of rectal cancer after preoperative radiochemotherapy.  Int J Colorectal Dis. 1997;  12 19-23
  • 138 Eaden J, Abrams K, Ekbom A. et al . Colorectal cancer prevention in ulcerative colitis: a case-control study.  Aliment Pharmacol Ther. 2000;  14 145-153
  • 139 Eaden J, Abrams K, McKay H. et al . Inter-observer variation between general and specialist gastrointestinal pathologists when grading dysplasia in ulcerative colitis.  J Pathol. 2001;  194 152-157
  • 140 Eaden J A, Abrams K R, Mayberry J F. The risk of colorectal cancer in ulcerative colitis: a meta-analysis.  Gut. 2001;  48 526-535
  • 141 Early D S, Hill K, Burk R. et al . Selenoprotein levels in patients with colorectal adenomas and cancer.  Am J Gastroenterol. 2002;  97 745-748
  • 142 Eckardt V F, Bernhard G. Nachsorge beim kolorektalen Karzinom. Eine Analyse von Effektivität und Kosten.  Deutsches Ärzteblatt. 1997;  94 A456-462
  • 143 Edwards D P, Leppington-Clarke A, Sexton R. et al . Stoma-related complications are more frequent after transverse colostomy than loop ileostomy: a prospective randomized clinical trial.  Br J Surg. 2001;  88 360-363
  • 144 Eisen G M, Kim C Y, Fleischer D E. et al . High-resolution chromoendoscopy for classifying colonic polyps: a multicenter study.  Gastrointest Endosc. 2002;  55 687-694
  • 145 Ekbom A, Helmick C, Zack M. et al . Increased risk of large-bowel cancer in Crohn’s disease with colonic involvement.  Lancet. 1990;  336 357-359
  • 146 Ekbom A, Helmick C, Zack M. et al . Ulcerative colitis and colorectal cancer. A population-based study.  N Engl J Med. 1990;  323 1228-1233
  • 147 Enblad P, Adami H O, Glimelius B. et al . The risk of subsequent primary malignant diseases after cancers of the colon and rectum. A nationwide cohort study.  Cancer. 1990;  65 2091-2100
  • 148 Engelsgjerd M, Farraye F A, Odze R D. Polypectomy may be adequate treatment for adenoma-like dysplastic lesions in chronic ulcerative colitis.  Gastroenterology. 1999;  117 1288-1294; discussion 1488 - 1491
  • 149 Enker W E. Total mesorectal excision - the new golden standard of surgery for rectal cancer.  Ann Med. 1997;  29 127-133
  • 150 Enker W E, Havenga K, Polyak T. et al . Abdominoperineal resection via total mesorectal excision and autonomic nerve preservation for low rectal cancer.  World J Surg. 1997;  21 715-720
  • 151 Enker W E, Merchant N, Cohen A M. et al . Safety and efficacy of low anterior resection for rectal cancer: 681 consecutive cases from a specialty service.  Ann Surg. 1999;  230 544-552
  • 152 Evans R C, Fear S, Ashby D. et al . Diet and colorectal cancer: an investigation of the lectin/galactose hypothesis.  Gastroenterology. 2002;  122 1784-1792
  • 153 Fairfield K M, Fletcher R H. Vitamins for chronic disease prevention in adults: scientific review.  Jama. 2002;  287 3116-3126
  • 154 Faivre J. [Endoscopic monitoring after excision of colorectal cancer].  J Chir (Paris). 1997;  134 283-285
  • 155 Farnell G F, Buckner J C, Cascino T L. et al . Brain metastases from colorectal carcinoma. The long term survivors.  Cancer. 1996;  78 711-716
  • 156 Farouk R, Ratnaval C D, Monson J R. et al . Staged delivery of Nd:YAG laser therapy for palliation of advanced rectal carcinoma.  Dis Colon Rectum. 1997;  40 156-160
  • 157 Fenton P A, Clarke S E, Owen W. et al . Cribriform variant papillary thyroid cancer: a characteristic of familial adenomatous polyposis.  Thyroid. 2001;  11 193-197
  • 158 Feuer D J, Broadley K E, Shepherd J H. et al . Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer.  Cochrane Database Syst Rev. 2000;  CD002764
  • 159 Ficari F, Cama A, Valanzano R. et al . APC gene mutations and colorectal adenomatosis in familial adenomatous polyposis.  Br J Cancer. 2000;  82 348-353
  • 160 Fielding L P, Arsenault P A, Chapuis P H. et al . Clinicopathological staging for colorectal cancer: an International Documentation System (IDS) and an International Comprehensive Anatomical Terminology (ICAT).  J Gastroenterol Hepatol. 1991;  6 325-344
  • 161 Fielding L P, Phillips R K, Hittinger R. Factors influencing mortality after curative resection for large bowel cancer in elderly patients.  Lancet. 1989;  1 595-597
  • 162 Figueras J, Valls C, Rafecas A. et al . Resection rate and effect of postoperative chemotherapy on survival after surgery for colorectal liver metastases.  Br J Surg. 2001;  88 980-985
  • 163 Figueredo A, Germond C, Maroun J. et al . Adjuvant therapy for stage II colon cancer after complete resection. Provincial Gastrointestinal Disease Site Group.  Cancer Prev Control. 1997;  1 379-392
  • 164 Fisher B, Wolmark N, Rockette H. et al . Postoperative adjuvant chemotherapy or radiation therapy for rectal cancer: results from NSABP protocol R-01.  J Natl Cancer Inst. 1988;  80 21-29
  • 165 Fisher D A, Jeffreys A, Grambow S C. et al . Mortality and follow-up colonoscopy after colorectal cancer.  Am J Gastroenterol. 2003;  98 901-906
  • 166 Focan C, Bury J, Beauduin M. et al . Adjuvant intraportal chemotherapy for Dukes B2 and C colorectal cancer also receiving systemic treatment: results of a multicenter randomized trial. Groupe Regional d’Etude du Cancer Colo-Rectal (Belgium).  Anticancer Drugs. 2000;  11 549-554
  • 167 Foley T R, McGarrity T J, Abt A B. Peutz-Jeghers syndrome: a clinicopathologic survey of the „Harrisburg family” with a 49-year follow-up.  Gastroenterology. 1988;  95 1535-1540
  • 168 Foulkes W D. A tale of four syndromes: familial adenomatous polyposis, Gardner syndrome, attenuated APC and Turcot syndrome.  Qjm. 1995;  88 853-863
  • 169 Franceschi S, La Vecchia C. Oral contraceptives and colorectal tumors. A review of epidemiologic studies.  Contraception. 1998;  58 335-343
  • 170 Francini G, Petrioli R, Lorenzini L. et al . Folinic acid and 5-fluorouracil as adjuvant chemotherapy in colon cancer.  Gastroenterology. 1994;  106 899-906
  • 171 Francois Y, Nemoz C J, Baulieux J. et al . Influence of the interval between preoperative radiation therapy and surgery on downstaging and on the rate of sphincter-sparing surgery for rectal cancer: the Lyon R90 - 01 randomized trial.  J Clin Oncol. 1999;  17 2396
  • 172 Frazier A L, Colditz G A, Fuchs C S. et al . Cost-effectiveness of screening for colorectal cancer in the general population.  Jama. 2000;  284 1954-1961
  • 173 Friedenreich C M, Orenstein M R. Physical activity and cancer prevention: etiologic evidence and biological mechanisms.  J Nutr. 2002;  132 3456S-3464S
  • 174 Frühmorgen P. et al . Kolorektale Polypen. Empfehlungen der Deutschen Gesellschaft für Verdauungs- und Stoffwechselkrankheiten (DGVS) für die Durchführung endoskopischer Untersuchungen. 3. Auflage.  Demeter. 2000;  127-134
  • 175 Frühmorgen P, Rufle W, Kobras S. et al . [Endoscopic Therapy of Early Colorectal Cancer (pT1) - A Prospective Study].  Z Gastroenterol. 2003;  41 703-710
  • 176 Frykholm G J, Glimelius B, Pahlman L. Preoperative or postoperative irradiation in adenocarcinoma of the rectum: final treatment results of a randomized trial and an evaluation of late secondary effects.  Dis Colon Rectum. 1993;  36 564-572
  • 177 Frykholm G J, Pahlman L, Glimelius B. Combined chemo- and radiotherapy vs. radiotherapy alone in the treatment of primary, nonresectable adenocarcinoma of the rectum.  Int J Radiat Oncol Biol Phys. 2001;  50 427-434
  • 178 Fuchs C S, Giovannucci E L, Colditz G A. et al . A prospective study of family history and the risk of colorectal cancer.  N Engl J Med. 1994;  331 1669-1674
  • 179 Fuchs C S, Giovannuci E L, Colditz G A. et al . Dietary fiber and the risk of colorectal cancer and adenoma in women.  N Engl J Med. 1999;  340 169-176
  • 180 Fuchs C S, Willett W C, Colditz G A. et al . The influence of folate and multivitamin use on the familial risk of colon cancer in women.  Cancer Epidemiol Biomarkers Prev. 2002;  11 227-234
  • 181 Fung T, Hu F B, Fuchs C. et al . Major dietary patterns and the risk of colorectal cancer in women.  Arch Intern Med. 2003;  163 309-314
  • 182 Furst A, Suttner S, Agha A. et al . Colonic J-pouch vs. coloplasty following resection of distal rectal cancer: early results of a prospective, randomized, pilot study.  Dis Colon Rectum. 2003;  46 1161-1166
  • 183 Galle T S, Juel K, Bulow S. Causes of death in familial adenomatous polyposis.  Scand J Gastroenterol. 1999;  34 808-812
  • 184 Gartner U, Braun G D, Held K. et al .Physical complaints, stress and quality of life of oncologic patients. Effects and patient assessment in inpatient rehabilitation. Munich; Med Klin 1996 91: 501-508
  • 185 Gastinger I, Marusch F. Evidence-based surgery in colon carcinoma.  Zentralbl Chir. 2001;  126 283-288
  • 186 Geul K W, Bosman F T, van Blankenstein M. et al . Prevention of colorectal cancer. Costs and effectiveness of sigmoidoscopy.  Scand J Gastroenterol Suppl. 1997;  223 79-87
  • 187 Gevers A M, Macken E, Hiele M. et al . Endoscopic laser therapy for palliation of patients with distal colorectal carcinoma: analysis of factors influencing long-term outcome.  Gastrointest Endosc. 2000;  51 580-585
  • 188 Ghadirian P, Lacroix A, Maisonneuve P. et al . Nutritional factors and colon carcinoma: a case-control study involving French Canadians in Montreal, Quebec, Canada.  Cancer. 1997;  80 858-864
  • 189 Giacchetti S, Itzhaki M, Gruia G. et al . Long-term survival of patients with unresectable colorectal cancer liver metastases following infusional chemotherapy with 5-fluorouracil, leucovorin, oxaliplatin and surgery.  Ann Oncol. 1999;  10 663-669
  • 190 Giacosa A, Franceschi S, La Vecchia C. et al . Energy intake, overweight, physical exercise and colorectal cancer risk.  Eur J Cancer Prev. 1999;  8 (Suppl 1) S53-60
  • 191 Giardiello F M, Brensinger J D, Tersmette A C. et al . Very high risk of cancer in familial Peutz-Jeghers syndrome.  Gastroenterology. 2000;  119 1447-1453
  • 192 Giardiello F M, Hamilton S R, Krush A J. et al . Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis.  N Engl J Med. 1993;  328 1313-1316
  • 193 Giardiello F M, Welsh S B, Hamilton S R. et al . Increased risk of cancer in the Peutz-Jeghers syndrome.  N Engl J Med. 1987;  316 1511-1514
  • 194 Giardiello F M, Yang V W, Hylind L M. et al . Primary chemoprevention of familial adenomatous polyposis with sulindac.  N Engl J Med. 2002;  346 1054-1059
  • 195 Gilbert J M, Vaizey C J, Cassell P G. et al . Feasibility study of colonoscopy as the primary screening investigation in relatives of patients with colorectal cancer.  Ann R Coll Surg Engl. 2001;  83 415-419
  • 196 Gillen C D, Andrews H A, Prior P. et al . Crohn’s disease and colorectal cancer.  Gut. 1994;  35 651-655
  • 197 Giovannucci E. An updated review of the epidemiological evidence that cigarette smoking increases risk of colorectal cancer.  Cancer Epidemiol Biomarkers Prev. 2001;  10 725-731
