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Nervenheilkunde 2008; 27(04): 284-291
DOI: 10.1055/s-0038-1627252
Original- und Übersichtsarbeiten - Original and Review Articles
Schattauer GmbH

Schwache Atmung – schwaches Herz

Atemmuskelversagen und Kardiomyopathie bei neuromuskulären ErkrankungenWeak respiration – weak heartRespiratory muscle failure and cardiomyopathy in neuromuscular disorders
F. Stehling
1   Universtitätsklinikum Essen, Zentrum für Kinderheilkunde, Klinik 2, Abteilung Pädiatrische Pneumologie und Schlafmedizin (Ärztl. Leiter: Priv.-Doz. Dr. med. U. Mellies)
,
C. Müntjes
2   Universtitätsklinikum Essen, Zentrum für Kinderheilkunde, Klinik für Pädiatrische Kardiologie (Direktor: Prof. Dr. med. A. A. Schmaltz)
,
U. Neudorf
2   Universtitätsklinikum Essen, Zentrum für Kinderheilkunde, Klinik für Pädiatrische Kardiologie (Direktor: Prof. Dr. med. A. A. Schmaltz)
,
C. Dohna-Schwake
2   Universtitätsklinikum Essen, Zentrum für Kinderheilkunde, Klinik für Pädiatrische Kardiologie (Direktor: Prof. Dr. med. A. A. Schmaltz)
,
U. Mellies
2   Universtitätsklinikum Essen, Zentrum für Kinderheilkunde, Klinik für Pädiatrische Kardiologie (Direktor: Prof. Dr. med. A. A. Schmaltz)
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Publikationsverlauf

Eingegangen am: 11. Oktober 2007

angenommen am: 18. Oktober 2007

Publikationsdatum:
19. Januar 2018 (online)

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Zusammenfassung

Im letzten Jahrzehnt wurden große Fortschritte in der Diagnostik und Therapie neuromuskulärer Erkrankungen gemacht. Insbesondere die Therapie des chronischen Atemmuskelversagens mit der nicht-invasiven Beatmung konnte Morbidität und Mortalität senken und die Lebensqualität verbessern. Rezidivierende Atemweginfekte und Atelektasen komplizieren den Verlauf bei Patienten mit fortgeschrittenen Erkrankungen und sind Folgen eines insuffizienten Hustens. Ein wichtiger, aber noch nicht ausreichend angewandter Bestandteil der Therapie ist die Technik des assistierten Hustens. Mit steigender Lebenserwartung rückt die Herzbeteiligung als lebenslimitierender Faktor weiter in den Vordergrund. In dieser Übersichtsarbeit wird die aktuelle Datenlage zum Atemmuskelversagen und der Herzbeteiligung bei neuromuskulären Erkrankungen diskutiert.

Summary

Over the last decade crucial progress has been made in diagnosis and therapy of neuromuscular disorders. In particular the therapy of the respiratory muscle failure by noninvasive ventilation lead to a reduction of morbidity and mortality as to an increase of quality of life. In advanced disease recurrent respiratory tract infection and atelecasis are severe complications of an insufficient cough. Assisted coughing techniques are an important, however not routinely established part of respiratory management. With increasing life expectancy the cardiac involvement as life limiting factor comes to the focus. In this review the data to respiratory muscle failure and cardiac involvement in neuromuscular disorders are discussed.

Schlüsselwörter

Respiratorische Insuffizienz - Kardiomyopathie - neuromuskuläre Erkrankung

Keywords

Respiratory failure - cardiomyopathy - neuromuscular disorders
 

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