Download PDF
Clin Colon Rectal Surg 2015; 28(03): 146-151
DOI: 10.1055/s-0035-1555006
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Colorectal Endoscopic Submucosal Dissection: Past, Present, and Factors Impacting Future Dissemination

Jason Ferreira
1   Division of Gastroenterology, Department of Medicine, Rhode Island Hospital, Providence, Rhode Island
,
Paul Akerman
1   Division of Gastroenterology, Department of Medicine, Rhode Island Hospital, Providence, Rhode Island
› Author Affiliations
Further Information

Publication History

Publication Date:
05 October 2015 (online)

Also available at
    Permissions and Reprints

Abstract

First performed in the stomach for removal of localized gastric tumors, endoscopic submucosal dissection (ESD) has evolved into a technique that is increasingly being employed to resect colorectal lesions. As opposed to endoscopic mucosal resection (EMR), ESD allows the endoscopist to remove large specimens en bloc to provide accurate pathologic evaluation and lower local recurrence rates. ESD is an ideal technique for resection of lesions without lymph node metastases and is becoming the standard of care in Japan as outcomes data has proven it to be equally efficacious, less invasive, and inexpensive as compared with surgery; however, potential risk for complications is high and the procedure is currently not widely available in the Western world. As more interest, endoscopist training, and data supporting the technique's use mount, ESD will also likely become the standard of care in the Western world for resection of localized colorectal lesions.

Keywords

endoscopic submucosal dissection - colorectal cancer - endoscopic mucosal resection - endoscopic en bloc resection
 

