Planta Med 2000; 66(2): 176-177
DOI: 10.1055/s-2000-11129
Letter
Georg Thieme Verlag Stuttgart · New York

Biologically Active Triterpenoids of Syncarpia glomulifera Bark Extract from Paluma, North Queensland, Australia

William  N. Setzer1,*, Mary  C. Setzer2 , Robert  B. Bates3 , Betsy  R. Jackes4
  • 1 Department of Chemistry, The University of Alabama in Huntsville, Huntsville, Alabama, U.S.A.
  • 2 Department of Biological Sciences, The University of Alabama in Huntsville, Huntsville, Alabama, U.S.A.
  • 3 Department of Chemistry, The University of Arizona, Tucson, Arizona, U.S.A.
  • 4 Department of Tropical Plant Sciences, James Cook University, Townsville, Queensland, Australia
Further Information

Publication History

Publication Date:
31 December 2000 (online)

Abstract

The crude chloroform bark extract of Syncarpia glomulifera (Myrtaceae) shows antibacterial and cytotoxic activity. Bioactivity-directed separation led to the isolation of oleanolic acid-3-acetate, ursolic acid-3-acetate and betulinic acid. The relatively large abundance (10 % of the crude extract) and high degree of activity of betulinic acid are responsible for the bioactivity of the crude bark extract.

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Professor William N. Setzer

Department of Chemistry

The University of Alabama in Huntsville

Huntsville

AL 35899

USA

Email: wsetzer@matsci.uah.edu

Phone: +1-256-890-6349