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DOI: 10.1055/s-0034-1365746
Miniaturisierte endokardiale Schrittmacher – erste Erfahrungen mit Leadless Pacing
Publication History
Publication Date:
28 July 2014 (online)
![](https://www.thieme-connect.de/media/kardiologie-u2d/201402/lookinside/thumbnails/10.1055-s-0034-1365746-1.jpg)
Abstract
Despite undisputable benefits conventional pacemaker therapy is associated with some specific complications due to the subcutaneous pacemaker placement and the transvenous leads. Recently 2 miniaturized leadless pacemakers, Nanostim (St. Jude Medical) and Micra (Medtronic), that can be fully implanted into the right ventricle using steerable delivery systems entered clinical application. These systems may – additionally to the cosmetic aspects – overcome the problems of conventional pacing. Initial clinical data for the Nanostim system indicate appropriate safety profile and performance. However it is still not completely known, which new complications may arise specific to the new technology, implantation and explantation. Large studies are underway to answer these questions.
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Literatur
- 1 Spickler JW, Rasor NS, Kezdi P et al. Totally self-contained intracardiac pacemaker. J Electrocardiol 1970; 3: 325-331
- 2 Lee KL, Lau CP, Tse HF et al. First human demonstration of cardiac stimulation with transcutaneous ultrasound energy delivery: implications for wireless pacing with implantable devices. J Am Coll Cardiol 2007; 50: 877-883
- 3 Wieneke H, Konorza T, Erbel R et al. Leadless Pacing of the Heart Using Induction Technology: A Feasibility Study. Pacing Clin Electrophysiol 2009; 32: 177-183
- 4 Reddy VY, Knops RE, Sperzel J et al. Permanent Leadless Cardiac pacing – Results of the LEADLESS trial. Circulation 2014; 129: 1466-1471
- 5 Sperzel J et al. Feasibility, efficacy and safety of percutaneous retrieval of a leadless cardiac pacemaker in an in vivo bovine model. Europace 2013;
- 6 The LEADLESS Observational Study. Im Internet: http://clinicaltrials.gov/ct2/show/NCT02051972?term=LEADLESS+Observational&rank=1 ; zuletzt aufgerufen: 28.04.2014
- 7 Micra Transcatheter Pacing Study. Im Internet: http://clinicaltrials.gov/ct2/show/NCT02004873?term=Micra&rank=2 (zuletzt aufgerufen: 28.4.2014)
- 8 Neuzil P, Reddy VY, Merkely B et al. Implantable intravascular defibrillator: Defibrillation thresholds of an intravascular cardioverter-defibrillator compared with those of a conventional ICD in humans. Heart Rhythm 2014; 11: 210-215