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Semin Liver Dis 2015; 35(04): 434-438
DOI: 10.1055/s-0035-1567828
DOI: 10.1055/s-0035-1567828
Diagnostic Problems in Hepatology
Beneath the Copper—Pediatric Wilson's Disease Cirrhosis and Hepatocellular Carcinoma: A Case Report with Literature Review
Further Information
Publication History
Publication Date:
16 December 2015 (online)
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Abstract
Primary hepatic malignancies are uncommon in pediatrics. Tumors such as hepatocellular carcinoma (HCC) develop typically in the setting of chronic liver disease. The incidence of HCC in Wilson's disease-related cirrhosis is disproportionately lower than in many other forms of end-stage liver disease. A preadolescent girl presented with Wilson's disease cirrhosis and a HCC requiring orthotopic liver transplantation. This case highlights the need to consider hepatic malignancies even in young Wilson's disease patients. Pediatric Wilson's disease and the hepatic tumor literature are reviewed.
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