  • 198 Giovannucci E. Modifiable risk factors for colon cancer.  Gastroenterol Clin North Am. 2002;  31 925-943
  • 199 Giovannucci E. Diet, body weight, and colorectal cancer: a summary of the epidemiologic evidence.  J Womens Health (Larchmt). 2003;  12 173-182
  • 200 Giovannucci E, Stampfer M J, Colditz G A. et al . Multivitamin use, folate and colon cancer in women in the nurses’ health study.  Ann Intern Med. 1998;  129 517-524
  • 201 Gnauck R, Macrae F A, Fleisher M. How to perform the fecal occult blood test.  CA Cancer J Clin. 1984;  34 134-147
  • 202 Goldberg R M, Fleming T R, Tangen C M. et al . Surgery for recurrent colon cancer: strategies for identifying resectable recurrence and success rates after resection. Eastern Cooperative Oncology Group, the North Central Cancer Treatment Group, and the Southwest Oncology Group.  Ann Intern Med. 1998;  129 27-35
  • 203 Goldstein N S, Sanford W, Coffey M. et al . Lymph node recovery from colorectal resection specimens removed for adenocarcinoma. Trends over time and a recommendation for a minimum number of lymph nodes to be recovered.  Am J Clin Pathol. 1996;  106 209-216
  • 204 Goldstein N S, Soman A, Sacksner J. Disparate surgical margin lengths of colorectal resection specimens between in vivo and in vitro measurements. The effects of surgical resection and formalin fixation on organ shrinkage.  Am J Clin Pathol. 1999;  111 349-351
  • 205 Goligher J. Studies of lymphatic dissemination of colorectal carcinoma. In: Surgery of the Anus, Rectum and Colon. 5th edition London; Bailliere Tindall 1984: 774
  • 206 Gondal G, Grotmol T, Hofstad B. et al . The Norwegian Colorectal Cancer Prevention (NORCCAP) screening study: baseline findings and implementations for clinical work-up in age groups 50 - 64 years.  Scand J Gastroenterol. 2003;  38 635-642
  • 207 Graham R A, Wang S, Catalano P J. et al . Postsurgical surveillance of colon cancer: preliminary cost analysis of physician examination, carcinoembryonic antigen testing, chest x-ray, and colonoscopy.  Ann Surg. 1998;  228 59-63
  • 208 Greegor D H. Occult blood testing for detection of asymptomatic colon cancer.  Cancer. 1971;  28 131-134
  • 209 Green R J, Metlay J P, Propert K. et al . Surveillance for second primary colorectal cancer after adjuvant chemotherapy: an analysis of Intergroup 0089.  Ann Intern Med. 2002;  136 261-269
  • 210 Greenberg P D, Bertario L, Gnauck R. et al . A prospective multicenter evaluation of new fecal occult blood tests in patients undergoing colonoscopy.  Am J Gastroenterol. 2000;  95 1331-1338
  • 211 Greenstein A J, Sachar D B, Smith H. et al . A comparison of cancer risk in Crohn’s disease and ulcerative colitis.  Cancer. 1981;  48 2742-2745
  • 212 Groves C J, Saunders B P, Spigelman A D. et al . Duodenal cancer in patients with familial adenomatous polyposis (FAP): results of a 10 year prospective study.  Gut. 2002;  50 636-641
  • 213 Gschwantler M, Kriwanek S, Langner E. et al . High-grade dysplasia and invasive carcinoma in colorectal adenomas: a multivariate analysis of the impact of adenoma and patient characteristics.  Eur J Gastroenterol Hepatol. 2002;  14 183-188
  • 214 Guillem J G, Bastar A L, Ng J. et al . Clustering of colorectal cancer in families of probands under 40 years of age.  Dis Colon Rectum. 1996;  39 1004-1007
  • 215 Guillem J G, Forde K A, Treat M R. et al . Colonoscopic screening for neoplasms in asymptomatic first-degree relatives of colon cancer patients. A controlled, prospective study.  Dis Colon Rectum. 1992;  35 523-529
  • 216 Gunderson L L, Sargent D J, Tepper J E. et al . Impact of T and N substage on survival and disease relapse in adjuvant rectal cancer: a pooled analysis.  Int J Radiat Oncol Biol Phys. 2002;  54 386-396
  • 217 Gyde S N, Prior P, Allan R N. et al . Colorectal cancer in ulcerative colitis: a cohort study of primary referrals from three centres.  Gut. 1988;  29 206-217
  • 218 Hall N R, Bishop D T, Stephenson B M. et al . Hereditary susceptibility to colorectal cancer. Relatives of early onset cases are particularly at risk.  Dis Colon Rectum. 1996;  39 739-743
  • 219 Hallbook O, Sjodahl R. Comparison between the colonic J pouch-anal anastomosis and healthy rectum: clinical and physiological function.  Br J Surg. 1997;  84 1437-1441
  • 220 Hamilton S R, Aaltonen L A. Pathology and Genetics of Tumours of the Digestive System. Lyon; IARC Press 2000
  • 221 Harach H R. Familial adenomatous polyposis associated with sporadic MEN 1 and thyroid carcinoma related to APC mutation.  Am J Surg Pathol. 2003;  27 412-413
  • 222 Hardcastle J D, Chamberlain J O, Robinson M H. et al . Randomised controlled trial of faecal-occult-blood screening for colorectal cancer.  Lancet. 1996;  348 1472-1477
  • 223 Hardt P D, Toepler M, Ngoumou B. et al . Measurement of fecal pyruvate kinase type M2 (tumor M2-PK) concentrations in patients with gastric cancer, colorectal cancer, colorectal adenomas and controls.  Anticancer Res. 2003;  23 851-853
  • 224 Harewood G C, Wiersema M J, Nelson H. et al . A prospective, blinded assessment of the impact of preoperative staging on the management of rectal cancer.  Gastroenterology. 2002;  123 24-32
  • 225 Harris G J, Church J M, Senagore A J. et al . Factors affecting local recurrence of colonic adenocarcinoma.  Dis Colon Rectum. 2002;  45 1029-1034
  • 226 Hartley J E, Lopez R A, Paty P B. et al . Resection of locally recurrent colorectal cancer in the presence of distant metastases: can it be justified?.  Ann Surg Oncol. 2003;  10 227-233
  • 227 Havenga K, Enker W E, McDermott K. et al . Male and female sexual and urinary function after total mesorectal excision with autonomic nerve preservation for carcinoma of the rectum.  J Am Coll Surg. 1996;  182 495-502
  • 228 Hawes R H. Does virtual colonoscopy have a major role in population-based screening?.  Gastrointest Endosc Clin N Am. 2002;  12 85-91
  • 229 Heald R J, Husband E M, Ryall R D. The mesorectum in rectal cancer surgery - the clue to pelvic recurrence?.  Br J Surg. 1982;  69 613-616
  • 230 Heald R J, Karanjia N D. Results of radical surgery for rectal cancer.  World J Surg. 1992;  16 848-857
  • 231 Heiskanen I, Kellokumpu I, Jarvinen H. Management of duodenal adenomas in 98 patients with familial adenomatous polyposis.  Endoscopy. 1999;  31 412-416
  • 232 Heiskanen I, Luostarinen T, Jarvinen H J. Impact of screening examinations on survival in familial adenomatous polyposis.  Scand J Gastroenterol. 2000;  35 1284-1287
  • 233 Hemminki K, Li X, Dong C. Second primary cancers after sporadic and familial colorectal cancer.  Cancer Epidemiol Biomarkers Prev. 2001;  10 793-798
  • 234 Herline A J, Meisinger L L, Rusin L C. et al . Is routine pouch surveillance for dysplasia indicated for ileoanal pouches?.  Dis Colon Rectum. 2003;  46 156-159
  • 235 Hermanek P. Polypectomy in the colorectum: histological and oncological aspects.  Endoscopy. 1983;  15 158-161
  • 236 Hermanek P. [Lymph nodes and malignant tumors].  Zentralbl Chir. 2000;  125 790-795
  • 237 Hermanek P. Methodik der histopathologischen Untersuchung von Resektionen kolorektaler Karzinome.  Chir Gastroenterol. 2000;  16 255-259
  • 238 Hermanek P. Lokale Therapie des Rektumkarzinoms. Verfahren in kurativer Intention. Berlin/Heidelberg/New York/Tokyo; Springer 1994
  • 239 Hermanek P, Guggenmoos-Holzmann I, Gall F P. Prognostic factors in rectal carcinoma. A contribution to the further development of tumor classification.  Dis Colon Rectum. 1989;  32 593-599
  • 240 Hermanek P, Hohenberger W. The importance of volume in colorectal cancer surgery.  Eur J Surg Oncol. 1996;  22 213-215
  • 241 Hermanek P Jr, Wiebelt H, Riedl S. et al . Long-term results of surgical therapy of colon cancer. Results of the Colorectal Cancer Study Group.  Chirurg. 1994;  65 287-297
  • 242 Hermanek P J. Multiviszerale Resektion beim kolorektalen Karzinom. Erfahrungen der SGKRK-Studie.  Langenbecks Arch Surg. 1992;  Kongressband 95-100
  • 243 Hernegger G S, Moore H G, Guillem J G. Attenuated familial adenomatous polyposis: an evolving and poorly understood entity.  Dis Colon Rectum. 2002;  45 127-134; discussion 134 - 136
  • 244 Hida J, Yasutomi M, Fujimoto K. et al . Functional outcome after low anterior resection with low anastomosis for rectal cancer using the colonic J-pouch. Prospective randomized study for determination of optimum pouch size.  Dis Colon Rectum. 1996;  39 986-991
  • 245 Hida J, Yasutomi M, Maruyama T. et al . Lymph node metastases detected in the mesorectum distal to carcinoma of the rectum by the clearing method: justification of total mesorectal excision.  J Am Coll Surg. 1997;  184 584-588
  • 246 Higaki S, Hashimoto S, Harada K. et al . Long-term follow-up of large flat colorectal tumors resected endoscopically.  Endoscopy. 2003;  35 845-849
  • 247 Hizawa K, Iida M, Matsumoto T. et al . Neoplastic transformation arising in Peutz-Jeghers polyposis.  Dis Colon Rectum. 1993;  36 953-957
  • 248 Ho Y H, Brown S, Heah S M. et al . Comparison of J-pouch and coloplasty pouch for low rectal cancers: a randomized, controlled trial investigating functional results and comparative anastomotic leak rates.  Ann Surg. 2002;  236 49-55
  • 249 Hoff P M, Ansari R, Batist G. et al . Comparison of oral capecitabine versus intravenous fluorouracil plus leucovorin as first-line treatment in 605 patients with metastatic colorectal cancer: results of a randomized phase III study.  J Clin Oncol. 2001;  19 2282-2292
  • 250 Hofgartner W T, Thorp M, Ramus M W. et al . Gastric adenocarcinoma associated with fundic gland polyps in a patient with attenuated familial adenomatous polyposis.  Am J Gastroenterol. 1999;  94 2275-2281
  • 251 Hsieh Y H, Lin H J, Tseng G Y. et al . Is submucosal epinephrine injection necessary before polypectomy? A prospective, comparative study.  Hepatogastroenterology. 2001;  48 1379-1382
  • 252 Huebner R H, Park K C, Shepherd J E. et al . A meta-analysis of the literature for whole-body FDG PET detection of recurrent colorectal cancer.  J Nucl Med. 2000;  41 1177-1189
  • 253 Hughes L J, Michels V V. Risk of hepatoblastoma in familial adenomatous polyposis.  Am J Med Genet. 1992;  43 1023-1025
  • 254 Hunerbein M. Endorectal ultrasound in rectal cancer.  Colorectal Dis. 2003;  5 402-405
  • 255 Hunerbein M, Totkas S, Moesta K T. et al . The role of transrectal ultrasound-guided biopsy in the postoperative follow-up of patients with rectal cancer.  Surgery. 2001;  129 164-169
  • 256 Hunt L M, Rooney P S, Hardcastle J D. et al . Endoscopic screening of relatives of patients with colorectal cancer.  Gut. 1998;  42 71-75
  • 257 Hurlstone D P, Cross S S, Adam I. et al . Efficacy of high magnification chromoscopic colonoscopy for the diagnosis of neoplasia in flat and depressed lesions of the colorectum: a prospective analysis.  Gut. 2004;  53 284-290
  • 258 Imperiale T F, Wagner D R, Lin C Y. et al . Risk of advanced proximal neoplasms in asymptomatic adults according to the distal colorectal findings.  N Engl J Med. 2000;  343 169-174
  • 259 Imperiale T F, Wagner D R, Lin C Y. et al . Results of screening colonoscopy among persons 40 to 49 years of age.  N Engl J Med. 2002;  346 1781-1785
  • 260 Inadomi J M. Update on the cost-effectiveness of screening for colorectal neoplasia.  Curr Opin Gastroenterol. 2003;  29 44-50
  • 261 Inoue T, Mori M, Shimono R. et al . Vascular invasion of colorectal carcinoma readily visible with certain stains.  Dis Colon Rectum. 1992;  35 34-39
  • 262 Iwashyna T J, Lamont E B. Effectiveness of adjuvant fluorouracil in clinical practice: a population-based cohort study of elderly patients with stage III colon cancer.  J Clin Oncol. 2002;  20 3992-3998
  • 263 Jaeger E E, Woodford-Richens K L, Lockett M. et al . An ancestral Ashkenazi haplotype at the HMPS/CRAC1 locus on 15q13-q14 is associated with hereditary mixed polyposis syndrome.  Am J Hum Genet. 2003;  72 1261-1267
  • 264 Jaffe R M, Kasten B, Young D S. et al . False-negative stool occult blood tests caused by ingestion of ascorbic acid (vitamin C).  Ann Intern Med. 1975;  83 824-826
  • 265 Jakobs R, Miola J, Eickhoff A. et al . Endoscopic laser palliation for rectal cancer - therapeutic outcome and complications in eighty-three consecutive patients.  Z Gastroenterol. 2002;  40 551-556
  • 266 Jarvinen H J, Aarnio M, Mustonen H. et al . Controlled 15-year trial on screening for colorectal cancer in families with hereditary nonpolyposis colorectal cancer.  Gastroenterology. 2000;  118 829-834
  • 267 Jass J R, Williams C B, Bussey H J. et al . Juvenile polyposis - a precancerous condition.  Histopathology. 1988;  13 619-630
  • 268 Jeevaratnam P, Cottier D S, Browett P J. et al . Familial giant hyperplastic polyposis predisposing to colorectal cancer: a new hereditary bowel cancer syndrome.  J Pathol. 1996;  179 20-25
  • 269 Jeffery G M, Hickey B E, Hider P. Follow-up strategies for patients treated for non-metastatic colorectal cancer.  Cochrane Database Syst Rev. 2002;  CD002200
  • 270 Johns L E, Houlston R S. A systematic review and meta-analysis of familial colorectal cancer risk.  Am J Gastroenterol. 2001;  96 2992-3003
  • 271 Johnson C D, Harmsen W S, Wilson L A. et al . Prospective blinded evaluation of computed tomographic colonography for screen detection of colorectal polyps.  Gastroenterology. 2003;  125 311-319
  • 272 Jorgensen O D, Kronborg O, Fenger C. A randomised study of screening for colorectal cancer using faecal occult blood testing: results after 13 years and seven biennial screening rounds.  Gut. 2002;  50 29-32
  • 273 Junginger T PH, Klimpfinger M. Klassifikation maligner Tumoren des Gastrointestinaltraktes I. Berlin/Heidelberg/New York; Springer 2002
  • 274 Kadmon M, Tandara A, Herfarth C. Duodenal adenomatosis in familial adenomatous polyposis coli. A review of the literature and results from the Heidelberg Polyposis Register.  Int J Colorectal Dis. 2001;  16 63-75
  • 275 Kalady M F, Clary B M, Tyler D S. et al . Pancreas-preserving duodenectomy in the management of duodenal familial adenomatous polyposis.  J Gastrointest Surg. 2002;  6 82-87
  • 276 Kapiteijn E, Marijnen C A, Nagtegaal I D. et al . Preoperative radiotherapy combined with total mesorectal excision for resectable rectal cancer.  N Engl J Med. 2001;  345 638-646
  • 277 Karanjia N D, Corder A P, Holdsworth P J. et al . Risk of peritonitis and fatal septicaemia and the need to defunction the low anastomosis.  Br J Surg. 1991;  78 196-198
  • 278 Karanjia N D, Heald R J. Stapled anastomoses and colon cancer recurrence.  Lancet. 1992;  340 849
  • 279 Karanjia N D, Schache D J, Heald R J. Function of the distal rectum after low anterior resection for carcinoma.  Br J Surg. 1992;  79 114-116
  • 280 Karita M, Cantero D, Okita K. Endoscopic diagnosis and resection treatment for flat adenoma with severe dysplasia.  Am J Gastroenterol. 1993;  88 1421-1423
  • 281 Karlen P, Kornfeld D, Brostrom O. et al . Is colonoscopic surveillance reducing colorectal cancer mortality in ulcerative colitis? A population based case control study.  Gut. 1998;  42 711-714
  • 282 Karnes W E. Epidemiology and etiology of sporadic colorectal adenocarcinoma.  Current opinion in Gastroenterology. 1994;  10 19-26
  • 283 Kemeny M M, Adak S, Gray B. et al . Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy - an intergroup study.  J Clin Oncol. 2002;  20 1499-1505
  • 284 Kerr D J, McArdle C S, Ledermann J. et al . Intrahepatic arterial versus intravenous fluorouracil and folinic acid for colorectal cancer liver metastases: a multicentre randomised trial.  Lancet. 2003;  361 368-373
  • 285 Khandker R K, Dulski J D, Kilpatrick J B. et al . A decision model and cost-effectiveness analysis of colorectal cancer screening and surveillance guidelines for average-risk adults.  Int J Technol Assess Health Care. 2000;  16 799-810
  • 286 Khot U P, Lang A W, Murali K. et al . Systematic review of the efficacy and safety of colorectal stents.  Br J Surg. 2002;  89 1096-1102
  • 287 Kiesslich R, Fritsch J, Holtmann M. et al . Methylene blue-aided chromoendoscopy for the detection of intraepithelial neoplasia and colon cancer in ulcerative colitis.  Gastroenterology. 2003;  124 880-888
  • 288 Kiesslich R, von Bergh M, Hahn M. et al . Chromoendoscopy with indigocarmine improves the detection of adenomatous and nonadenomatous lesions in the colon.  Endoscopy. 2001;  33 1001-1006
  • 289 Kievit J. Colorectal cancer follow-up: a reassessment of empirical evidence on effectiveness.  Eur J Surg Oncol. 2000;  26 322-328
  • 290 Kievit J. Follow-up of patients with colorectal cancer: numbers needed to test and treat.  Eur J Cancer. 2002;  38 986-999
  • 291 Kikuchi R, Takano M, Takagi K. et al . Management of early invasive colorectal cancer. Risk of recurrence and clinical guidelines.  Dis Colon Rectum. 1995;  38 1286-1295
  • 292 King J E, Dozois R R, Lindor N M. et al . Care of patients and their families with familial adenomatous polyposis.  Mayo Clin Proc. 2000;  75 57-67
  • 293 Kirchgatterer A, Hubner D, Aschl G. et al . [Colonoscopy and sigmoidoscopy in patients aged eighty years or older].  Z Gastroenterol. 2002;  40 951-956
  • 294 Kjeldsen B J, Kronborg O, Fenger C. et al . A prospective randomized study of follow-up after radical surgery for colorectal cancer.  Br J Surg. 1997;  84 666-669
  • 295 Knudsen A L, Bisgaard M L, Bulow S. Attenuated familial adenomatous polyposis (AFAP). A review of the literature.  Fam Cancer. 2003;  2 43-55
  • 296 Ko C W, Dominitz J A, Nguyen T D. Fecal occult blood testing in a general medical clinic: comparison between guaiac-based and immunochemical-based tests.  Am J Med. 2003;  115 111-114
  • 297 Kohne C H, Cunningham D, Di C F. et al . Clinical determinants of survival in patients with 5-fluorouracil-based treatment for metastatic colorectal cancer: results of a multivariate analysis of 3825 patients.  Ann Oncol. 2002;  13 308-317
  • 298 Koide N, Saito Y, Fujii T. et al . A case of hyperplastic polyposis of the colon with adenocarcinomas in hyperplastic polyps after long-term follow-up.  Endoscopy. 2002;  34 499-502
  • 299 Konings E J, Goldbohm R A, Brants H A. et al . Intake of dietary folate vitamers and risk of colorectal carcinoma: results from The Netherlands Cohort Study.  Cancer. 2002;  95 1421-1433
  • 300 Krasna M J, Flancbaum L, Cody R P. et al . Vascular and neural invasion in colorectal carcinoma. Incidence and prognostic significance.  Cancer. 1988;  61 1018-1023
  • 301 Kremer C, Barik S, Duffy S. Flexible outpatient hysteroscopy without anaesthesia: a safe, successful and well tolerated procedure.  Br J Obstet Gynaecol. 1998;  105 672-676
  • 302 Kronborg O, Fenger C, Olsen J. et al . Randomised study of screening for colorectal cancer with faecal-occult-blood test.  Lancet. 1996;  348 1467-1471
  • 303 Krook J E, Moertel C G, Gunderson L L. et al . Effective surgical adjuvant therapy for high-risk rectal carcinoma.  N Engl J Med. 1991;  324 709-715
  • 304 Kruse R, Rutten A, Lamberti C. et al . Muir-Torre phenotype has a frequency of DNA mismatch-repair-gene mutations similar to that in hereditary nonpolyposis colorectal cancer families defined by the Amsterdam criteria.  Am J Hum Genet. 1998;  63 63-70
  • 305 Kudo S, Kashida H, Nakajima T. et al . Endoscopic diagnosis and treatment of early colorectal cancer.  World J Surg. 1997;  21 694-701
  • 306 Kudo S, Kashida H, Tamura T. et al . Colonoscopic diagnosis and management of nonpolypoid early colorectal cancer.  World J Surg. 2000;  24 1081-1090
  • 307 Kudo S, Rubio C A, Teixeira C R. et al . Pit pattern in colorectal neoplasia: endoscopic magnifying view.  Endoscopy. 2001;  33 367-373
  • 308 Kune G A, Kune S, Watson L F. The role of heredity in the etiology of large bowel cancer: data from the Melbourne Colorectal Cancer Study.  World J Surg. 1989;  13 124-129
  • 309 Kwok H, Bissett I P, Hill G L. Preoperative staging of rectal cancer.  Int J Colorectal Dis. 2000;  15 9-20
  • 310 Kwok S P, Lau W Y, Leung K L. et al . Prospective analysis of the distal margin of clearance in anterior resection for rectal carcinoma.  Br J Surg. 1996;  83 969-972
  • 311 La Vecchia C, Negri E, Pelucchi C. et al . Dietary folate and colorectal cancer.  Int J Cancer. 2002;  102 545-547
  • 312 Labayle D, Boyer J, Drouhin F. et al . Sulindac in familial adenomatous polyposis.  Lancet. 1994;  343 417-418
  • 313 Lacy A M, Garcia-Valdecasas J C, Delgado S. et al . Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial.  Lancet. 2002;  359 2224-2229
  • 314 Langholz E, Munkholm P, Davidsen M. et al . Colorectal cancer risk and mortality in patients with ulcerative colitis.  Gastroenterology. 1992;  103 1444-1451
  • 315 Lashner B A, Provencher K S, Seidner D L. et al . The effect of folic acid supplementation on the risk for cancer or dysplasia in ulcerative colitis.  Gastroenterology. 1997;  112 29-32
  • 316 Lauenstein T C, Debatin J F. Magnetic resonance colonography with fecal tagging: an innovative approach without bowel cleansing.  Top Magn Reson Imaging. 2002;  13 435-444
  • 317 Law W L, Chu K W, Choi H K. Randomized clinical trial comparing loop ileostomy and loop transverse colostomy for faecal diversion following total mesorectal excision.  Br J Surg. 2002;  89 704-708
  • 318 Lazorthes F, Voigt J J, Roques J. et al . Distal intramural spread of carcinoma of the rectum correlated with lymph nodal involvement.  Surg Gynecol Obstet. 1990;  170 45-48
  • 319 Le Voyer T E, Sigurdson E R, Hanlon A L. et al . Colon cancer survival is associated with increasing number of lymph nodes analyzed: a secondary survey of intergroup trial INT-0089.  J Clin Oncol. 2003;  21 2912-2919
