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Synthesis 2017; 49(13): 2917-2927
DOI: 10.1055/s-0036-1588792
DOI: 10.1055/s-0036-1588792
special topic
Synthesis of N-Substituted 2-Amino-3,4-diiodofurans from Allenes via NIS-Mediated Intramolecular Electrophilic Iodocyclization
Supported by: National Natural Science Foundation of China (21472136)Supported by: National Basic Research Project (2014CB932201)
Supported by: Tianjin Research Program of Application Foundation and Advanced Technology (15JCZDJC32900)
Further Information
Publication History
Received: 28 February 2017
Accepted after revision: 24 March 2017
Publication Date:
20 April 2017 (online)
![](https://www.thieme-connect.de/media/synthesis/201713/lookinside/thumbnails/ss-2017-c0126-st_10-1055_s-0036-1588792-1.jpg)
Published as part of the Special Topic Modern Strategies with Iodine in Synthesis
Abstract
A facile and efficient method for the syntheses of N-substituted 2-amino-3,4-diiodofurans from various readily available allenic amides has been developed. The reaction was postulated to proceed via an NIS-mediated electrophilic iodocyclization pathway.
Supporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0036-1588792.
- Supporting Information
- CIF File
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For selected examples, see:
For selected examples, see:
For the synthesis of dihalogenated furans, see:
For the synthesis of 2-aminofurans, see: