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Synthesis 2016; 48(02): 210-212
DOI: 10.1055/s-0035-1560831
DOI: 10.1055/s-0035-1560831
psp
Easy Synthesis of trans-4,5-Dihydroxy-2-imidazolidinone and 2,4-Dimethylglycoluril
Further Information
Publication History
Received: 31 August 2015
Accepted after revision: 06 October 2015
Publication Date:
03 November 2015 (online)
Abstract
A simple and efficient synthesis of 2,4-dimethylglycoluril involving the formation of trans-4,5-dihydroxy-2-imidazolidinone is presented as well as a reproducible protocol to reduce contamination with its decomposition products, identified as urea and 1,3-dimethylimidazolidine-2,4-dione.
Key words
glyoxal - urea - 1,3-dimethylurea - trans-4,5-dihydroxy-2-imidazolidinone - 2,4-dimethylglycolurilSupporting Information
- Supporting information for this article is available online at http://dx.doi.org/10.1055/s-0035-1560831.
- Supporting Information
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