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DOI: 10.1055/s-0032-1325164
Update on Eosinophilic Lung Diseases
Publication History
Publication Date:
21 September 2012 (online)
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Abstract
The eosinophilic lung diseases are a group of pulmonary disorders characterized by an increase in blood and/or lung eosinophils. These disorders can be primary pulmonary disorders or the secondary manifestation of other systemic or pulmonary conditions, infection, drug reaction, or malignancy. The approach to a patient with eosinophilic lung disease involves a thorough history and physical examination, review of exposures and appropriate testing, often including bronchoscopy or lung biopsy, to establish a specific etiology and determine therapy. Eosinophilic lung disease can be suspected based on either the finding of pulmonary disease with blood eosinophilia, pulmonary disease with bronchoalveolar lavage eosinophilia, or pulmonary disease with lung tissue eosinophilia on lung biopsy.
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References
- 1 Wenzel SE, Schwartz LB, Langmack EL , et al. Evidence that severe asthma can be divided pathologically into two inflammatory subtypes with distinct physiologic and clinical characteristics. Am J Respir Crit Care Med 1999; 160 (3) 1001-1008
- 2 Brightling CE, Ward R, Goh KL, Wardlaw AJ, Pavord ID. Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med 1999; 160 (2) 406-410
- 3 Allen JN, Davis WB. Eosinophilic lung diseases. Am J Respir Crit Care Med 1994; 150 (5 Pt 1) 1423-1438
- 4 Blanchard C, Rothenberg ME. Biology of the eosinophil. Adv Immunol 2009; 101: 81-121
- 5 Ponath PD, Qin S, Post TW , et al. Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils. J Exp Med 1996; 183 (6) 2437-2448
- 6 Gotlib J. World Health Organization-defined eosinophilic disorders: 2011 update on diagnosis, risk stratification, and management. Am J Hematol 2011; 86 (8) 677-688
- 7 Simon D, Simon HU. Eosinophilic disorders. J Allergy Clin Immunol 2007; 119 (6) 1291-1300 , quiz 1301–1302
- 8 Allen JN, Davis WB, Pacht ER. Diagnostic significance of increased bronchoalveolar lavage fluid eosinophils. Am Rev Respir Dis 1990; 142 (3) 642-647
- 9 Allen JNDW. Eosinophils. Philadelphia, PA: Lippincott-Raven; 1997
- 10 Löffler W. Zur differential-diagnose der lungeninfiltrierungen, II: Über flüchtige succedan-inflitrate (mit eosinophilie). Beitr Klin Tuberk 1932; 79: 368-392
- 11 Ford RM. Transient pulmonary eosinophilia and asthma. A review of 20 cases occurring in 5,702 asthma sufferers. Am Rev Respir Dis 1966; 93 (5) 797-803
- 12 Christoforidis AJ, Molnar W. Eosinophilic pneumonia. Report of two cases with pulmonary biopsy. JAMA 1960; 173: 157-161
- 13 Carrington CB, Addington WW, Goff AM , et al. Chronic eosinophilic pneumonia. N Engl J Med 1969; 280 (15) 787-798
- 14 Jederlinic PJ, Sicilian L, Gaensler EA. Chronic eosinophilic pneumonia. A report of 19 cases and a review of the literature. Medicine (Baltimore) 1988; 67 (3) 154-162
- 15 Marchand E, Reynaud-Gaubert M, Lauque D, Durieu J, Tonnel AB, Cordier JF. Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies “Orphelines” Pulmonaires (GERM”O”P). Medicine (Baltimore) 1998; 77 (5) 299-312
- 16 Gaensler EA, Carrington CB. Peripheral opacities in chronic eosinophilic pneumonia: the photographic negative of pulmonary edema. AJR Am J Roentgenol 1977; 128 (1) 1-13
- 17 Johkoh T, Müller NL, Akira M , et al. Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients. Radiology 2000; 216 (3) 773-780
- 18 Arakawa H, Kurihara Y, Niimi H, Nakajima Y, Johkoh T, Nakamura H. Bronchiolitis obliterans with organizing pneumonia versus chronic eosinophilic pneumonia: high-resolution CT findings in 81 patients. AJR Am J Roentgenol 2001; 176 (4) 1053-1058
