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Synlett 2002(2): 0307-0309
DOI: 10.1055/s-2002-19780
LETTER
© Georg Thieme Verlag Stuttgart · New York

Synthesis of 2-Oxazolidinones from CO2 and 1,2-Aminoalcohols Catalyzed by n-Bu2SnO

Ken-ichi Tominaga, Yoshiyuki Sasaki*
Research Institute for Green Technology, National Institute of Advanced Industrial Science and Technology (AIST), 16-1 Onogawa, Tsukuba, 305-8569, Japan
Fax: +81(298)618175; e-Mail: y.sasaki@aist.go.jp;
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Publication History

Received 5 November 2001
Publication Date:
02 February 2007 (online)

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Abstract

The dehydrative condensation of 1,2-aminoalcohols with CO2 is found to proceed in NMP as solvent; 2-oxazolidinones are obtained in the yields of 53-94% when a commercially available tin compound, n-Bu2SnO is used as catalyst.

Key words

carbon dioxide - aminoalcohols - oxazolidinone - tin - catalysis

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Positive ion ES mass spectra were recorded on a Waters ZQ-2000 mass spectrometer. The needle voltage was 3 kV and the drift voltage was 10 V. The CH3CN solution of the reaction solution (50 ppm) was introduced into the ES probe by syringe pomp.