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DOI: 10.1055/s-0041-1733968
Effects of Stimulus Polarity on Amplitude-Modulated Cervical Vestibular-Evoked Myogenic Potentials
Funding This work was supported by the American Hearing Research Foundation (Christopher G. Clinard and Erin G. Piker); the funding agency had no involvement in the study design, data collection, analysis or interpretation of data, writing, or decision to submit this manuscript for publication.![](https://www.thieme-connect.de/media/10.1055-s-00046128/202109/lookinside/thumbnails/10-1055-s-0041-1733968_21029-1.jpg)
Abstract
Background Traditional approaches to cervical vestibular-evoked myogenic potentials use a transient stimulus to elicit an onset response. However, alternate approaches with long duration stimuli may allow the development of new methodologies to better understand basic function of the vestibular system, as well as potentially developing new clinical applications.
Purpose The objective of this study was to examine the effects of stimulus polarity on response properties of amplitude-modulated cervical vestibular-evoked myogenic potentials (AMcVEMPs).
Research Design Prospective, repeated-measures, within-subjects design.
Study Sample Participants were 16 young, healthy adults (ages 21–38 years).
Data Collection and Analysis Amplitude-modulated tones, with carrier frequency of 500 Hz and modulation frequency of 37 Hz, were used to elicit AMcVEMPs. Responses were analyzed in three different stimulus polarity conditions: condensation, rarefaction, and alternating. The resulting data were analyzed for differences across polarity conditions.
Results AMcVEMP amplitudes, both raw and corrected for tonic muscle activation, were equivalent across the different stimulus phase conditions. In addition, response signal-to-noise ratio and phase coherence were equivalent across the different phases of the stimulus.
Conclusion Analyses of AMcVEMPs are stable when the carrier frequency starting phase is altered and the phase of the temporal envelope is constant.
Authors' Contribution
Christopher G. Clinard and Erin G. Piker designed the research and wrote the article. All authors performed the research and analyzed the data.
Disclaimer
Any mention of a product, service, or procedure in the Journal of the American Academy of Audiology does not constitute an endorsement of the product, service, or procedure by the American Academy of Audiology.
Publication History
Received: 28 February 2021
Accepted: 12 June 2021
Article published online:
17 February 2022
© 2022. American Academy of Audiology. This article is published by Thieme.
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References
- 1 Colebatch JG, Halmagyi GM. Vestibular evoked potentials in human neck muscles before and after unilateral vestibular deafferentation. Neurology 1992; 42 (08) 1635-1636
- 2 Colebatch JG, Halmagyi GM, Skuse NF. Myogenic potentials generated by a click-evoked vestibulocollic reflex. J Neurol Neurosurg Psychiatry 1994; 57 (02) 190-197
- 3 Rosengren SM, Colebatch JG, Young AS, Govender S, Welgampola MS. Vestibular evoked myogenic potentials in practice: methods, pitfalls and clinical applications. Clin Neurophysiol Pract 2019; 4: 47-68
- 4 Clinard CG, Thorne AP, Piker EG. Effects of tonic muscle activation on amplitude-modulated cervical vestibular evoked myogenic potentials (AMcVEMPs) in young females: preliminary findings. J Assoc Res Otolaryngol 2020; 21 (05) 445-461
- 5 Akin FW, Murnane OD, Panus PC, Caruthers SK, Wilkinson AE, Proffitt TM. The influence of voluntary tonic EMG level on the vestibular-evoked myogenic potential. J Rehabil Res Dev 2004; 41 (3B): 473-480
- 6 Bell SL, Fox L, Id Bihi R. Vestibular evoked myogenic responses to amplitude modulated sounds. J Acoust Soc Am 2010; 128 (02) 559-562
- 7 de Oliveira AC, Pereira LD, Colafêmina JF, de Lemos Menezes P. Amplitude modulated vestibular evoked myogenic responses: a study of carrier and modulating frequencies. Acta Otolaryngol 2014; 134 (08) 796-801
- 8 Cai KY, Rosengren SM, Colebatch JG. Cervical and ocular vestibular evoked myogenic potentials are sensitive to stimulus phase. Audiol Neurotol 2011; 16 (05) 277-288
