Primärer Hyperaldosteronismus – wo liegen die Grenzen der Diagnostik und Therapie?

Schlüsselwörter

arterielle Hypertonie - Hyperaldosteronismus - Conn-Syndrom - Aldosteron-Renin-Quotient

Keywords

arterial hypertension - hyperaldosteronism - Conn‘s syndrome - aldosterone-renin ratio

• Literatur

• 1 Betz MJ, Degenhart C, Fischer E et al. Adrenal vein sampling using rapid cortisol assays in primary aldosteronism is useful in centers with low success rates. Eur J Endocrinol 2011; 165: 301-306
• 2 Fischer E, Beuschlein F. Novel genes in primary aldosteronism. Current opinion in endocrinology, diabetes, and obesity 2014; 21: 154-158
• 3 Fischer E, Beuschlein F, Bidlingmaier M et al. Commentary on the Endocrine Society Practice Guidelines: Consequences of adjustment of antihypertensive medication in screening of primary aldosteronism. Rev Endocr Metab Disorders 2011; 12: 43-48
• 4 Fischer E, Beuschlein F, Reincke M. Diagnostik einer endokrinen Hypertonie: Wann screenen, und mit welchem Test?. Dtsch Med Wochenschr 2011; 136: 537-540
• 5 Fischer E, Hanslik G, Pallauf A et al. Prolonged zona glomerulosa insufficiency causing hyperkalemia in primary aldosteronism after adrenalectomy. J Clin Endocrinol Metab 2012; 97: 3965-3973
• 6 Funder JW, Carey RM, Fardella C et al. Case detection, diagnosis, and treatment of patients with primary aldosteronism: an endocrine society clinical practice guideline. J Clin Endocrinol Metab 2008; 93: 3266-3281
• 7 Hannemann A, Bidlingmaier M, Friedrich N et al. Screening for primary aldosteronism in hypertensive subjects: results from two German epidemiological studies. Eur J Endocrinol 2012; 167: 7-15
• 8 Karagiannis A, Tziomalos K, Kakafika A et al. Eplerenone relieves spironolactone-induced painful gynaecomastia in a patient with primary aldosteronism. Nephrol Dialysis Transplant 2007; 22: 293
• 9 Kupers EM, Amar L, Raynaud A et al. A clinical prediction score to diagnose unilateral primary aldosteronism. J Clin Endocrinol Metab 2012; 97: 3530-3537
• 10 Pallauf A, Schirpenbach C, Zwermann O et al. The prevalence of familial hyperaldosteronism in apparently sporadic primary aldosteronism in Germany: a single center experience. Hormone Metab Res 2012; 44: 215-220
• 11 Pilz S, Kienreich K, Gaksch M et al. Aldosterone to active renin ratio as screening test for primary aldosteronism: reproducibility and influence of orthostasis and salt loading. Hormone Metab Res 2014; 46: 427-432
• 12 Riester A, Fischer E, Degenhart C et al. Age below 40 or a recently proposed clinical prediction score cannot bypass adrenal venous sampling in primary aldosteronism. J Clin Endocrinol Metab 2014; 99: E1035-E1039
• 13 Rossi GP, Auchus RJ, Brown M et al. An expert consensus statement on use of adrenal vein sampling for the subtyping of primary aldosteronism. Hypertension 2013; 63: 151-160
• 14 Rossi GP, Ragazzo F, Seccia TM et al. Hyperparathyroidism can be useful in the identification of primary aldosteronism due to aldosterone-producing adenoma. Hypertension 2012; 60: 431-436
• 15 Rossitto G, Regolisti G, Rossi E et al. Elevation of angiotensin-II type-1-receptor autoantibodies titer in primary aldosteronism as a result of aldosterone-producing adenoma. Hypertension 2013; 61: 526-533
• 16 Tauber P, Penton D, Stindl J et al. Pharmacology and pathophysiology of mutated KCNJ5 found in adrenal aldosterone-producing adenomas. Endocrinology 2014; 155: 1353-1362