Thromb Haemost 2001; 85(06): 1118-1119
DOI: 10.1055/s-0037-1615974
Letters to the Editor
Schattauer GmbH

Protein C Concentrates in a Neonate with a Cerebral Venous Thrombosis due to Heterozygous Type 1 Protein C Deficiency

B. Tardy-Poncet
1   Laboratory of Hematology, CHU of St. Etienne, France
,
I. Rayet
2   Pediatric and Neonatal Intensive Care, CHU of St. Etienne, France
,
G. Damon
2   Pediatric and Neonatal Intensive Care, CHU of St. Etienne, France
,
M. Alhenc-Gelas
3   INSERM CJF 91-01, UFR des Sciences Pharmaceutiques et Biologiques, Paris, France
,
N. Dutour
4   Department of Radiology, CHU of St. Etienne, France
,
M. P. Lavocat
2   Pediatric and Neonatal Intensive Care, CHU of St. Etienne, France
› Author Affiliations
Further Information

Publication History

Received 23 August 2000

Accepted after resubmission 30 January 2001

Publication Date:
12 December 2017 (online)

 

 
  • References

  • 1 Nowak-Gottl U, Auberger K, Gobel U. et al. Inherited defects of the protein C anticoagulant system in childhood thrombo-embolism. Eur J Pediatr 1996; 155: 921-7.
  • 2 Gandrille S, Aiach M. Identification of mutations in 90 of 121 consecutive symptomatic french patients with a type I Protein C deficiency. Blood 1995; 86: 2598-605.
  • 3 Andrew M, Brooker LA, Ginsberg JS, Kelton JG. Clinical problems in anticoagulation therapy. Hematology 1997; 8-28.
  • 4 Dreyfus M, Masterson M, David M, Rivard GE, Muller FM, Kreuz W, Beeg T, Minford A, Allgrove J, Cohen JD. Replacement therapy with a monoclonal antibody purified protein C concentrate in newborns with severe congenital protein C deficiency. Semin Thromb Hemost 1995; 21: 371-81.
  • 5 Comp PC, Esmon CT. Generation of fibrinolytic activity by infusion of activated protein C into dogs. J Clin Invest 1981; 68: 1221-8.
  • 6 Monagle P, Andrew M, Halton J, Marlar R, Jardine L, Vegh P, Johnston M, Webber C, Massicotte MP. Homozygous protein C deficiency: description of a new mutation and successful treatment with low molecular weight heparin. Thromb Haemost 1998; 79: 756-61.