Planta Med 2000; 66(4): 377-379
DOI: 10.1055/s-2000-8550
Letter
Georg Thieme Verlag Stuttgart · New York

Evaluation of the Antiviral Activity of Kaempferol and its Glycosides Against Human Cytomegalovirus

Dimitra Mitrocotsa1 , Sofia Mitaku1,*, Stavros Axarlis2 , Catherine Harvala1 , Michalis Malamas3
  • 1 Division of Pharmacognosy, School of Pharmacy, University of Athens, Panepistimiopolis Zografou, Athens, Greece
  • 2 Hellenic Pasteur Institute, Athens, Greece
  • 3 Department of Pharmacology, Medical School, University of Ioannina, Ioannina, Greece
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Abstract

The antiviral activity of seven flavonoids, belonging to the kaempferol series, was evaluated against human cytomegalovirus (HCMV) by a rapid method of detection of the immediate-early (IE) antigen, induced by the virus in infected cells. Flavonoids bearing acyl substituents were found to be the most active compounds.

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Pr. S. Mitaku

Division of Pharmacognosy School of Pharmacy University of Athens

Panepistimiopolis Zografou

Athens 15771

Greece

Email: mitakou@pharm.uoa.gr

Phone: 017274594