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Planta Med 2015; 81(07): 613-620
DOI: 10.1055/s-0035-1545906
Analytical Studies
Original Papers
Georg Thieme Verlag KG Stuttgart · New York

Determination by GC-IT/MS of Phytosterols in Herbal Medicinal Products for the Treatment of Lower Urinary Tract Symptoms and Food Products Marketed in Europe

Christoph Müller
Department für Pharmazie, Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität, München, Germany
,
Franz Bracher
Department für Pharmazie, Zentrum für Pharmaforschung, Ludwig-Maximilians-Universität, München, Germany
› Author Affiliations
Further Information

Publication History

received 29 December 2014
revised 17 February 2015

accepted 18 February 2015

Publication Date:
23 April 2015 (online)

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Abstract

A method for the determination of phytosterols in herbal medicinal products for the treatment of lower urinary tract symptoms and food products is described here. Using a convenient sample preparation protocol and sensitive gas chromatography ion trap mass spectrometry analysis, ten different sterols, among them five Δ7-phytosterols as typical constituents of pumpkin seed preparations, could be identified and quantified. This protocol was applied to the analysis of 31 marketed products, from which seven were raw materials.

Key words

gas chromatography ion trap mass spectrometry - Δ7-phytosterols - pumpkin seed extracts - saw palmetto extracts - lower urinary tract symptoms (LUTS)

Supporting Information

 

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