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Planta Med 2000; 66(5): 485-486
DOI: 10.1055/s-2000-8585
DOI: 10.1055/s-2000-8585
Letter
Georg Thieme Verlag Stuttgart · New York
Cytotoxic Triterpenes from Stem Bark of Physocarpus intermedius
Further Information
Publication History
Publication Date:
31 December 2000 (online)
![](https://www.thieme-connect.de/media/plantamedica/200005/lookinside/thumbnails/10.1055-s-2000-8585-1.jpg)
Abstract
Seven triterpenes (1 - 7), i.e., betulinic acid 1, ursolic acid 2, oleanolic acid 3, 3-O-caffeoyloleanolic acid 4, euscaphic acid 5, 2α-hydroxyursolic acid 6 and maslinic acid 7 were isolated from the stem bark extract of P. intermedius as active principles responsible for the cytotoxicity against five cultured human tumor cell lines, i.e., A549 (non small cell lung), SK-OV-3 (ovary), SK-MEL-2 (melanoma), XF498 (central nerve system) and HCT-15 (colon), in vitro.
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Dr. Shi Yong Ryu
Korea Research Institute of Chemical Technology
Yusung P.O. Box 107
Taejeon
Korea 305-606
Email: syryu@pado.krict.re.kr
Phone: +82-42-861-1291
Fax: +82-42-860-7163