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DOI: 10.1055/s-0045-1810630
The Signal-Compromised Lunate
Authors
Abstract
A wide spectrum of conditions can trigger signal alterations in the lunate bone. From vascular complications such as Kienböck's disease to axial microtrauma in ulnocarpal impaction syndrome, the lunate signal is an essential indicator of carpal health. Many of the pathologies described in this review rely on magnetic resonance imaging for analysis; however combined assessment of patient history, clinical symptoms, and imaging is often the only way to find the correct diagnosis. Standard radiography serves as the first-line modality for diagnostic assessment in most patients, but morphological analyses are more precise when based on high-resolution computed tomography imaging. Because gadolinium enhancement (not edema) is the deciding factor in the vitality assessment of the lunate, the imaging work-up of suspected osteonecrosis should include intravenous administration of contrast agent to discern viable tissue and so-called repair zones from entirely necrotic bone.
Declaration of Generative AI and AI-assisted Technologies in the Writing Process
During the preparation of this work, we used ChatGPT 4o to improve readability of the article. After using this tool, we reviewed and edited the content as needed, and we take full responsibility for the content of the article.
Financial Disclosure
Jan-Peter Grunz receives grants from Siemens Healthineers and also payment from the company.
Publication History
Article published online:
03 December 2025
© 2025. Thieme. All rights reserved.
Thieme Medical Publishers, Inc.
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References
- 1 Teisen H, Hjarbaek J. Classification of fresh fractures of the lunate. J Hand Surg [Br] 1988; 13 (04) 458-462
- 2 Schmitt R, Christopoulos G, Kalb K. et al. Differential diagnosis of the signal-compromised lunate in MRI. [in German]. Rofo 2005; 177 (03) 358-366
- 3 Dubey PP, Chauhan NK, Siddiqui MS, Verma AK. Study of vascular supply of lunate and consideration applied to Kienböck disease. Hand Surg 2011; 16 (01) 9-13
- 4 Gelberman RH, Panagis JS, Taleisnik J, Baumgaertner M. The arterial anatomy of the human carpus. Part I: The extraosseous vascularity. J Hand Surg Am 1983; 8 (04) 367-375
- 5 Lamas C, Carrera A, Proubasta I, Llusà M, Majó J, Mir X. The anatomy and vascularity of the lunate: considerations applied to Kienböck's disease. Chir Main 2007; 26 (01) 13-20
- 6 Lichtman DM, Pientka II WF. Kienböck disease: recent advances in understanding and management. J Bone Joint Surg Am 2025; 107 (12) 1389-1402
- 7 Hesse N, Kalb KH, Stohldreier Y, Gildein H, van Schoonhoven J, Schmitt R. Radiography versus computed tomography for osseous staging of Kienböck's disease. J Hand Surg Eur Vol 2025; 50 (05) 643-648
- 8 Schmitt R, Kalb KH, Christopoulos G, Grunz JP. Osteonecrosis of the upper extremity: MRI-based zonal patterns and differential diagnosis. Semin Musculoskelet Radiol 2019; 23 (05) 523-533
- 9 Lichtman DM, Pientka II WF, Bain GI. Kienböck disease: a new algorithm for the 21st century. J Wrist Surg 2017; 6 (01) 2-10
- 10 Arnaiz J, Piedra T, Cerezal L. et al. Imaging of Kienböck disease. AJR Am J Roentgenol 2014; 203 (01) 131-139
- 11 Luitjens J, Goller SS, Schmitt R, Erber B, Van Schoonhoven J, Hesse N. Diagnostic performance of traditional radiographic indices in detection of carpal collapse in Kienböck's disease. J Hand Surg Eur Vol 2023; 48 (07) 619-624
- 12 Tee R, Butler S, Ek ET, Tham SK. Simplifying the decision-making process in the treatment of Kienböck's disease. J Wrist Surg 2024; 13 (04) 294-301
- 13 Lichtman DM, Lesley NE, Simmons SP. The classification and treatment of Kienbock's disease: the state of the art and a look at the future. J Hand Surg Eur Vol 2010; 35 (07) 549-554
- 14 Güvenç K, Asfuroğlu ZM, Yılmaz C, Eskandari MM. Effect of gadolinium perfusion magnetic resonance imaging on surgeons' management preferences in Kienböck's disease. A survey study. Hand Surg Rehabil 2021; 40 (03) 283-287
- 15 Bain GI, Durrant A. An articular-based approach to Kienbock avascular necrosis of the lunate. Tech Hand Up Extrem Surg 2011; 15 (01) 41-47
- 16 Tsantes AG, Papadopoulos DV, Gelalis ID, Vekris MD, Pakos EE, Korompilias AV. The efficacy of vascularized bone grafts in the treatment of scaphoid nonunions and Kienbock disease: a systematic review in 917 patients. J Hand Microsurg 2019; 11 (01) 6-13
- 17 Im JH, Lee JW, Lee JY. Ulnar impaction syndrome and TFCC injury: their relationship and management. J Wrist Surg 2023; 14 (01) 14-26
- 18 Palmer AK, Glisson RR, Werner FW. Relationship between ulnar variance and triangular fibrocartilage complex thickness. J Hand Surg Am 1984; 9 (05) 681-682
- 19 Xu W, Ho PC, Nakamura T. et al. Guidelines for the diagnosis and treatment of ulnar impaction syndrome (2024). J Wrist Surg 2024; 14 (01) 2-13
- 20 Cerezal L, del Piñal F, Abascal F, García-Valtuille R, Pereda T, Canga A. Imaging findings in ulnar-sided wrist impaction syndromes. Radiographics 2002; 22 (01) 105-121
- 21 Leibig N, Lampert FM, Haerle M. Ulnocarpal impaction. Hand Clin 2021; 37 (04) 553-562
- 22 Tomaino MM. Ulnar impaction syndrome in the ulnar negative and neutral wrist. Diagnosis and pathoanatomy. J Hand Surg [Br] 1998; 23 (06) 754-757
- 23 Thillemann JK, De Raedt S, Petersen ET, Puhakka KB, Hansen TB, Stilling M. Normal values of distal radioulnar joint kinematics during a dynamic press test. J Wrist Surg 2021; 11 (05) 406-415
- 24 Mesas Aranda I, Haas-Lützenberger EM, Imam S, Giunta RE, Volkmer E. Algorithm-guided treatment of ulna impaction syndrome: a 10-year follow-up study of ulna shortening osteotomy and wafer procedure. J Clin Med 2024; 13 (13) 3972
- 25 Shi H, Huang Y, Shen Y, Wu K, Zhang Z, Li Q. Arthroscopic wafer procedure versus ulnar shortening osteotomy for ulnar impaction syndrome: a systematic review and meta-analysis. J Orthop Surg Res 2024; 19 (01) 149
- 26 Li S, Sun C, Zhou X, Shi J, Han T, Yan H. Treatment of intraosseous ganglion cyst of the lunate: a systematic review. Ann Plast Surg 2019; 82 (05) 577-581
- 27 Vanhoenacker FM, Eyselbergs M, Van Hul E, Van Dyck P, De Schepper AM. Pseudotumoural soft tissue lesions of the hand and wrist: a pictorial review. Insights Imaging 2011; 2 (03) 319-333
- 28 Prénaud C, Querel D, Mathoulin C, Merlini L. Arthroscopic bone graft for intraosseous lunate bone ganglion. Arthrosc Tech 2021; 10 (12) e2645-e2649
- 29 Bergh TH, Lindau T, Bernardshaw SV. et al. A new definition of wrist sprain necessary after findings in a prospective MRI study. Injury 2012; 43 (10) 1732-1742
- 30 Cievet M, Buffard M, Kumble A, Ramos-Pascual S, Locquet V, Burnier M. ICMMS Group. Outcomes of arthroscopic versus open reduction and internal fixation for the treatment of acute traumatic lunate fractures: a systematic review. Hand Surg Rehabil 2023; 42 (04) 284-290
- 31 Fotiadou A, Patel A, Morgan T, Karantanas AH. Wrist injuries in young adults: the diagnostic impact of CT and MRI. Eur J Radiol 2011; 77 (02) 235-239
- 32 Lee CH, Lee BG, Kim JH, Yoon HS, Han KJ, Choi WS. Complications and outcomes of operative treatment for acute perilunate injuries: a systematic review. J Hand Surg Eur Vol 2023; 48 (07) 625-629
- 33 Goller SS, Hesse N, Dürr HR, Ricke J, Schmitt R. Hydroxyapatite deposition disease of the wrist with intraosseous migration to the lunate bone. Skeletal Radiol 2021; 50 (09) 1909-1913
- 34 Boeren AMP, Ton DA, van Mulligen E. et al. A simplified fluid-sensitive MRI protocol for the hands to detect inflammation without contrast administration: a large study of symptom-free subjects from the general population as a reference for normality. Skeletal Radiol 2025; 54 (07) 1429-1439
- 35 Yang BY, Sartoris DJ, Djukic S, Resnick D, Clopton P. Distribution of calcification in the triangular fibrocartilage region in 181 patients with calcium pyrophosphate dihydrate crystal deposition disease. Radiology 1995; 196 (02) 547-550
- 36 Hoy JF, Ahmad F, Cohen MS, Wysocki RW, Fernandez JJ, Simcock XC. Progression of arthritis after four-corner fusion in patients with calcium pyrophosphate deposition disease: a case series of eleven patients. Explor Musculoskeletal Dis 2024; 2 (04) 256-263
- 37 Mertens K, Mespreuve M, Vanhoenacker FM. Lunotriquetral coalition. Semin Musculoskelet Radiol 2023; 27 (03) 378-380
- 38 Chiri W, Bain GI. Arthroscopic resection of lunotriquetral coalition. Arthrosc Tech 2022; 11 (04) e491-e495
- 39 Schmitt R, Kalb K. Imaging in Kienböck's disease. Handchir Mikrochir Plast Chir 2010; 42 (03) 162-170
