Semin Thromb Hemost 2015; 41(01): 099-107
DOI: 10.1055/s-0034-1398385
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Hemostasis and Thrombosis in Major Liver Resection

Andrea J. Cross
1   Department of Surgery, Christchurch Hospital, Christchurch, New Zealand
,
Saxon J. Connor
1   Department of Surgery, Christchurch Hospital, Christchurch, New Zealand
› Author Affiliations
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Publication History

Publication Date:
15 January 2015 (online)

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Abstract

The liver plays an important role in the balance between hemostasis and thrombosis. Hepatic resection, particularly when performed in the presence of underlying parenchymal liver disease, can cause perturbation of this balance. This review summarizes the changes that occur in normal hemostasis and thrombosis before, during, and after nontransplant hepatic resection and, wherever possible, provides strategies for the perioperative management of bleeding and thrombosis.