Idiopathic Deep Vein Thrombosis in Siblings with Homozygous Factor V Leiden Mutation

• References

• 1 Rosendaal FR, Koster T, Vandenbroucke JP, Reitsma PH. High Risk of Thrombosis in Patients Homozygous for Factor V Leiden (Activated Protein C Resistance). Blood Vol 85 No (Suppl. 06) 1995; pp 1504-1508.
• 2 Svensson PJ, Dahlbäck B. Resistance to activated protein C as a basis for venous thrombosis. N Engl J Med 1994; 330: 517-22.
• 3 Koster T, Rosendaal FR, de Ronde H, Briët E, Vandenbroucke JP, Bertina RM. Venous thrombosis due to poor anticoagulant response to activated protein C: Leiden Thrombophilia Study. Lancet 1993; 342: 1503-6.
• 4 Greengard JS, Eichinger S, Griffin JH, Bauer KA. Variability of Thrombosis among Homozygous Siblings with Resistance to Activated Protein C due to an Arg-Gln Mutation in the Gene for Factor V. N Engl J Med 1994; 331: 1559-62.
• 5 Eichinger S, Pabinger I, Stümpflen A, Hirschl M, Bialonczyk Ch, Schneider B, Mannhalter Ch, Minar E, Lechner K, Kyrle PA. The Risk of Recurrent Venous Thromboembolism in Patients with and without Factor V Leiden. Thromb Haemost 1997; 77 (Suppl. 04) 624-8.