  • 320 Lee I M. Physical activity and cancer prevention - data from epidemiologic studies.  Med Sci Sports Exerc. 2003;  35 1823-1827
  • 321 Lee J H, Ahn J H, Bahng H. et al . Randomized trial of postoperative adjuvant therapy in stage II and III rectal cancer to define the optimal sequence of chemotherapy and radiotherapy: a preliminary report.  J Clin Oncol. 2002;  20 1751-1758
  • 322 Leggett B A, Devereaux B, Biden K. et al . Hyperplastic polyposis: association with colorectal cancer.  Am J Surg Pathol. 2001;  25 177-184
  • 323 Leggett B A, Young J P, Biden K. et al . Severe upper gastrointestinal polyposis associated with sparse colonic polyposis in a familial adenomatous polyposis family with an APC mutation at codon 1520.  Gut. 1997;  41 518-521
  • 324 Lehnert T, Golling M. [Posterior pelvic exenteration in locoregional recurrence of rectal carcinoma - indications, technique and outcome].  Chirurg. 2001;  72 1393-1401
  • 325 Lehnert T, Knaebel H P, Duck M. et al . Sequential hepatic and pulmonary resections for metastatic colorectal cancer.  Br J Surg. 1999;  86 241-243
  • 326 Leibl S, Tsybrovskyy O, Denk H. How many lymph nodes are necessary to stage early and advanced adenocarcinoma of the sigmoid colon and upper rectum?.  Virchows Arch. 2003;  443 133-138
  • 327 Leong A F. Selective total mesorectal excision for rectal cancer.  Dis Colon Rectum. 2000;  43 1237-1240
  • 328 Levin B, Hess K, Johnson C. Screening for colorectal cancer. A comparison of 3 fecal occult blood tests.  Arch Intern Med. 1997;  157 970-976
  • 329 Levy R. Sulindac in familial adenomatous polyposis.  N Engl J Med. 2002;  347 615
  • 330 Liberman H, Adams D R, Blatchford G J. et al . Clinical use of the self-expanding metallic stent in the management of colorectal cancer.  Am J Surg. 2000;  180 407-411; discussion 412
  • 331 Lichtenstein P, Holm N V, Verkasalo P K. et al . Environmental and heritable factors in the causation of cancer - analyses of cohorts of twins from Sweden, Denmark, and Finland.  N Engl J Med. 2000;  343 78-85
  • 332 Lieberman D A, Weiss D G. One-time screening for colorectal cancer with combined fecal occult-blood testing and examination of the distal colon.  N Engl J Med. 2001;  345 555-560
  • 333 Lieberman D A, Weiss D G, Bond J H. et al . Use of colonoscopy to screen asymptomatic adults for colorectal cancer. Veterans Affairs Cooperative Study Group 380.  N Engl J Med. 2000;  343 162-168
  • 334 Liersch T, Langer C, Jakob C. et al . Preoperative diagnostic procedures in locally advanced rectal carcinoma (> or = T3 or N +). What does endoluminal ultrasound achieve at staging and restaging (after neoadjuvant radiochemotherapy) in contrast to computed tomography?.  Chirurg. 2003;  74 224-234
  • 335 Liljegren A, Lindblom A, Rotstein S. et al . Prevalence and incidence of hyperplastic polyps and adenomas in familial colorectal cancer: correlation between the two types of colon polyps.  Gut. 2003;  52 1140-1147
  • 336 Limburg P J, Devens M E, Harrington J J. et al . Prospective evaluation of fecal calprotectin as a screening biomarker for colorectal neoplasia.  Am J Gastroenterol. 2003;  98 2299-2305
  • 337 Lin J K, Wang H S, Yang S H. et al . Comparison between straight and J-pouch coloanal anastomoses in surgery for rectal cancer.  Surg Today. 2002;  32 487-492
  • 338 Loftus E V Jr, Sandborn W J, Tremaine W J. et al . Risk of colorectal neoplasia in patients with primary sclerosing cholangitis.  Gastroenterology. 1996;  110 432-440
  • 339 Longo W E, Virgo K S, Johnson F E. et al . Risk factors for morbidity and mortality after colectomy for colon cancer.  Dis Colon Rectum. 2000;  43 83-91
  • 340 Lorenz M, Muller H H, Schramm H. et al . Randomized trial of surgery versus surgery followed by adjuvant hepatic arterial infusion with 5-fluorouracil and folinic acid for liver metastases of colorectal cancer. German Cooperative on Liver Metastases (Arbeitsgruppe Lebermetastasen).  Ann Surg. 1998;  228 756-762
  • 341 Lubin F, Rozen P, Arieli B. et al . Nutritional and lifestyle habits and water-fiber interaction in colorectal adenoma etiology.  Cancer Epidemiol Biomarkers Prev. 1997;  6 79-85
  • 342 Lynch H T, Casey M J, Shaw T G. et al . Hereditary Factors in Gynecologic Cancer.  Oncologist. 1998;  3 319-338
  • 343 Lynch H T, de la Chapelle A. Hereditary colorectal cancer.  N Engl J Med. 2003;  348 919-932
  • 344 Lynch H T, Smyrk T, McGinn T. et al . Attenuated familial adenomatous polyposis (AFAP). A phenotypically and genotypically distinctive variant of FAP.  Cancer. 1995;  76 2427-2433
  • 345 Lynch H T, Smyrk T C. Classification of familial adenomatous polyposis: a diagnostic nightmare.  Am J Hum Genet. 1998;  62 1288-1289
  • 346 Lynch H T, Thorson A G, McComb R D. et al . Familial adenomatous polyposis and extracolonic cancer.  Dig Dis Sci. 2001;  46 2325-2332
  • 347 Macdonald J S. Carcinoembryonic antigen screening: pros and cons.  Semin Oncol. 1999;  26 556-560
  • 348 Machado M, Nygren J, Goldman S. et al . Similar outcome after colonic pouch and side-to-end anastomosis in low anterior resection for rectal cancer: a prospective randomized trial.  Ann Surg. 2003;  238 214-220
  • 349 Mackay S G, Pager C K, Joseph D. et al . Assessment of the accuracy of transrectal ultrasonography in anorectal neoplasia.  Br J Surg. 2003;  90 346-350
  • 350 Macrae F A, St John D J. Relationship between patterns of bleeding and Hemoccult sensitivity in patients with colorectal cancers or adenomas.  Gastroenterology. 1982;  82 891-898
  • 351 Macrae F A, St John D J, Caligiore P. et al . Optimal dietary conditions for hemoccult testing.  Gastroenterology. 1982;  82 899-903
  • 352 Makela J T, Laitinen S O, Kairaluoma M I. Five-year follow-up after radical surgery for colorectal cancer. Results of a prospective randomized trial.  Arch Surg. 1995;  130 1062-1067
  • 353 Malila N, Virtamo J, Virtanen M. et al . Dietary and serum alpha-tocopherol, beta-carotene and retinol, and risk for colorectal cancer in male smokers.  Eur J Clin Nutr. 2002;  56 615-621
  • 354 Mandel J S, Bond J H, Church T R. et al . Reducing mortality from colorectal cancer by screening for fecal occult blood. Minnesota Colon Cancer Control Study.  N Engl J Med. 1993;  328 1365-1371
  • 355 Mandel J S, Church T R, Bond J H. et al . The effect of fecal occult-blood screening on the incidence of colorectal cancer.  N Engl J Med. 2000;  343 1603-1607
  • 356 Mandel J S, Church T R, Ederer F. et al . Colorectal cancer mortality: effectiveness of biennial screening for fecal occult blood.  J Natl Cancer Inst. 1999;  91 434-437
  • 357 Marchesa P, Lashner B A, Lavery I C. et al . The risk of cancer and dysplasia among ulcerative colitis patients with primary sclerosing cholangitis.  Am J Gastroenterol. 1997;  92 1285-1288
  • 358 Martinez M E, Heddens D, Earnest D L. et al . Physical activity, body mass index, and prostaglandin E2 levels in rectal mucosa.  J Natl Cancer Inst. 1999;  91 950-953
  • 359 Martinez M E, Sampliner R, Marshall J R. et al . Adenoma characteristics as risk factors for recurrence of advanced adenomas.  Gastroenterology. 2001;  120 1077-1083
  • 360 Marusch F, Gastinger I, Schneider C. et al . Importance of conversion for results obtained with laparoscopic colorectal surgery.  Dis Colon Rectum. 2001;  44 207-214
  • 361 Marusch F, Koch A, Schmidt U. et al . Importance of rectal extirpation for the therapy concept of low rectal cancers.  Chirurg. 2003;  74 341-351; discussion 351 - 352
  • 362 Mathur P, Smith J J, Ramsey C. et al . Comparison of CT and MRI in the pre-operative staging of rectal adenocarcinoma and prediction of circumferential resection margin involvement by MRI.  Colorectal Dis. 2003;  5 396-401
  • 363 Matsumoto T, Iida M, Nakamura S. et al . Natural history of ampullary adenoma in familial adenomatous polyposis: reconfirmation of benign nature during extended surveillance.  Am J Gastroenterol. 2000;  95 1557-1562
  • 364 Matsuo S, Eguchi S, Azuma T. et al . Attenuated familial adenomatous polyposis associated with advanced rectal cancer in a 16-year-old boy: report of a case.  Surg Today. 2001;  31 1020-1023
  • 365 Matsuoka H, Nakamura A, Masaki T. et al . A prospective comparison between multidetector-row computed tomography and magnetic resonance imaging in the preoperative evaluation of rectal carcinoma.  Am J Surg. 2003;  185 556-559
  • 366 Matzel K E, Merkel S, Hohenberger W. Lokale Therapieprinzipien beim Rektumkarzinom.  Chirurg. 2003;  74 897-904
  • 367 Maughan T S, James R D, Kerr D J. et al . Comparison of intermittent and continuous palliative chemotherapy for advanced colorectal cancer: a multicentre randomised trial.  Lancet. 2003;  361 457-464
  • 368 McAndrew M R, Saba A K. Efficacy of routine preoperative computed tomography scans in colon cancer.  Am Surg. 1999;  65 205-208
  • 369 McCall J L, Cox M R, Wattchow D A. Analysis of local recurrence rates after surgery alone for rectal cancer.  Int J Colorectal Dis. 1995;  10 126-132
  • 370 McFall M R, Woods W G, Miles W F. Colonoscopic surveillance after curative colorectal resection: results of an empirical surveillance programme.  Colorectal Dis. 2003;  5 233-240
  • 371 McGrath J S, Ponich T P, Gregor J C. Screening for colorectal cancer: the cost to find an advanced adenoma.  Am J Gastroenterol. 2002;  97 2902-2907
  • 372 McKelvey W, Greenland S, Sandler R S. A second look at the relation between colorectal adenomas and consumption of foods containing partially hydrogenated oils.  Epidemiology. 2000;  11 469-473
  • 373 Merkel S, Meyer T, Gohl J. et al . Late locoregional recurrence in rectal carcinoma.  Eur J Surg Oncol. 2002;  28 716-722
  • 374 Merkel S, Wein A, Gunther K. et al . High-risk groups of patients with Stage II colon carcinoma.  Cancer. 2001;  92 1435-1443
  • 375 Milsom J W, Bohm B, Hammerhofer K A. et al . A prospective, randomized trial comparing laparoscopic versus conventional techniques in colorectal cancer surgery: a preliminary report.  J Am Coll Surg. 1998;  187 46-54
  • 376 Minsky B D, Mies C, Recht A. et al . Resectable adenocarcinoma of the rectosigmoid and rectum. II. The influence of blood vessel invasion.  Cancer. 1988;  61 1417-1424
  • 377 Moertel C G, Fleming T R, Macdonald J S. et al . An evaluation of the carcinoembryonic antigen (CEA) test for monitoring patients with resected colon cancer.  Jama. 1993;  270 943-947
  • 378 Moertel C G, Fleming T R, Macdonald J S. et al . Intergroup study of fluorouracil plus levamisole as adjuvant therapy for stage II/Dukes’ B2 colon cancer.  J Clin Oncol. 1995;  13 2936-2943
  • 379 Moody G A, Jayanthi V, Probert C S. et al . Long-term therapy with sulphasalazine protects against colorectal cancer in ulcerative colitis: a retrospective study of colorectal cancer risk and compliance with treatment in Leicestershire.  Eur J Gastroenterol Hepatol. 1996;  8 1179-1183
