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Synthesis 2014; 46(03): 336-342
DOI: 10.1055/s-0033-1338566
DOI: 10.1055/s-0033-1338566
paper
Facile Synthesis of 4-Arylidene-1H-imidazol-5(4H)-ones by an Ugi–Aza-Wittig Sequence
Further Information
Publication History
Received: 05 October 2013
Accepted after revision: 04 November 2013
Publication Date:
22 November 2013 (online)
Abstract
Vinyl azides, obtained from the Ugi-type reaction of 2-azido-3-arylacrylic acid, secondary amine, aldehyde, and isocyanide, react with triphenylphosphine to give a variety of 4-arylidene-1H-imidazol-5(4H)-ones in high yields via sequential Staudinger and intramolecular aza-Wittig reaction.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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