Planta Med 2003; 69(3): 287-288
DOI: 10.1055/s-2003-38482
Letter
© Georg Thieme Verlag Stuttgart · New York

Isolation and X-Ray Study of an Anti-Inflammatory Active Androstene Steroid from Acacia nilotica

Rohini Chaubal1 , A. M. Mujumdar2 , Vedavati G. Puranik3 , V. H. Deshpande4 , N. R. Deshpande1
  • 1Post Graduate Research Centre, Department of Chemistry, Sir Parshurambhau College, Pune, India
  • 2Department of Botany, Agharkar Research Institute, Pune, India
  • 3Physical Chemistry Division, National Chemical Laboratory, Pune, India.
  • 4Organic Chemistry technology, National Chemical Laboratory, Pune, India.
Further Information

Publication History

Received: July 1, 2002

Accepted: November 16, 2002

Publication Date:
04 April 2003 (online)

Abstract

3β-Acetoxy-17β-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse earedema.

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N. R. Deshpande

Post Graduate Research Centre

Department of Chemistry

Sir Parshurambhau College

Pune 411 030

India