  • 380 Moozar K L, Madlensky L, Berk T. et al . Slow progression of periampullary neoplasia in familial adenomatous polyposis.  J Gastrointest Surg. 2002;  6 831-837; discussion 837
  • 381 Muller A D, Sonnenberg A. Prevention of colorectal cancer by flexible endoscopy and polypectomy. A case-control study of 32,702 veterans.  Ann Intern Med. 1995;  123 904-910
  • 382 Muller A D, Sonnenberg A. Protection by endoscopy against death from colorectal cancer. A case-control study among veterans.  Arch Intern Med. 1995;  155 1741-1748
  • 383 Nakama H, Zhang B, Fukazawa K. et al . Family history of colorectal adenomatous polyps as a risk factor for colorectal cancer.  Eur J Cancer. 2000;  36 2111-2114
  • 384 Nanda K, Bastian L A, Hasselblad V. et al . Hormone replacement therapy and the risk of colorectal cancer: a meta-analysis.  Obstet Gynecol. 1999;  93 880-888
  • 385 Nelson H, Petrelli N, Carlin A. et al . Guidelines 2000 for colon and rectal cancer surgery.  J Natl Cancer Inst. 2001;  93 583-596
  • 386 Nelson H D, Humphrey L L, Nygren P. et al . Postmenopausal hormone replacement therapy: scientific review.  Jama. 2002;  288 872-881
  • 387 Neri E, Giusti P, Battolla L. et al . Colorectal cancer: role of CT colonography in preoperative evaluation after incomplete colonoscopy.  Radiology. 2002;  223 615-619
  • 388 Netzer P, Forster C, Biral R. et al . Risk factor assessment of endoscopically removed malignant colorectal polyps.  Gut. 1998;  43 669-674
  • 389 Neugut A I, Jacobson J S, Ahsan H. et al . Incidence and recurrence rates of colorectal adenomas: a prospective study.  Gastroenterology. 1995;  108 402-408
  • 390 Newcomb P A, Norfleet R G, Storer B E. et al . Screening sigmoidoscopy and colorectal cancer mortality.  J Natl Cancer Inst. 1992;  84 1572-1575
  • 391 Newcomb P A, Storer B E, Morimoto L M. et al . Long-term efficacy of sigmoidoscopy in the reduction of colorectal cancer incidence.  J Natl Cancer Inst. 2003;  95 622-625
  • 392 Nitti D, Wils J, Sahmoud T. et al . Final results of a phase III clinical trial on adjuvant intraportal infusion with heparin and 5-fluorouracil (5-FU) in resectable colon cancer (EORTC GITCCG 1983 - 1987). European Organization for Research and Treatment of Cancer. Gastrointestinal Tract Cancer Cooperative Group.  Eur J Cancer. 1997;  33 1209-1215
  • 393 Nivatvongs S. Complications in colonoscopic polypectomy. An experience with 1,555 polypectomies.  Dis Colon Rectum. 1986;  29 825-830
  • 394 Norat T, Lukanova A, Ferrari P. et al . Meat consumption and colorectal cancer risk: dose-response meta-analysis of epidemiological studies.  Int J Cancer. 2002;  98 241-256
  • 395 Normen A L, Brants H A, Voorrips L E. et al . Plant sterol intakes and colorectal cancer risk in the Netherlands Cohort Study on Diet and Cancer.  Am J Clin Nutr. 2001;  74 141-148
  • 396 Norton I D, Gostout C J, Baron T H. et al . Safety and outcome of endoscopic snare excision of the major duodenal papilla.  Gastrointest Endosc. 2002;  56 239-243
  • 397 Norton S A, Thomas M G. Staging of rectosigmoid neoplasia with colonoscopic endoluminal ultrasonography.  Br J Surg. 1999;  86 942-946
  • 398 Norum J. Prevention of colorectal cancer: a cost-effectiveness approach to a screening model employing sigmoidoscopy.  Ann Oncol. 1998;  9 613-618
  • 399 Noshirwani K C, van Stolk R U, Rybicki L A. et al . Adenoma size and number are predictive of adenoma recurrence: implications for surveillance colonoscopy.  Gastrointest Endosc. 2000;  51 433-437
  • 400 Nuako K W, Ahlquist D A, Mahoney D W. et al . Familial predisposition for colorectal cancer in chronic ulcerative colitis: a case-control study.  Gastroenterology. 1998;  115 1079-1083
  • 401 Nuako K W, Ahlquist D A, Sandborn W J. et al . Primary sclerosing cholangitis and colorectal carcinoma in patients with chronic ulcerative colitis: a case-control study.  Cancer. 1998;  82 822-826
  • 402 Nusko G, Mansmann U, Altendorf-Hofmann A. et al . Risk of invasive carcinoma in colorectal adenomas assessed by size and site.  Int J Colorectal Dis. 1997;  12 267-271
  • 403 Nusko G, Mansmann U, Kirchner T. et al . Risk related surveillance following colorectal polypectomy.  Gut. 2002;  51 424-428
  • 404 Nyam D C, Brillant P T, Dozois R R. et al . Ileal pouch-anal canal anastomosis for familial adenomatous polyposis: early and late results.  Ann Surg. 1997;  226 514-519; discussion 519 - 521
  • 405 O’Brien M J, Winawer S J, Zauber A G. et al . The National Polyp Study. Patient and polyp characteristics associated with high-grade dysplasia in colorectal adenomas.  Gastroenterology. 1990;  98 371-379
  • 406 O’Connell M J, Mailliard J A, Kahn M J. et al . Controlled trial of fluorouracil and low-dose leucovorin given for 6 months as postoperative adjuvant therapy for colon cancer.  J Clin Oncol. 1997;  15 246-250
  • 407 O’Connell M J, Martenson J A, Wieand H S. et al . Improving adjuvant therapy for rectal cancer by combining protracted-infusion fluorouracil with radiation therapy after curative surgery.  N Engl J Med. 1994;  331 502-507
  • 408 Ohlsson B, Breland U, Ekberg H. et al . Follow-up after curative surgery for colorectal carcinoma. Randomized comparison with no follow-up.  Dis Colon Rectum. 1995;  38 619-626
  • 409 Okuyama T, Oya M, Ishikawa H. Budding as a risk factor for lymph node metastasis in pT1 or pT2 well-differentiated colorectal adenocarcinoma.  Dis Colon Rectum. 2002;  45 628-634
  • 410 Orrom W J, Wong W D, Rothenberger D A. et al . Endorectal ultrasound in the preoperative staging of rectal tumors. A learning experience.  Dis Colon Rectum. 1990;  33 654-659
  • 411 Otchy D P, Ransohoff D F, Wolff B G. et al . Metachronous colon cancer in persons who have had a large adenomatous polyp.  Am J Gastroenterol. 1996;  91 448-454
  • 412 Ozoux J P, de Calan L, Perrier M. et al . Surgery for carcinoma of the colon in people aged 75 years and older.  Int J Colorectal Dis. 1990;  5 25-30
  • 413 Papadopoulos N, Lindblom A. Molecular basis of HNPCC: mutations of MMR genes.  Hum Mut. 1997;  10 89-99
  • 414 Papagrigoriadis S, Heyman B. Patients’ views on follow up of colorectal cancer: implications for risk communication and decision making.  Postgrad Med J. 2003;  79 403-407
  • 415 Pappalardo G, Polettini E, Frattaroli F M. et al . Magnetic resonance colonography versus conventional colonoscopy for the detection of colonic endoluminal lesions.  Gastroenterology. 2000;  119 300-304
  • 416 Parc Y R, Moslein G, Dozois R R. et al . Familial adenomatous polyposis: results after ileal pouch-anal anastomosis in teenagers.  Dis Colon Rectum. 2000;  43 893-898; discussion 898 - 902
  • 417 Pardi D S, Loftus E V Jr, Kremers W K. et al . Ursodeoxycholic acid as a chemopreventive agent in patients with ulcerative colitis and primary sclerosing cholangitis.  Gastroenterology. 2003;  124 889-893
  • 418 Pedersen A, Johansen C, Gronbaek M. Relations between amount and type of alcohol and colon and rectal cancer in a Danish population based cohort study.  Gut. 2003;  52 861-867
  • 419 Persson P G, Karlen P, Bernell O. et al . Crohn’s disease and cancer: a population-based cohort study.  Gastroenterology. 1994;  107 1675-1679
  • 420 Peters U, Sinha R, Chatterjee N. et al . Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme.  Lancet. 2003;  361 1491-1495
  • 421 Petersen V C, Baxter K J, Love S B. et al . Identification of objective pathological prognostic determinants and models of prognosis in Dukes’ B colon cancer.  Gut. 2002;  51 65-69
  • 422 Pezim M E, Nicholls R J. Survival after high or low ligation of the inferior mesenteric artery during curative surgery for rectal cancer.  Ann Surg. 1984;  200 729-733
  • 423 Pickhardt P J, Choi J R, Hwang I. et al . Computed tomographic virtual colonoscopy to screen for colorectal neoplasia in asymptomatic adults.  N Engl J Med. 2003;  349 2191-2200
  • 424 Pietra N, Sarli L, Costi R. et al . Role of follow-up in management of local recurrences of colorectal cancer: a prospective, randomized study.  Dis Colon Rectum. 1998;  41 1127-1133
  • 425 Pietra N, Sarli L, Thenasseril B J. et al . Risk factors of local recurrence of colorectal cancer: a multivariate study.  Hepatogastroenterology. 1998;  45 1573-1578
  • 426 Pignone M, Campbell M K, Carr C. et al . Meta-analysis of dietary restriction during fecal occult blood testing.  Eff Clin Pract. 2001;  4 150-156
  • 427 Pignone M, Saha S, Hoerger T. et al . Cost-effectiveness analyses of colorectal cancer screening: a systematic review for the U.S. Preventive Services Task Force.  Ann Intern Med. 2002;  137 96-104
  • 428 Pilipshen S J, Heilweil M, Quan S H. et al . Patterns of pelvic recurrence following definitive resections of rectal cancer.  Cancer. 1984;  53 1354-1362
  • 429 Pinczowski D, Ekbom A, Baron J. et al . Risk factors for colorectal cancer in patients with ulcerative colitis: a case-control study.  Gastroenterology. 1994;  107 117-120
  • 430 Popescu R A, Norman A, Ross P J. et al . Adjuvant or palliative chemotherapy for colorectal cancer in patients 70 years or older.  J Clin Oncol. 1999;  17 2412-2418
  • 431 Porschen R, Bermann A, Loffler T. et al . Fluorouracil plus leucovorin as effective adjuvant chemotherapy in curatively resected stage III colon cancer: results of the trial adjCCA-01.  J Clin Oncol. 2001;  19 1787-1794
  • 432 Poulin E C, Schlachta C M, Gregoire R. et al . Local recurrence and survival after laparoscopic mesorectal resection forrectal adenocarcinoma.  Surg Endosc. 2002;  16 989-995
  • 433 Prihartono N, Palmer J R, Louik C. et al . A case-control study of use of postmenopausal female hormone supplements in relation to the risk of large bowel cancer.  Cancer Epidemiol Biomarkers Prev. 2000;  9 443-447
  • 434 Prorok P C, Andriole G L, Bresalier R S. et al . Design of the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial.  Control Clin Trials. 2000;  21 273S-309S
  • 435 Provenzale D, Garrett J W, Condon S E. et al . Risk for colon adenomas in patients with rectosigmoid hyperplastic polyps.  Ann Intern Med. 1990;  113 760-763
  • 436 Provenzale D, Kowdley K V, Arora S. et al . Prophylactic colectomy or surveillance for chronic ulcerative colitis? A decision analysis.  Gastroenterology. 1995;  109 1188-1196
  • 437 Punt C J, Nagy A, Douillard J Y. et al . Edrecolomab alone or in combination with fluorouracil and folinic acid in the adjuvant treatment of stage III colon cancer: a randomised study.  Lancet. 2002;  360 671-677
  • 438 Quirke P. Training and quality assurance for rectal cancer: 20 years of data is enough.  Lancet Oncol. 2003;  4 695-702
  • 439 Rasmussen M, Kronborg O, Fenger C. et al . Possible advantages and drawbacks of adding flexible sigmoidoscopy to hemoccult-II in screening for colorectal cancer. A randomized study.  Scand J Gastroenterol. 1999;  34 73-78
