Subscribe to RSS
DOI: 10.1055/s-0043-1774911
Stereoselective Synthesis of Azobenzene-Based Glycomacrocycles


Abstract
Carbohydrate-based macrocyclic compounds are of particular interest because of their multifunctionality, their unique structural and physicochemical properties as well as their potential applications in chemistry, biology, and drug discovery. Introducing a molecular photoswitch into the skeleton of glycomacrocycles makes possible the reversible control of properties of the resulting photoswitchable glycomacrocycles by light illumination. Therefore, development of stereoselective synthesis of this class of glycomacrocycles is of great interest. Two new azobenzene-based glycomacrocycles have been synthesized through an intramolecular glycosylation approach. Excellent 1,2-cis stereoselectivity has been achieved for the mannosylation.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0043-1774911.
- Supporting Information
Publication History
Received: 16 April 2024
Accepted after revision: 24 May 2024
Article published online:
11 June 2024
© 2024. Thieme. All rights reserved
Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany