Background: Although it is not so difficult to get access to lesions in the midline via endoscopic
endonasal approach (EEA), it is a bit troublesome to reach lesions in the lateral
skull base due to some complicated anatomy.
Objective: To show surgical anatomy for EEA to the ventrolateral skull base lesions.
Method: Cadaveric heads were dissected using the endoscope. Surgical techniques were applied
to clinical cases.
Results: To get access to the upper lateral skull base (cavernous sinus, orbit), simple opening
of ethmoid sinus via uninostril approach provide sufficient exposure of this area.
To reach the inferior lateral skull base (petrous apex, parapharyngeal space, and
condyle), transpterygoid approach is the key procedure providing wide exposure of
this area. To get to the infratemporal fossa, endoscopic Denker’s approach, followed
by dissection around the lateral pterygoid plate is a feasible technique for accurate
opening of this area.
Conclusion: Understanding of surgical anatomy is mandatory for treating the ventrolateral skull
base lesions via EEA. Less invasive and appropriate approach should be applied depending
on the size, location, and type of the lesion.