  • 440 Ratto C, Sofo L, Ippoliti M. et al . Accurate lymph-node detection in colorectal specimens resected for cancer is of prognostic significance.  Dis Colon Rectum. 1999;  42 143-154
  • 441 Read T E, Read J D, Butterly L F. Importance of adenomas 5 mm or less in diameter that are detected by sigmoidoscopy.  N Engl J Med. 1997;  336 8-12
  • 442 Reid J D. Intestinal carcinoma in the Peutz-Jeghers syndrome.  Jama. 1974;  229 833-834
  • 443 Reid M E, Marshall J R, Roe D. et al . Smoking exposure as a risk factor for prevalent and recurrent colorectal adenomas.  Cancer Epidemiol Biomarkers Prev. 2003;  12 1006-1011
  • 444 Reiertsen O, Skjoto J, Jacobsen C D. et al . Complications of fiberoptic gastrointestinal endoscopy - five years’ experience in a central hospital.  Endoscopy. 1987;  19 1-6
  • 445 Renaut A J, Douglas P R, Newstead G L. Hyperplastic polyposis of the colon and rectum.  Colorectal Dis. 2002;  4 213-215
  • 446 Renehan A G, Egger M, Saunders M P. et al . Impact on survival of intensive follow up after curative resection for colorectal cancer: systematic review and meta-analysis of randomised trials.  Bmj. 2002;  324 813
  • 447 Renkonen-Sinisalo L, Aarnio M, Mecklin J P. et al . Surveillance improves survival of colorectal cancer in patients with hereditary nonpolyposis colorectal cancer.  Cancer Detect Prev. 2000;  24 137-142
  • 448 Renkonen-Sinisalo L, Sipponen P, Aarnio M. et al . No support for endoscopic surveillance for gastric cancer in hereditary non-polyposis colorectal cancer.  Scand J Gastroenterol. 2002;  37 574-577
  • 449 Rex D K. Postpolypectomy and post-cancer resection surveillance.  Rev Gastroenterol Disord. 2003;  3 202-209
  • 450 Rex D K, Chak A, Vasudeva R. et al . Prospective determination of distal colon findings in average-risk patients with proximal colon cancer.  Gastrointest Endosc. 1999;  49 727-730
  • 451 Rex D K, Cummings O W, Helper D J. et al . 5-year incidence of adenomas after negative colonoscopy in asymptomatic average-risk persons [see comment].  Gastroenterology. 1996;  111 1178-1181
  • 452 Rex D K, Cutler C S, Lemmel G T. et al . Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies.  Gastroenterology. 1997;  112 24-28
  • 453 Rex D K, Rahmani E Y, Haseman J H. et al . Relative sensitivity of colonoscopy and barium enema for detection of colorectal cancer in clinical practice.  Gastroenterology. 1997;  112 17-23
  • 454 Rex D K, Smith J J, Ulbright T M. et al . Distal colonic hyperplastic polyps do not predict proximal adenomas in asymptomatic average-risk subjects.  Gastroenterology. 1992;  102 317-319
  • 455 Rex D K, Vining D, Kopecky K K. An initial experience with screening for colon polyps using spiral CT with and without CT colography (virtual colonoscopy).  Gastrointest Endosc. 1999;  50 309-313
  • 456 Reynolds J V, Joyce W P, Dolan J. et al . Pathological evidence in support of total mesorectal excision in the management of rectal cancer.  Br J Surg. 1996;  83 1112-1115
  • 457 Rocklin M S, Slomski C A, Watne A L. Postoperative surveillance of patients with carcinoma of the colon and rectum.  Am Surg. 1990;  56 22-27
  • 458 Rodel C, Grabenbauer G G, Schick C. et al . Preoperative radiation with concurrent 5-fluorouracil for locally advanced T4-primary rectal cancer.  Strahlenther Onkol. 2000;  176 161-167
  • 459 Rodriguez-Bigas M A, Boland C R, Hamilton S R. et al . A National Cancer Institute Workshop on Hereditary Nonpolyposis Colorectal Cancer Syndrome: meeting highlights and Bethesda guidelines.  J Natl Cancer Inst. 1997;  89 1758-1762
  • 460 Rodriguez-Bigas M A, Vasen H F, Lynch H T. et al . Characteristics of small bowel carcinoma in hereditary nonpolyposis colorectal carcinoma. International Collaborative Group on HNPCC.  Cancer. 1998;  83 240-244
  • 461 Rosen M, Chan L, Beart R W Jr. et al . Follow-up of colorectal cancer: a meta-analysis.  Dis Colon Rectum. 1998;  41 1116-1126
  • 462 Ross P, Norman A, Cunningham D. et al . A prospective randomised trial of protracted venous infusion 5-fluorouracil with or without mitomycin C in advanced colorectal cancer.  Ann Oncol. 1997;  8 995-1001
  • 463 Rothenberg M L, Oza A M, Bigelow R H. et al . Superiority of oxaliplatin and fluorouracil-leucovorin compared with either therapy alone in patients with progressive colorectal cancer after irinotecan and fluorouracil-leucovorin: interim results of a phase III trial.  J Clin Oncol. 2003;  21 2059-2069
  • 464 Rouffet F, Hay J M, Vacher B. et al . Curative resection for left colonic carcinoma: hemicolectomy vs. segmental colectomy. A prospective, controlled, multicenter trial. French Association for Surgical Research.  Dis Colon Rectum. 1994;  37 651-659
  • 465 Rougier P, Cutsem E V, Bajetta E. et al . Randomised trial of irinotecan versus fluorouracil by continuous infusion after fluorouracil failure in patients with metastatic colorectal cancer.  Lancet. 1998;  352 1407-1412
  • 466 Rougier P, Sahmoud T, Nitti D. et al . Adjuvant portal-vein infusion of fluorouracil and heparin in colorectal cancer: a randomised trial. European Organisation for Research and Treatment of Cancer Gastrointestinal Tract Cancer Cooperative Group, the Gruppo Interdisciplinare Valutazione Interventi in Oncologia, and the Japanese Foundation for Cancer Research.  Lancet. 1998;  351 1677-1681
  • 467 Rozen P, Fireman Z, Figer A. et al . Family history of colorectal cancer as a marker of potential malignancy within a screening programm.  Cancer. 1987;  60 248-254
  • 468 Rozen P, Knaani J, Samuel Z. Eliminating the need for dietary restrictions when using a sensitive guaiac fecal occult blood test.  Dig Dis Sci. 1999;  44 756-760
  • 469 Rozen P, Knaani J, Samuel Z. Comparative screening with a sensitive guaiac and specific immunochemical occult blood test in an endoscopic study.  Cancer. 2000;  89 46-52
  • 470 Rozen P, Samuel Z, Brazowski E. A prospective study of the clinical, genetic, screening, and pathologic features of a family with hereditary mixed polyposis syndrome.  Am J Gastroenterol. 2003;  98 2317-2320
  • 471 Rubin C E, Haggitt R C, Burmer G C. et al . DNA aneuploidy in colonic biopsies predicts future development of dysplasia in ulcerative colitis.  Gastroenterology. 1992;  103 1611-1620
  • 472 Rubin P H, Friedman S, Harpaz N. et al . Colonoscopic polypectomy in chronic colitis: conservative management after endoscopic resection of dysplastic polyps.  Gastroenterology. 1999;  117 1295-1300
  • 473 Safi F, Beyer H G. The value of follow-up after curative surgery of colorectal carcinoma.  Cancer Detect Prev. 1993;  17 417-424
  • 474 Saltz L B, Cox J V, Blanke C. et al . Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. Irinotecan Study Group.  N Engl J Med. 2000;  343 905-914
  • 475 Sandler R S, Halabi S, Baron J A. et al . A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer.  N Engl J Med. 2003;  348 883-890
  • 476 Sargent D J, Goldberg R M, Jacobson S D. et al . A pooled analysis of adjuvant chemotherapy for resected colon cancer in elderly patients.  N Engl J Med. 2001;  345 1091-1097
  • 477 Sassatelli R, Bertoni G, Serra L. et al . Generalized juvenile polyposis with mixed pattern and gastric cancer.  Gastroenterology. 1993;  104 910-915
  • 478 Sauer R. Adjuvant versus neoadjuvant combined modality treatment for locally advanced rectal cancer: first results of the German rectal cancer study (CAO/ARO/AIO-94).  Int J Radiat Oncol Biol Phys. 2003;  57 S124-125
  • 479 Saurin J C, Gutknecht C, Napoleon B. et al . Surveillance of duodenal adenomas in familial adenomatous polyposis reveals high cumulative risk of advanced disease.  J Clin Oncol. 2004;  22 493-498
  • 480 Saurin J C, Ligneau B, Ponchon T. et al . The influence of mutation site and age on the severity of duodenal polyposis in patients with familial adenomatous polyposis.  Gastrointest Endosc. 2002;  55 342-347
  • 481 Schiedeck T H, Schwandner O, Baca I. et al . Laparoscopic surgery for the cure of colorectal cancer: results of a German five-center study.  Dis Colon Rectum. 2000;  43 1-8
  • 482 Schloss I, Kidd M S, Tichelaar H Y. et al . Dietary factors associated with a low risk of colon cancer in coloured west coast fishermen.  S Afr Med J. 1997;  87 152-158
  • 483 Schoeggl A, Kitz K, Reddy M. et al . Stereotactic radiosurgery for brain metastases from colorectal cancer.  Int J Colorectal Dis. 2002;  17 150-155
  • 484 Schoemaker D, Black R, Giles L. et al . Yearly colonoscopy, liver CT, and chest radiography do not influence 5-year survival of colorectal cancer patients.  Gastroenterology. 1998;  114 7-14
  • 485 Schoen R E. Surveillance after positive and negative colonoscopy examinations: issues, yields, and use.  Am J Gastroenterol. 2003;  98 1237-1246
  • 486 Schoen R E, Corle D, Cranston L. et al . Is colonoscopy needed for the nonadvanced adenoma found on sigmoidoscopy? The Polyp Prevention Trial.  Gastroenterology. 1998;  115 533-541
  • 487 Schoen R E, Pinsky P F, Weissfeld J L. et al . Results of repeat sigmoidoscopy 3 years after a negative examination.  Jama. 2003;  290 41-48
  • 488 Scholefield J H, Moss S, Sufi F. et al . Effect of faecal occult blood screening on mortality from colorectal cancer: results from a randomised controlled trial.  Gut. 2002;  50 840-844
  • 489 Scholmerich J. [Sense and nonsense in after-care of colorectal carcinoma].  Med Klin (Munich). 1996;  91 420-427
  • 490 Schrag D, Rifas-Shiman S, Saltz L. et al . Adjuvant chemotherapy use for Medicare beneficiaries with stage II colon cancer.  J Clin Oncol. 2002;  20 3999-4005
  • 491 Schwibbe G. [Changes in quality of life in oncological patients in the course of an inpatient after-care program].  Rehabilitation (Stuttg). 1991;  30 55-62
  • 492 Sciallero S, Costantini M, Bertinelli E. et al . Distal hyperplastic polyps do not predict proximal adenomas: results from a multicentric study of colorectal adenomas.  Gastrointest Endosc. 1997;  46 124-130
  • 493 Scott N, Jackson P, al-Jaberi T. et al . Total mesorectal excision and local recurrence: a study of tumour spread in the mesorectum distal to rectal cancer.  Br J Surg. 1995;  82 1031-1033
  • 494 Secco G B, Fardelli R, Gianquinto D. et al . Factors influencing incidence and extension of metachronous liver metastases of colorectal adenocarcinoma. A multivariate analysis.  Hepatogastroenterology. 1997;  44 1057-1062
  • 495 Secco G B, Fardelli R, Gianquinto D. et al . Efficacy and cost of risk-adapted follow-up in patients after colorectal cancer surgery: a prospective, randomized and controlled trial.  Eur J Surg Oncol. 2002;  28 418-423
  • 496 Segnan N, Senore C, Andreoni B. et al . Baseline findings of the Italian multicenter randomized controlled trial of „once-only sigmoidoscopy” - SCORE.  J Natl Cancer Inst. 2002;  94 1763-1772
  • 497 Selby J V, Friedman G D, Quesenberry C P Jr. et al . A case-control study of screening sigmoidoscopy and mortality from colorectal cancer.  N Engl J Med. 1992;  326 653-657
