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Synfacts 2015; 11(12): 1275
DOI: 10.1055/s-0035-1560930
DOI: 10.1055/s-0035-1560930
Metal-Catalyzed Asymmetric Synthesis and Stereoselective Reactions
Ruthenium-Catalyzed Asymmetric Yne–Enone Cyclizations
Further Information
Publication History
Publication Date:
17 November 2015 (online)
Significance
The authors report asymmetric yne–enone cyclizations catalyzed by chiral cationic CpXRuII complexes. A variety of 4H-pyrans were obtained in good yields (≤95%) and high enantioselectivities (er ≤ 99:1).
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Comment
A new class of chiral CpXRuII complexes was synthesized that provide opportunities for the development of synthetically valuable enantioselective transformations.
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