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Synthesis 2016; 48(13): 1974-1992
DOI: 10.1055/s-0035-1561974
DOI: 10.1055/s-0035-1561974
short review
Recent Uses of Kröhnke Methodology: A Short Survey
Further Information
Publication History
Received: 07 February 2016
Accepted after revision: 03 March 2016
Publication Date:
09 May 2016 (online)
Abstract
The scope of this short review is to point out how such an old reaction as the Kröhnke-type ring closure is still used nowadays to enable simple access to pyridines or polypyridines. Besides the usual Stille or Suzuki coupling reactions, which deal, respectively, with stannylated derivatives or boronic derivatives, the Kröhnke reaction can reach its target molecules with commercially available starting materials in a simple reaction medium without any special care.
1 Introduction
2 The Kröhnke Reaction
3 Applications
3.1 Catalysis
3.2 Materials
3.2.1 Dye-Sensitized Solar Cells
3.2.2 OLEDs and LECs
3.3 Biological Applications
3.3.1 Luminescent Probes
3.3.2 Chemosensors
3.3.3 Anticancer Compounds
3.3.4 Antimicrobial Activity
4 Miscellaneous
5 Summary and Outlook
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