  • 498 Sengupta S, Tjandra J J. Local excision of rectal cancer: what is the evidence?.  Dis Colon Rectum. 2001;  44 1345-1361
  • 499 Shibata D, Paty P B, Guillem J G. et al . Surgical management of isolated retroperitoneal recurrences of colorectal carcinoma.  Dis Colon Rectum. 2002;  45 795-801
  • 500 Sieg A, Hachmoeller-Eisenbach U, Eisenbach T. Prospective evaluation of complications in outpatient GI endoscopy: a survey among German gastroenterologists.  Gastrointest Endosc. 2001;  53 620-627
  • 501 Sijmons R H, Kiemeney L A, Witjes J A. et al . Urinary tract cancer and hereditary nonpolyposis colorectal cancer: risks and screening options.  J Urol. 1998;  160 466-470
  • 502 Slanetz C A Jr, Grimson R. Effect of high and intermediate ligation on survival and recurrence rates following curative resection of colorectal cancer.  Dis Colon Rectum. 1997;  40 1205-1218
  • 503 Slattery M L, Levin T R, Ma K. et al . Family history and colorectal cancer: predictors of risk.  Cancer Causes Control. 2003;  14 879-887
  • 504 Sobin L H. TNM, sixth edition: new developments in general concepts and rules.  Semin Surg Oncol. 2003;  21 19-22
  • 505 Soetikno R M, Lin O S, Heidenreich P A. et al . Increased risk of colorectal neoplasia in patients with primary sclerosing cholangitis and ulcerative colitis: a meta-analysis.  Gastrointest Endosc. 2002;  56 48-54
  • 506 Solbiati L, Livraghi T, Goldberg S N. et al . Percutaneous radio-frequency ablation of hepatic metastases from colorectal cancer: long-term results in 117 patients.  Radiology. 2001;  221 159-166
  • 507 Sondergaard J O, Bulow S, Lynge E. Cancer incidence among parents of patients with colorectal cancer.  Int J Cancer. 1991;  47 202-206
  • 508 Sonnenberg A, Delco F. Cost-effectiveness of a single colonoscopy in screening for colorectal cancer.  Arch Intern Med. 2002;  162 163-168
  • 509 Soravia C, Berk T, Madlensky L. et al . Genotype-phenotype correlations in attenuated adenomatous polyposis coli.  Am J Hum Genet. 1998;  62 1290-1301
  • 510 Soravia C, Berk T, McLeod R S. et al . Desmoid disease in patients with familial adenomatous polyposis.  Dis Colon Rectum. 2000;  43 363-369
  • 511 Soreide O, Norstein J, Fielding L P. et al .International standardization and documentation of the treatment of rectal cancer. Soreide O, Norstein J Rectal cancer surgery. Optimisation - standardization - documentation Berlin/Heidelberg/New York; Springer 1997: 405-445
  • 512 Sosna J, Morrin M M, Kruskal J B. et al . CT colonography of colorectal polyps: a metaanalysis.  AJR Am J Roentgenol. 2003;  181 1593-1598
  • 513 Spigelman A D, Murday V, Phillips R K. Cancer and the Peutz-Jeghers syndrome.  Gut. 1989;  30 1588-1590
  • 514 Spigelman A D, Williams C B, Talbot I C. et al . Upper gastrointestinal cancer in patients with familial adenomatous polyposis.  Lancet. 1989;  2 783-785
  • 515 St John D J, McDermott F T, Hopper J L. et al . Cancer risk in relatives of patients with common colorectal cancer.  Ann Int Med. 1993;  118 785-790
  • 516 Stefansson T, Ekborm A, Sparen P. et al . Cancers among patients diagnosed as having diverticular disease of the colon.  Eur J Surg. 1995;  161 755-760
  • 517 Steinbach G, Lynch P M, Phillips R K. et al . The effect of celecoxib, a cyclooxygenase-2 inhibitor, in familial adenomatous polyposis.  N Engl J Med. 2000;  342 1946-1952
  • 518 Stevens T, Burke C A. Colonoscopy screening in the elderly: when to stop?.  Am J Gastroenterol. 2003;  98 1881-1885
  • 519 Sturmer T, Glynn R J, Lee I M. et al . Aspirin use and colorectal cancer: post-trial follow-up data from the Physicians’ Health Study.  Ann Intern Med. 1998;  128 713-720
  • 520 Sugarbaker P H, Gianola F J, Dwyer A. et al . A simplified plan for follow-up of patients with colon and rectal cancer supported by prospective studies of laboratory and radiologic test results.  Surgery. 1987;  102 79-87
  • 521 Surtees P, Ritchie J K, Phillips R K. High versus low ligation of the inferior mesenteric artery in rectal cancer.  Br J Surg. 1990;  77 618-621
  • 522 Swanson R S, Compton C C, Stewart A K. et al . The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined.  Ann Surg Oncol. 2003;  10 65-71
  • 523 Syrigos K N, Charalampopoulos A, Ho J L. et al . Colonoscopy in asymptomatic individuals with a family history of colorectal cancer.  Ann Surg Oncol. 2002;  9 439-443
  • 524 Taal B G, Van Tinteren H, Zoetmulder F A. Adjuvant 5FU plus levamisole in colonic or rectal cancer: improved survival in stage II and III.  Br J Cancer. 2001;  85 1437-1443
  • 525 Tagore K S, Lawson M J, Yucaitis J A. et al . Sensitivity and specificity of a stool DNA multitarget assay panel for the detection of advanced colorectal neoplasia.  Clin Colorectal Cancer. 2003;  3 47-53
  • 526 Takahashi T, Kato T, Kodaira S. et al . Prognostic factors of colorectal cancer. Results of multivariate analysis of curative resection cases with or without adjuvant chemotherapy.  Am J Clin Oncol. 1996;  19 408-415
  • 527 Takeshita T, Morimoto K, Yamaguchi N. et al . Relationships between cigarette smoking, alcohol drinking, the ALDH2 genotype and adenomatous types of colorectal polyps in male self-defense force officials.  J Epidemiol. 2000;  10 366-371
  • 528 Talbot I C, Ritchie S, Leighton M H. et al . The clinical significance of invasion of veins by rectal cancer.  Br J Surg. 1980;  67 439-442
  • 529 Tejero E, Fernandez-Lobato R, Mainar A. et al . Initial results of a new procedure for treatment of malignant obstruction of the left colon.  Dis Colon Rectum. 1997;  40 432-436
  • 530 Tepper J E, O’Connell M, Niedzwiecki D. et al . Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control - final report of intergroup 0114.  J Clin Oncol. 2002;  20 1744-1750
  • 531 Terry M B, Neugut A I. Cigarette smoking and the colorectal adenoma-carcinoma sequence: a hypothesis to explain the paradox.  Am J Epidemiol. 1998;  147 903-910
  • 532 Terry M B, Neugut A I, Bostick R M. et al . Risk factors for advanced colorectal adenomas: a pooled analysis.  Cancer Epidemiol Biomarkers Prev. 2002;  11 622-629
  • 533 Terry P, Giovannucci E, Michels K B. et al . Fruit, vegetables, dietary fiber, and risk of colorectal cancer.  J Natl Cancer Inst. 2001;  93 525-533
  • 534 Thaler W, Watzka S, Martin F. et al . Preoperative staging of rectal cancer by endoluminal ultrasound vs. magnetic resonance imaging. Preliminary results of a prospective, comparative study.  Dis Colon Rectum. 1994;  37 1189-1193
  • 535 Thiis-Evensen E, Hoff G S, Sauar J. et al . Population-based surveillance by colonoscopy: effect on the incidence of colorectal cancer. Telemark Polyp Study I.  Scand J Gastroenterol. 1999;  34 414-420
  • 536 Thomas D, Pritchard J, Davidson R. et al . Familial hepatoblastoma and APC gene mutations: renewed call for molecular research.  Eur J Cancer. 2003;  39 2200-2204
  • 537 Thompson-Fawcett M W, Marcus V, Redston M. et al . Risk of dysplasia in long-term ileal pouches and pouches with chronic pouchitis.  Gastroenterology. 2001;  121 275-281
  • 538 Tiemersma E W, Wark P A, Ocke M C. et al . Alcohol consumption, alcohol dehydrogenase 3 polymorphism, and colorectal adenomas.  Cancer Epidemiol Biomarkers Prev. 2003;  12 419-425
  • 539 Tournigand C, Andre T, Achille E. et al . FOLFIRI followed by FOLFOX6 or the reverse sequence in advanced colorectal cancer: a randomized GERCOR study.  J Clin Oncol. 2004;  22 229-237
  • 540 Towler B, Irwig L, Glasziou P. et al . A systematic review of the effects of screening for colorectal cancer using the faecal occult blood test, hemoccult.  Bmj. 1998;  317 559-565
  • 541 Traverso G, Shuber A, Levin B. et al . Detection of APC mutations in fecal DNA from patients with colorectal tumors.  N Engl J Med. 2002;  346 311-320
  • 542 Truta B, Allen B A, Conrad P G. et al . Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinoma.  Fam Cancer. 2003;  2 95-99
  • 543 Tsuda S, Veress B, Toth E. et al . Flat and depressed colorectal tumours in a southern Swedish population: a prospective chromoendoscopic and histopathological study.  Gut. 2002;  51 550-555
  • 544 Turegano-Fuentes F, Echenagusia-Belda A, Simo-Muerza G. et al . Transanal self-expanding metal stents as an alternative to palliative colostomy in selected patients with malignant obstruction of the left colon.  Br J Surg. 1998;  85 232-235
  • 545 Tveit K M, Guldvog I, Hagen S. et al . Randomized controlled trial of postoperative radiotherapy and short-term time-scheduled 5-fluorouracil against surgery alone in the treatment of Dukes B and C rectal cancer. Norwegian Adjuvant Rectal Cancer Project Group.  Br J Surg. 1997;  84 1130-1135
  • 546 UICC. TNM Classification of Malignant Tumours. New York: John Wiley & Sons, 2002. 
  • 547 Ullman T, Croog V, Harpaz N. et al . Progression of flat low-grade dysplasia to advanced neoplasia in patients with ulcerative colitis.  Gastroenterology. 2003;  125 1311-1319
  • 548 Ullman T A, Loftus E V Jr, Kakar S. et al . The fate of low grade dysplasia in ulcerative colitis.  Am J Gastroenterol. 2002;  97 922-927
  • 549 Umar A, Boland C R, Terdiman J P. et al . Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability.  J Natl Cancer Inst. 2004;  96 261-268
  • 550 Van Cutsem E, Twelves C, Cassidy J. et al . Oral capecitabine compared with intravenous fluorouracil plus leucovorin in patients with metastatic colorectal cancer: results of a large phase III study.  J Clin Oncol. 2001;  19 4097-4106
  • 551 Van Damme J P. Vascular anatomy in abdominal surgery. Stuttgart; Thieme 1990
  • 552 Van Duijvendijk P, Slors J F, Taat C W. et al . Quality of life after total colectomy with ileorectal anastomosis or proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis.  Br J Surg. 2000;  87 590-596
  • 553 van Stolck R U, Beck G J, Baron J A. et al . Adenoma characteristics at first colonoscopy as predictors of adenoma recurrence and characteristics at follow-up. The Polyp Prevention Study Group.  Gastroenterology. 1998;  115 13-18
  • 554 Vasen H F, Bülow S, Myrhøj T. et al . Decision analysis in the management of duodenal adenomatosis in familial adenomatous polyposis.  Gut. 1997;  40 716-719
  • 555 Vasen H F, Mecklin J P, Khan P M. et al . The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC).  Dis Colon Rectum. 1991;  34 424-425
  • 556 Vasen H F, Sanders E A, Taal B G. et al . The risk of brain tumours in hereditary non-polyposis colorectal cancer (HNPCC).  Int J Cancer. 1996;  65 422-425
  • 557 Vasen H F, Stormorken A, Menko F H. et al . MSH2 mutation carriers are at higher risk of cancer than MLH1 mutation carriers: a study of hereditary nonpolyposis colorectal cancer families.  J Clin Oncol. 2001;  19 4074-4080