- 9 Govender S, Rosengren SM, Dennis DL, Lim LJ, Colebatch JG. Contrasting phase effects on vestibular evoked myogenic potentials (VEMPs) produced by air- and bone-conducted stimuli. Exp Brain Res 2016; 234 (01) 141-149
- 10 Curthoys IS. A critical review of the neurophysiological evidence underlying clinical vestibular testing using sound, vibration and galvanic stimuli. Clin Neurophysiol 2010; 121 (02) 132-144
- 11 Jurado C, Marquardt T. On the effectiveness of airborne infrasound in eliciting vestibular-evoked myogenic responses. J Low Freq Noise Vib Act Control 2019; 0: 1-14
- 12 Jeng FC, Abbas PJ, Brown CJ, Miller CA, Nourski KV, Robinson BK. Electrically evoked auditory steady-state responses in Guinea pigs. Audiol Neurotol 2007; 12 (02) 101-112
- 13 Picton TW, John MS. Avoiding electromagnetic artifacts when recording auditory steady-state responses. J Am Acad Audiol 2004; 15 (08) 541-554
- 14 Small SA, Stapells DR. Multiple auditory steady-state response thresholds to bone-conduction stimuli in young infants with normal hearing. Ear Hear 2006; 27 (03) 219-228
- 15 Small SA, Stapells DR. Multiple auditory steady-state responses to bone-conduction stimuli in adults with normal hearing. J Am Acad Audiol 2005; 16 (03) 172-183
- 16 John MS, Lins OG, Boucher BL, Picton TW. Multiple auditory steady-state responses (MASTER): stimulus and recording parameters. Audiology 1998; 37 (02) 59-82
- 17 Rosengren SM, McAngus Todd NP, Colebatch JG. Vestibular-evoked extraocular potentials produced by stimulation with bone-conducted sound. Clin Neurophysiol 2005; 116 (08) 1938-1948
- 18 ANSI. American National Standards Institute S3.6 - 2004 Specification for Audiometers;. 2004
- 19 Fisher NI. Statistical analysis of circular data. New York: Cambridge University Press; 1993
- 20 Cohen J. Statistical Power Analysis for the Behavioral Sciences. 2nd ed.. Hillsdale, NJ: Lawrence Erlbaum Associates; 1988
- 21 McCue MP, Guinan Jr JJ. Acoustically responsive fibers in the vestibular nerve of the cat. J Neurosci 1994; 14 (10) 6058-6070
- 22 Young ED, Fernández C, Goldberg JM. Responses of squirrel monkey vestibular neurons to audio-frequency sound and head vibration. Acta Otolaryngol 1977; 84 (5-6): 352-360
- 23 McCue MP, Guinan Jr JJ. Sound-evoked activity in primary afferent neurons of a mammalian vestibular system. Am J Otol 1997; 18 (03) 355-360
- 24 Eatock RA, Songer JE. Vestibular hair cells and afferents: two channels for head motion signals. Annu Rev Neurosci 2011; 34: 501-534
- 25 Holt JR, Eatock RA. Inwardly rectifying currents of saccular hair cells from the leopard frog. J Neurophysiol 1995; 73 (04) 1484-1502
- 26 Soto E, Vega R, Budelli R. The receptor potential in type I and type II vestibular system hair cells: a model analysis. Hear Res 2002; 165 (1-2): 35-47
- 27 Lütkenhöner B. Vestibular evoked myographic correlation. J Assoc Res Otolaryngol 2019; 20 (01) 99-114
- 28 Picton TW, John MS, Dimitrijevic A, Purcell D. Human auditory steady-state responses. Int J Audiol 2003; 42 (04) 177-219
- 29 Small SA, Stapells DR. Artifactual responses when recording auditory steady-state responses. Ear Hear 2004; 25 (06) 611-623
- 30 Thomas MLA, Fitzpatrick D, McCreery R, Janky KL. Big stimulus, little ears: safety in administering vestibular-evoked myogenic potentials in children. J Am Acad Audiol 2017; 28 (05) 395-403
- 31 McNerney KM, Burkard RF. The vestibular evoked myogenic potential (VEMP): air- versus bone-conducted stimuli. Ear Hear 2011; 32 (06) e6-e15
- 32 Basta D, Todt I, Ernst A. Normative data for P1/N1-latencies of vestibular evoked myogenic potentials induced by air- or bone-conducted tone bursts. Clin Neurophysiol 2005; 116 (09) 2216-2219
- 33 Piker EG, Jacobson GP, Burkard RF, McCaslin DL, Hood LJ. Effects of age on the tuning of the cVEMP and oVEMP. Ear Hear 2013; 34 (06) e65-e73
- 34 Kim-Lee Y, Ahn JH, Kim YK, Yoon TH. Tone burst vestibular evoked myogenic potentials: diagnostic criteria in patients with Ménière's disease. Acta Otolaryngol 2009; 129 (09) 924-928
- 35 Clinard CG, Piker EG, Thorne AP. et al. Maximum output and low-frequency limitations of B71 and B81 clinical bone vibrators: implications for vestibular evoked potentials. Ear Hear 2020; 41 (04) 847-854