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Synfacts 2017; 13(03): 0235
DOI: 10.1055/s-0036-1590063
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag Stuttgart · New York

Synthesis of Idasanutlin (RG7388)

Contributor(s):
Philip Kocienski
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Publication History

Publication Date:
15 February 2017 (online)

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Key words

idasanutlin - MDM2 antagonist - asymmetric [3+2] cycloaddition - azomethine ylides - copper catalysis - silver catalysis