  • 558 Vasen H F, van Duijvendijk P, Buskens E. et al . Decision analysis in the surgical treatment of patients with familial adenomatous polyposis: a Dutch-Scandinavian collaborative study including 659 patients.  Gut. 2001;  49 231-235
  • 559 Vasen H F, Watson P, Mecklin J P. et al . The epidemiology of endometrial cancer in hereditary nonpolyposis colorectal cancer.  Anticancer Res. 1994;  14 1675-1678
  • 560 Vasen H F, Watson P, Mecklin J P. et al . New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative group on HNPCC.  Gastroenterology. 1999;  116 1453-1456
  • 561 Verne J E, Aubrey R, Love S B. et al . Population based randomized study of uptake and yield of screening by flexible sigmoidoscopy compared with screening by faecal occult blood testing.  Bmj. 1998;  317 182-185
  • 562 Vider B Z, Zimber A, Chastre E. et al . Evidence for the involvement of the Wnt 2 gene in human colorectal cancer.  Oncogene. 1996;  12 153-158
  • 563 Vieth M, Behrens H, Stolte M. [Sporadic adenoma and colitis-associated intraepithelial neoplasia: a difficult differential diagnosis].  Pathologe. 2003;  24 36-43
  • 564 Vijan S, Hwang E W, Hofer T P. et al . Which colon cancer screening test? A comparison of costs, effectiveness, and compliance.  Am J Med. 2001;  111 593-601
  • 565 Vogl T J, Straub R, Eichler K. et al . Malignant liver tumors treated with MR imaging-guided laser-induced thermotherapy: experience with complications in 899 patients (2,520 lesions).  Radiology. 2002;  225 367-377
  • 566 Voskuil D W, Kampman E, Grubben M J. et al . Meat consumption and meat preparation in relation to colorectal adenomas among sporadic and HNPCC family patients in The Netherlands.  Eur J Cancer. 2002;  38 2300-2308
  • 567 Wallace M B, Kemp J A, Trnka Y M. et al . Is colonoscopy indicated for small adenomas found by screening flexible sigmoidoscopy?.  Ann Intern Med. 1998;  129 273-278
  • 568 Wallis F, Campbell K L, Eremin O. et al . Self-expanding metal stents in the management of colorectal carcinoma - a preliminary report.  Clin Radiol. 1998;  53 251-254
  • 569 Watanabe A, Nagashima H, Motoi M. et al . Familial juvenile polyposis of the stomach.  Gastroenterology. 1979;  77 148-151
  • 570 Watson P, Lynch H T. Extracolonic cancer in hereditary nonpolyposis colorectal cancer.  Cancer. 1993;  71 677-685
  • 571 Waye J D, Kahn O, Auerbach M E. Complications of colonoscopy and flexible sigmoidoscopy.  Gastrointest Endosc Clin N Am. 1996;  6 343-377
  • 572 Waye J D, Lewis B S, Frankel A. et al . Small colon polyps.  Am J Gastroenterol. 1988;  83 120-122
  • 573 Waye J D, Lewis B S, Yessayan S. Colonoscopy: a prospective report of complications.  J Clin Gastroenterol. 1992;  15 347-351
  • 574 Weeks J C, Nelson H, Gelber S. et al . Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial.  Jama. 2002;  287 321-328
  • 575 Wei E K, Giovannucci E, Wu K. et al . Comparison of risk factors for colon and rectal cancer.  Int J Cancer. 2004;  108 433-442
  • 576 Wein A, Riedel C, Bruckl W. et al . Neoadjuvant treatment with weekly high-dose 5-Fluorouracil as 24-hour infusion, folinic acid and oxaliplatin in patients with primary resectable liver metastases of colorectal cancer.  Oncology. 2003;  64 131-138
  • 577 Wichmann M W, Muller C, Hornung H M. et al . Results of long-term follow-up after curative resection of Dukes A colorectal cancer.  World J Surg. 2002;  26 732-736
  • 578 Wiggers T, Jeekel J, Arends J W. et al . No-touch isolation technique in colon cancer: a controlled prospective trial.  Br J Surg. 1988;  75 409-415
  • 579 Winawer S, Fletcher R, Rex D. et al . Colorectal cancer screening and surveillance: clinical guidelines and rationale-Update based on new evidence.  Gastroenterology. 2003;  124 544-560
  • 580 Winawer S J, Flehinger B J, Schottenfeld D. et al . Screening for colorectal cancer with fecal occult blood testing and sigmoidoscopy.  J Natl Cancer Inst. 1993;  85 1311-1318
  • 581 Winawer S J, Fletcher R H, Miller L. et al . Colorectal cancer screening: clinical guidelines and rationale.  Gastroenterology. 1997;  112 594-642
  • 582 Winawer S J, O’Brien M J, Waye J D. et al . Risk and surveillance of individuals with colorectal polyps. WHO Collaborating Centre for the Prevention of Colorectal Cancer.  Bull World Health Organ. 1990;  68 789-795
  • 583 Winawer S J, Stewart E T, Zauber A G. et al . A comparison of colonoscopy and double-contrast barium enema for surveillance after polypectomy. National Polyp Study Work Group.  N Engl J Med. 2000;  342 1766-1772
  • 584 Winawer S J, Zauber A G, Gerdes H. et al . Risk of colorectal cancer in the families of patients with adenomatous polyps. National Polyp Study Workgroup.  N Engl J Med. 1996;  334 82-87
  • 585 Winawer S J, Zauber A G, Ho M N. et al . Prevention of colorectal cancer by colonoscopic polypectomy. The National Polyp Study Workgroup.  N Engl J Med. 1993;  329 1977-1981
  • 586 Winawer S J, Zauber A G, O’Brien M J. et al . Randomized comparison of surveillance intervals after colonoscopic removal of newly diagnosed adenomatous polyps. The National Polyp Study Workgroup.  N Engl J Med. 1993;  328 901-906
  • 587 Winde G, Nottberg H, Keller R. et al . Surgical cure for early rectal carcinomas (T1). Transanal endoscopic microsurgery vs. anterior resection.  Dis Colon Rectum. 1996;  39 969-976
  • 588 Winde G, Schmid K W, Schlegel W. et al . Complete reversion and prevention of rectal adenomas in colectomized patients with familial adenomatous polyposis by rectal low-dose sulindac maintenance treatment. Advantages of low-dose nonsteroidal anti-inflammatory drug regimen in reversing adenomas exceeding 33 months.  Dis Colon Rectum. 1995;  38 813-830
  • 589 Wittekind C, Compton C C, Greene F L. et al . TNM residual tumor classification revisited.  Cancer. 2002;  94 2511-2516
  • 590 Wittekind C, Tannapfel A. Regression grading of colorectal carcinoma after preoperative radiochemotherapy. An inventory.  Pathologe. 2003;  24 61-65
  • 591 Wolmark N, Rockette H, Mamounas E. et al . Clinical trial to assess the relative efficacy of fluorouracil and leucovorin, fluorouracil and levamisole, and fluorouracil, leucovorin, and levamisole in patients with Dukes’ B and C carcinoma of the colon: results from National Surgical Adjuvant Breast and Bowel Project C-04.  J Clin Oncol. 1999;  17 3553-3559
  • 592 Wolmark N, Wieand H S, Hyams D M. et al . Randomized trial of postoperative adjuvant chemotherapy with or without radiotherapy for carcinoma of the rectum: National Surgical Adjuvant Breast and Bowel Project Protocol R-02.  J Natl Cancer Inst. 2000;  92 388-396
  • 593 Wong J H, Severino R, Honnebier M B. et al . Number of nodes examined and staging accuracy in colorectal carcinoma.  J Clin Oncol. 1999;  17 2896-2900
  • 594 Wood N J, Duffy S R, Sheridan E. The outcome of endometrial carcinoma surveillance by ultrasound scan in women at risk of hereditary nonpolyposis colorectal carcinoma and familial colorectal carcinoma.  Cancer. 2003;  98 1772-1773; author reply 1773 - 1774
  • 595 Wu J S, Wong R, Johnston M. et al . Meta-analysis of dose-fractionation radiotherapy trials for the palliation of painful bone metastases.  Int J Radiat Oncol Biol Phys. 2003;  55 594-605
  • 596 Wu K, Willett W C, Chan J M. et al . A prospective study on supplemental vitamin e intake and risk of colon cancer in women and men.  Cancer Epidemiol Biomarkers Prev. 2002;  11 1298-1304
  • 597 Wu K, Willett W C, Fuchs C S. et al . Calcium intake and risk of colon cancer in women and men.  J Natl Cancer Inst. 2002;  94 437-446
  • 598 Yamazaki T, Takii Y, Okamoto H. et al . What is the risk factor for metachronous colorectal carcinoma?.  Dis Colon Rectum. 1997;  40 935-938
  • 599 Yoon H, Benamouzig R, Little J. et al . Systematic review of epidemiological studies on meat, dairy products and egg consumption and risk of colorectal adenomas.  Eur J Cancer Prev. 2000;  9 151-164
  • 600 Young G P, St John D J, Winawer S J. et al . Choice of fecal occult blood tests for colorectal cancer screening: recommendations based on performance characteristics in population studies: a WHO (World Health Organization) and OMED (World Organization for Digestive Endoscopy) report.  Am J Gastroenterol. 2002;  97 2499-2507
  • 601 Zacherl J, Scheuba C, Imhof M. et al . Current value of intraoperative sonography during surgery for hepatic neoplasms.  World J Surg. 2002;  26 550-554
  • 602 Zaheer S, Pemberton J H, Farouk R. et al . Surgical treatment of adenocarcinoma of the rectum.  Ann Surg. 1998;  227 800-811
  • 603 Zauber A, Winawer S J, Diaz B. et al . The national polyp study (NPS): the association of colonic hyperplastic polyps and adenomas.  Am J Gastroenterol. 1988;  83 1060
  • 604 Zauber A G, Winawer S J. Initial management and follow-up surveillance of patients with colorectal adenomas.  Gastroenterol Clin North Am. 1997;  26 85-101
  • 605 Zeng Z, Cohen A M, Urmacher C. Usefulness of carcinoembryonic antigen monitoring despite normal preoperative values in node-positive colon cancer patients.  Dis Colon Rectum. 1993;  36 1063-1068
  • 606 Z’Graggen K, Maurer C A, Birrer S. et al . A new surgical concept for rectal replacement after low anterior resection: the transverse coloplasty pouch.  Ann Surg. 2001;  234 780-785; discussion 785 - 787
  • 607 Z’Graggen K, Maurer C A, Buchler M W. The transverse coloplasty pouch. Review of experimental data and clinical application.  Zentralbl Chir. 2001;  126 (Suppl 1) 64-66
  • 608 Zhang B, Fattah A, Nakama H. Characteristics and survival rate of elderly patients with colorectal cancer detected by immunochemical occult blood screening.  Hepatogastroenterology. 2000;  47 414-418
  • 609 Zhang B, Li X, Nakama H. et al . A case-control study on risk of changing food consumption for colorectal cancer.  Cancer Invest. 2002;  20 458-463
  • 610 Zirngibl H, Husemann B, Hermanek P. Intraoperative spillage of tumor cells in surgery for rectal cancer.  Dis Colon Rectum. 1990;  33 610-614
  • 611 Zwick A, Munir M, Ryan C K. et al . Gastric adenocarcinoma and dysplasia in fundic gland polyps of a patient with attenuated adenomatous polyposis coli.  Gastroenterology. 1997;  113 659-663

1 1Krebsfrüherkennungsrichtlinien des Bundesausschusses der Ärzte und Krankenkassen in ihrer geltenden Fassung und in Verbindung mit der Qualitätssicherung nach § 135 Abs. 2 (veröffentlicht im Deutschen Ärzteblatt 2002)

Prof. Dr. W. Schmiegel

Ruhr-Universität Bochum, Medizinische Universitätsklinik, Knappschaftskrankenhaus

In der Schornau 23-25

44892 Bochum

Phone: + 49/2 34/2 99-34 01

Fax: + 49/2 34/2 99-34 09

Email: www.ruhr-uni-bochum.de/meduni-kkh


Und Abt. Gastroenterologie/Hepatologie, Universitätsklinik Bergmannsheil

Bürkle-de-la-Camp-Platz 1

44789 Bochum

Phone: +49/2 34/3 02-67 71

Fax: +49/2 34/3 02-67 07

Email: gastro-bergmannsheil@ruhr-uni-bochum.de

URL: http://www.bergmannsheil.degastro*Further correspondence on page 1177