  • References

  • 1 Hosokawa K, Yoshida S. Recent advances in endoscopic mucosal resection for early gastric cancer [in Japanese]. Gan To Kagaku Ryoho 1998; 25 (4) 476-483
    PubMedGoogle Scholar
  • 2 Repici A, Pellicano R, Strangio G, Danese S, Fagoonee S, Malesci A. Endoscopic mucosal resection for early colorectal neoplasia: pathologic basis, procedures, and outcomes. Dis Colon Rectum 2009; 52 (8) 1502-1515
    CrossrefPubMedGoogle Scholar
  • 3 Ishihara R, Iishi H, Uedo N , et al. Comparison of EMR and endoscopic submucosal dissection for en bloc resection of early esophageal cancers in Japan. Gastrointest Endosc 2008; 68 (6) 1066-1072
    CrossrefPubMedGoogle Scholar
  • 4 Alves A, Panis Y, Mantion G, Slim K, Kwiatkowski F, Vicaut E. The AFC score: validation of a 4-item predicting score of postoperative mortality after colorectal resection for cancer or diverticulitis: results of a prospective multicenter study in 1049 patients. Ann Surg 2007; 246 (1) 91-96
    CrossrefPubMedGoogle Scholar
  • 5 Gotoda T, Kondo H, Ono H , et al. A new endoscopic mucosal resection procedure using an insulation-tipped electrosurgical knife for rectal flat lesions: report of two cases. Gastrointest Endosc 1999; 50 (4) 560-563
    CrossrefPubMedGoogle Scholar
  • 6 Yamamoto H, Kawata H, Sunada K , et al. Successful en-bloc resection of large superficial tumors in the stomach and colon using sodium hyaluronate and small-caliber-tip transparent hood. Endoscopy 2003; 35 (8) 690-694
    Article in Thieme ConnectPubMedGoogle Scholar
  • 7 Fujishiro M, Yahagi N, Kakushima N , et al. Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases. Clin Gastroenterol Hepatol 2007; 5 (6) 678-683
    CrossrefPubMedGoogle Scholar
  • 8 Taku K, Sano Y, Fu KI , et al. Iatrogenic perforation associated with therapeutic colonoscopy: a multicenter study in Japan. J Gastroenterol Hepatol 2007; 22 (9) 1409-1414
    CrossrefPubMedGoogle Scholar
  • 9 Tanaka S, Oka S, Kaneko I , et al. Endoscopic submucosal dissection for colorectal neoplasia: possibility of standardization. Gastrointest Endosc 2007; 66 (1) 100-107
    CrossrefPubMedGoogle Scholar
  • 10 Fujishiro M, Yahagi N, Nakamura M , et al. Successful outcomes of a novel endoscopic treatment for GI tumors: endoscopic submucosal dissection with a mixture of high-molecular-weight hyaluronic acid, glycerin, and sugar. Gastrointest Endosc 2006; 63 (2) 243-249
    CrossrefPubMedGoogle Scholar
  • 11 Takeuchi Y, Uedo N, Ishihara R , et al. Efficacy of an endo-knife with a water-jet function (Flushknife) for endoscopic submucosal dissection of superficial colorectal neoplasms. Am J Gastroenterol 2010; 105 (2) 314-322
    CrossrefPubMedGoogle Scholar
  • 12 Lee BI. Indications, knives, and electric current: what's the best?. Clin Endosc 2012; 45 (3) 285-287
    CrossrefPubMedGoogle Scholar
  • 13 Takeuchi Y, Shimokawa T, Ishihara R , et al. An electrosurgical endoknife with a water-jet function (flushknife) proves its merits in colorectal endoscopic submucosal dissection especially for the cases which should be removed en bloc. Gastroenterol Res Pract 2013; 2013 (13) 530123
    PubMedGoogle Scholar
  • 14 Harada A, Gotoda T, Fukuzawa M, Moriyasu F. Clinical impact of endoscopic devices for colorectal endoscopic submucosal dissection. Digestion 2013; 88 (2) 72-78
    CrossrefPubMedGoogle Scholar
  • 15 Saito Y, Uraoka T, Matsuda T , et al. A pilot study to assess the safety and efficacy of carbon dioxide insufflation during colorectal endoscopic submucosal dissection with the patient under conscious sedation. Gastrointest Endosc 2007; 65 (3) 537-542
    CrossrefPubMedGoogle Scholar
  • 16 Yoshida N, Naito Y, Kugai M , et al. Efficient hemostatic method for endoscopic submucosal dissection of colorectal tumors. World J Gastroenterol 2010; 16 (33) 4180-4186
    CrossrefPubMedGoogle Scholar
  • 17 Tsuji Y, Ohata K, Gunji T , et al. Endoscopic tissue shielding method with polyglycolic acid sheets and fibrin glue to cover wounds after colorectal endoscopic submucosal dissection (with video). Gastrointest Endosc 2014; 79 (1) 151-155
    CrossrefPubMedGoogle Scholar
  • 18 Fujihara S, Mori H, Kobara H , et al. The efficacy and safety of prophylactic closure for a large mucosal defect after colorectal endoscopic submucosal dissection. Oncol Rep 2013; 30 (1) 85-90
    CrossrefPubMedGoogle Scholar
  • 19 Saito Y, Uraoka T, Yamaguchi Y , et al. A prospective, multicenter study of 1111 colorectal endoscopic submucosal dissections (with video). Gastrointest Endosc 2010; 72 (6) 1217-1225
    CrossrefPubMedGoogle Scholar
  • 20 Lee EJ, Lee JB, Lee SH , et al. Endoscopic submucosal dissection for colorectal tumors—1,000 colorectal ESD cases: one specialized institute's experiences. Surg Endosc 2013; 27 (1) 31-39
    CrossrefPubMedGoogle Scholar
  • 21 Repici A, Hassan C, De Paula Pessoa D , et al. Efficacy and safety of endoscopic submucosal dissection for colorectal neoplasia: a systematic review. Endoscopy 2012; 44 (2) 137-150
    Article in Thieme ConnectPubMedGoogle Scholar
  • 22 Hotta K, Yamaguchi Y, Saito Y, Takao T, Ono H. Current opinions for endoscopic submucosal dissection for colorectal tumors from our experiences: indications, technical aspects and complications. Dig Endosc 2012; 24 (Suppl. 01) 110-116
    PubMedGoogle Scholar
  • 23 Nawata Y, Homma K, Suzuki Y. Retrospective study of technical aspects and complications of endoscopic submucosal dissection for large superficial colorectal tumors. Dig Endosc 2014; 26 (4) 552-555
    CrossrefPubMedGoogle Scholar
  • 24 Niimi K, Fujishiro M, Kodashima S , et al. Long-term outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms. Endoscopy 2010; 42 (9) 723-729
    Article in Thieme ConnectPubMedGoogle Scholar
  • 25 Yoshida N, Naito Y, Sakai K , et al. Outcome of endoscopic submucosal dissection for colorectal tumors in elderly people. Int J Colorectal Dis 2010; 25 (4) 455-461
    CrossrefPubMedGoogle Scholar
  • 26 Tamai N, Saito Y, Sakamoto T, Nakajima T, Matsuda T, Tajiri H. Safety and efficacy of colorectal endoscopic submucosal dissection in elders: clinical and follow-up outcomes. Int J Colorectal Dis 2012; 27 (11) 1493-1499
    CrossrefPubMedGoogle Scholar
  • 27 Uraoka T, Higashi R, Kato J , et al. Colorectal endoscopic submucosal dissection for elderly patients at least 80 years of age. Surg Endosc 2011; 25 (9) 3000-3007
    CrossrefPubMedGoogle Scholar
  • 28 Yoon JY, Kim JH, Lee JY , et al. Clinical outcomes for patients with perforations during endoscopic submucosal dissection of laterally spreading tumors of the colorectum. Surg Endosc 2013; 27 (2) 487-493
    CrossrefPubMedGoogle Scholar
  • 29 Hotta K, Shinohara T, Oyama T , et al. Criteria for non-surgical treatment of perforation during colorectal endoscopic submucosal dissection. Digestion 2012; 85 (2) 116-120
    CrossrefPubMedGoogle Scholar
  • 30 Ozawa S, Tanaka S, Hayashi N , et al. Risk factors for vertical incomplete resection in endoscopic submucosal dissection as total excisional biopsy for submucosal invasive colorectal carcinoma. Int J Colorectal Dis 2013; 28 (9) 1247-1256
    CrossrefPubMedGoogle Scholar
  • 31 Suzuki S, Chino A, Kishihara T , et al. Risk factors for bleeding after endoscopic submucosal dissection of colorectal neoplasms. World J Gastroenterol 2014; 20 (7) 1839-1845
    CrossrefPubMedGoogle Scholar
  • 32 Inada Y, Yoshida N, Kugai M , et al. Prediction and treatment of difficult cases in colorectal endoscopic submucosal dissection. Gastroenterol Res Pract 2013; 2013 (13) 523084
    PubMedGoogle Scholar
  • 33 Matsumoto A, Tanaka S, Oba S , et al. Outcome of endoscopic submucosal dissection for colorectal tumors accompanied by fibrosis. Scand J Gastroenterol 2010; 45 (11) 1329-1337
    CrossrefPubMedGoogle Scholar
  • 34 Tajika M, Niwa Y, Bhatia V , et al. Comparison of endoscopic submucosal dissection and endoscopic mucosal resection for large colorectal tumors. Eur J Gastroenterol Hepatol 2011; 23 (11) 1042-1049
    PubMedGoogle Scholar
  • 35 Kobayashi N, Yoshitake N, Hirahara Y , et al. Matched case-control study comparing endoscopic submucosal dissection and endoscopic mucosal resection for colorectal tumors. J Gastroenterol Hepatol 2012; 27 (4) 728-733
    CrossrefPubMedGoogle Scholar
  • 36 Cao Y, Liao C, Tan A, Gao Y, Mo Z, Gao F. Meta-analysis of endoscopic submucosal dissection versus endoscopic mucosal resection for tumors of the gastrointestinal tract. Endoscopy 2009; 41 (9) 751-757
    Article in Thieme ConnectPubMedGoogle Scholar
  • 37 Zhong DD, Shao LM, Cai JT. Endoscopic mucosal resection vs endoscopic submucosal dissection for rectal carcinoid tumours: a systematic review and meta-analysis. Colorectal Dis 2013; 15 (3) 283-291
    CrossrefPubMedGoogle Scholar
  • 38 Watanabe T, Itabashi M, Shimada Y , et al. Japanese Society for Cancer of the Colon and Rectum (JSCCR) guidelines 2010 for the treatment of colorectal cancer. Int J Clin Oncol 2012; 17 (1) 1-29
    CrossrefPubMedGoogle Scholar
  • 39 Haggitt RC, Glotzbach RE, Soffer EE, Wruble LD. Prognostic factors in colorectal carcinomas arising in adenomas: implications for lesions removed by endoscopic polypectomy. Gastroenterology 1985; 89 (2) 328-336
    CrossrefPubMedGoogle Scholar
  • 40 Kudo S, Kashida H, Nakajima T, Tamura S, Nakajo K. Endoscopic diagnosis and treatment of early colorectal cancer. World J Surg 1997; 21 (7) 694-701
    CrossrefPubMedGoogle Scholar
  • 41 The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc 2003; 58 (6, Suppl): S3-S43
    CrossrefPubMedGoogle Scholar
  • 42 Hayashi N, Tanaka S, Hewett DG , et al. Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. Gastrointest Endosc 2013; 78 (4) 625-632
    CrossrefPubMedGoogle Scholar
  • 43 Yanai H, Matsumoto Y, Harada T , et al. Endoscopic ultrasonography and endoscopy for staging depth of invasion in early gastric cancer: a pilot study. Gastrointest Endosc 1997; 46 (3) 212-216
    CrossrefPubMedGoogle Scholar
  • 44 Uraoka T, Saito Y, Matsuda T , et al. Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum. Gut 2006; 55 (11) 1592-1597
    CrossrefPubMedGoogle Scholar
  • 45 Saito Y, Sakamoto T, Fukunaga S , et al. Significance of macroscopic classification of laterally spreading tumors in determining endoscopic treatment strategy. Stom Intest 2010; 45 (6) 1001-1010
    PubMedGoogle Scholar
  • 46 Saito Y, Yamada M, So E , et al. Colorectal endoscopic submucosal dissection: technical advantages compared to endoscopic mucosal resection and minimally invasive surgery. Dig Endosc 2014; 26 (Suppl. 01) 52-61
    PubMedGoogle Scholar
  • 47 Uraoka T, Fujii T, Saito Y , et al. Effectiveness of glycerol as a submucosal injection for EMR. Gastrointest Endosc 2005; 61 (6) 736-740
    CrossrefPubMedGoogle Scholar
  • 48 Niimi K, Fujishiro M, Goto O, Kodashima S, Koike K. Safety and efficacy of colorectal endoscopic submucosal dissection by the trainee endoscopists. Dig Endosc 2012; 24 (Suppl. 01) 154-158
    PubMedGoogle Scholar
  • 49 Iacopini F, Bella A, Costamagna G , et al. Stepwise training in rectal and colonic endoscopic submucosal dissection with differentiated learning curves. Gastrointest Endosc 2012; 76 (6) 1188-1196
    CrossrefPubMedGoogle Scholar
  • 50 Sakamoto T, Sato C, Makazu M , et al. Short-term outcomes of colorectal endoscopic submucosal dissection performed by trainees. Digestion 2014; 89 (1) 37-42
    CrossrefPubMedGoogle Scholar
  • 51 Cohen J. A novel opportunity in minimally invasive colorectal cancer therapy: defining a role for endoscopic submucosal dissection in the United States. Diagn Ther Endosc 2013; 2013 (13) 681783
    PubMedGoogle Scholar
  • 52 Kiriyama S, Saito Y, Yamamoto S , et al. Comparison of endoscopic submucosal dissection with laparoscopic-assisted colorectal surgery for early-stage colorectal cancer: a retrospective analysis. Endoscopy 2012; 44 (11) 1024-1030
    Google Scholar