Anästhesiol Intensivmed Notfallmed Schmerzther 2001; 36(Suppl 2): 121-122
DOI: 10.1055/s-2001-18203
ARTIFICIAL OXYGEN CARRIERS
ORIGINALIA
© Georg Thieme Verlag Stuttgart · New York

Clinical Update: Hemopure® -
A Room Temperature Stable
Hemoglobin Oxygen Carrier

Aktuelle Übersicht: Hemopure® -
Ein Raumtemperatur-stabiler Sauerstoffträger auf Hämoglobin-Basis
E. Jacobs
  • Biopure Corporation, Cambridge, MA., U.S.A.
Further Information

Publication History

Publication Date:
05 November 2001 (online)

Hemopure® (HBOC-201, hemoglobin glutamer - 250, bovine), a room temperature stable hemoglobin-based oxygen carrier requiring no typing or cross-matching, has been approved in South Africa for the treatment of surgical anemia in adults. The bovine derived polymerized hemoglobin (13 g/dL), in a balanced salt solution, is packaged in 250 ml flexible bag units for intravenous infusion. The product has a dose dependent plasma half-life of 24 to 36 hours, and has been shown in numerous preclinical and clinical studies to transport oxygen effectively.

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Edward Jacobs, M.D. 

Biopure Corp.

11 Hurley Street

Cambridge, MA 02141