RSS-Feed abonnieren
Bitte kopieren Sie die angezeigte URL und fügen sie dann in Ihren RSS-Reader ein.
https://www.thieme-connect.de/rss/thieme/de/10.1055-s-00000131.xml
Synfacts 2017; 13(01): 0071
DOI: 10.1055/s-0036-1589796
DOI: 10.1055/s-0036-1589796
Metal-Mediated Synthesis
Ring-Forming Thioboration of C–C π-Bonds
Weitere Informationen
Publikationsverlauf
Publikationsdatum:
19. Dezember 2016 (online)
Significance
Blum and co-workers developed a catalyst-free formal thioboration to produce borylated benzothiophenes and dihydrothiophenes in good to high yields.
#
Comment
The authors propose a reaction mechanism in which a boron-induced activation of the alkyne is followed by electrophilic cyclization to generate the borylated benzothiophene after demethylation of the sulfonium intermediate. Boron acts here as a carbophilic Lewis acid.
#
#