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Synthesis 2013; 45(14): 2003-2008
DOI: 10.1055/s-0033-1338483
DOI: 10.1055/s-0033-1338483
paper
Solvent-Free Iridium(III)-Catalyzed [2+2+2] Cycloaddition Providing Access to Fused Arenes: Isoindolines, Dihydroisobenzofurans and Indanes
Further Information
Publication History
Received: 15 March 2013
Accepted after revision: 29 April 2013
Publication Date:
06 June 2013 (online)
Abstract
A practical and convenient solvent-free iridium-catalyzed [2+2+2] cycloaddition of α,ω-diynes and alkynes to prepare fused arenes has been developed. The method has shown high efficiency as isoindolines, dihydroisobenzofurans and indanes have been synthesized in good to excellent yields.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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For selected reviews on reactions under environmentally friendly and solvent-free conditions, see:
For the enantioselective iridium-catalyzed preparation of polyaromatics, see: