Planta Med 2019; 85(18): 1484-1485
DOI: 10.1055/s-0039-3399886
Main Congress Poster
Poster Session 1
© Georg Thieme Verlag KG Stuttgart · New York

HPLC-UV/MS phytochemical characterization of the ethanolic tincture of Cardiospermum halicacabum

E Bampali
1   Institute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz,, Universitaetsplatz 4, Graz 8010, Austria
,
EM Pferschy-Wenzig
1   Institute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz,, Universitaetsplatz 4, Graz 8010, Austria
,
R Bauer
1   Institute of Pharmaceutical Sciences, Department of Pharmacognosy, University of Graz,, Universitaetsplatz 4, Graz 8010, Austria
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
20. Dezember 2019 (online)

Auch verfügbar auf
 
 

Cardiospermum halicacabum L. (Sapindaceae), known also as balloon vine, is an important medicinal plant used in homeopathy and in Ayurveda, but also in folk medicine, for the treatment of a variety of diseases, like rheumatism, nervous disorders, chronic bronchitis, and lumbago [1], [2]. Phytochemical studies have shown, that different parts of C. halicacabum contain phenolic acids, flavonols and their glycosides, triterpenoids, a variety of fatty acids and volatile esters, carbohydrates, proteins, saponins, and tannins [3].

Our key aim was to develop a new UPLC-DAD-ESI-MS/MS analytical method as a part of the phytochemical characterization of the ethanolic tincture of the fresh aerial parts of the flowering plant. Although the chemical profiles of extracts from different plant materials are well documented, there is still a lack of knowledge on the chemical constituents.

Chromatograms were compared to standard reference compounds and with literature data of known constituents. The C. halicacabum ethanolic tincture was found to contain the flavones apigenin, luteolin and chrysoeriol, as well as their glucuronides, as already described in the literature [3]. However, the new UPLC method allows also the characterization of nonpolar constituents, such as esters of fatty acids.Consequently, the new method will enable a better quality control based on metabolic profiling.


#

Acknowledgement

We are grateful for the funding of the project by Dr. Willmar Schwabe GmbH & Co. KG.

  • References

  • 1 Subramanyan R, Newmaster GS, Paliyath G, Newmaster BC. Exploring ethnobiological classifications for novel alternative medicine: a case study of Cardiospermum halicacabum L. (Modakathon, Ballon vine) as a traditional herb for treating rheumatoid arthritis. Ethnobotany 2007; 19: 1-16
    PubMedSuche in Google Scholar
  • 2 Dhayabaran D, Florance J, Krsihnadas N, Muralidhar I. Anticonvulsant activity of alcoholic root extract of Cardiospermum halicacabum . Braz J Pharmacogn 2012; 22: 623-629
    PubMedSuche in Google Scholar
  • 3 Cheng HL, Zhang LJ, Liang YH, Hsu YW, Lee IJ, Liaw CC, Hwang SY, Kuo YH. Anti-inflammatory and antioxidant flavonoids and phenols from Cardiospermum halicacabum (倒地鈴 Dào Dì Líng). J Tradit Complement Med 2013; 1: 33-40
    PubMedSuche in Google Scholar

  • References

  • 1 Subramanyan R, Newmaster GS, Paliyath G, Newmaster BC. Exploring ethnobiological classifications for novel alternative medicine: a case study of Cardiospermum halicacabum L. (Modakathon, Ballon vine) as a traditional herb for treating rheumatoid arthritis. Ethnobotany 2007; 19: 1-16
    PubMedSuche in Google Scholar
  • 2 Dhayabaran D, Florance J, Krsihnadas N, Muralidhar I. Anticonvulsant activity of alcoholic root extract of Cardiospermum halicacabum . Braz J Pharmacogn 2012; 22: 623-629
    PubMedSuche in Google Scholar
  • 3 Cheng HL, Zhang LJ, Liang YH, Hsu YW, Lee IJ, Liaw CC, Hwang SY, Kuo YH. Anti-inflammatory and antioxidant flavonoids and phenols from Cardiospermum halicacabum (倒地鈴 Dào Dì Líng). J Tradit Complement Med 2013; 1: 33-40
    PubMedSuche in Google Scholar