Semin Musculoskelet Radiol 2000; 4(4): 459-480
DOI: 10.1055/s-2000-13171
Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: +1(212) 584-4662

Muscle Physiology and Pathophysiology: Magnetic Resonance Imaging Evaluation

Frank G. Shellock1 , James L. Fleckenstein2
  • 1University of Southern California and Shellock R & D Services, Inc., Los Angeles, California
  • 2University of Texas Southwestern Medical Center, Dallas, Texas
Further Information

Publication History

Publication Date:
31 December 2000 (online)

ABSTRACT

Just as the overlying skin hides skeletal muscle from direct assessment in clinical evaluation of muscle disease, so does it hamper studies that probe basic mechanisms underlying muscle use in exercise science. As a test of organ function, magnetic resonance imaging (MRI) of muscle activation expanded the breadth and type of information available to scientists by allowing the noninvasive dissection of muscle activity, merging functional and morphologic information that link directly to classical tests of muscle performance. Extending to sequellae of overexertion, from the self-limited condition of sore muscles that all of us experience to the more burdensome problems of acute muscle injuries and complications, MRI continues to develop as an important tool to unveil hidden mysteries that underlie and limit locomotion. This article reviews a substantial body of data accumulated over the last 10 years in these interesting, albeit slightly unconventional, applications.

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