- 19 Samman YS, Wali SO, Abdelaal MA, Gangi MT, Krayem AB. Chronic eosinophilic pneumonia presenting with recurrent massive bilateral pleural effusion: case report. Chest 2001; 119 (3) 968-970
- 20 Liebow AA, Carrington CB. The eosinophilic pneumonias. Medicine (Baltimore) 1969; 48 (4) 251-285
- 21 Kanner RE, Hammar SP. Chronic eosinophilic pneumonia. Ultrastructural evidence of marked immunoglobulin production plus macrophagic ingestion of eosinophils and eosinophilic lysosomes leading to intracytoplasmic Charcot-Leyden crystals. Chest 1977; 71 (1) 95-98
- 22 Shijubo N, Fujishima T, Morita S , et al. Idiopathic chronic eosinophilic pneumonia associated with noncaseating epithelioid granulomas. Eur Respir J 1995; 8 (2) 327-330
- 23 Cooney TP. Interrelationship of chronic eosinophilic pneumonia, bronchiolitis obliterans, and rheumatoid disease: a hypothesis. J Clin Pathol 1981; 34 (2) 129-137
- 24 Olopade CO, Crotty TB, Douglas WW, Colby TV, Sur S. Chronic eosinophilic pneumonia and idiopathic bronchiolitis obliterans organizing pneumonia: comparison of eosinophil number and degranulation by immunofluorescence staining for eosinophil-derived major basic protein. Mayo Clin Proc 1995; 70 (2) 137-142
- 25 Katzenstein AL. Diagnostic features and differential diagnosis of Churg-Strauss syndrome in the lung. A review. Am J Clin Pathol 2000; 114 (5) 767-772
- 26 Lai RS, Lin SL, Lai NS, Lee PC. Churg-Strauss syndrome presenting with pulmonary capillaritis and diffuse alveolar hemorrhage. Scand J Rheumatol 1998; 27 (3) 230-232
- 27 Basset F, Ferrans VJ, Soler P, Takemura T, Fukuda Y, Crystal RG. Intraluminal fibrosis in interstitial lung disorders. Am J Pathol 1986; 122 (3) 443-461
- 28 Phunmanee A, Boonsawat W, Charoensiri DJ, Limkunacul C. Chronic eosinophilic pneumonia: a case report. J Med Assoc Thai 2000; 83 (8) 959-963
- 29 Fox B, Seed WA. Chronic eosinophilic pneumonia. Thorax 1980; 35 (8) 570-580
- 30 Perrault JL, Janis M, Wolinsky H. Resolution of chronic eosinophilic pneumonia with corticoid therapy: demonstration by needle biopsy. Ann Intern Med 1971; 74 (6) 951-954
- 31 Allen JN, Pacht ER, Gadek JE, Davis WB. Acute eosinophilic pneumonia as a reversible cause of noninfectious respiratory failure. N Engl J Med 1989; 321 (9) 569-574
- 32 Badesch DB, King Jr TE, Schwarz MI. Acute eosinophilic pneumonia: a hypersensitivity phenomenon?. Am Rev Respir Dis 1989; 139 (1) 249-252
- 33 Hayakawa H, Sato A, Toyoshima M, Imokawa S, Taniguchi M. A clinical study of idiopathic eosinophilic pneumonia. Chest 1994; 105 (5) 1462-1466
- 34 Pope-Harman AL, Davis WB, Allen ED, Christoforidis AJ, Allen JN. Acute eosinophilic pneumonia. A summary of 15 cases and review of the literature. Medicine (Baltimore) 1996; 75 (6) 334-342
- 35 Shintani H, Fujimura M, Ishiura Y, Noto M. A case of cigarette smoking-induced acute eosinophilic pneumonia showing tolerance. Chest 2000; 117 (1) 277-279
- 36 Uchiyama H, Suda T, Nakamura Y , et al. Alterations in smoking habits are associated with acute eosinophilic pneumonia. Chest 2008; 133 (5) 1174-1180
- 37 Glazer CS, Cohen LB, Schwarz MI. Acute eosinophilic pneumonia in AIDS. Chest 2001; 120 (5) 1732-1735
- 38 Rom WN, Weiden M, Garcia R , et al. Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. Am J Respir Crit Care Med 2002; 166 (6) 797-800
- 39 Shorr AF, Scoville SL, Cersovsky SB , et al. Acute eosinophilic pneumonia among US Military personnel deployed in or near Iraq. JAMA 2004; 292 (24) 2997-3005
- 40 Trawick D, Kotch A, Matthay R, Homer RJ. Eosinophilic pneumonia as a presentation of occult chronic granulomatous disease. Eur Respir J 1997; 10 (9) 2166-2170
- 41 Maeno T, Maeno Y, Sando Y , et al. Nuclear hypersegmentation precedes the increase in blood eosinophils in acute eosinophilic pneumonia. Intern Med 2000; 39 (2) 157-159
- 42 Ogawa H, Fujimura M, Matsuda T, Nakamura H, Kumabashiri I, Kitagawa S. Transient wheeze. Eosinophilic bronchobronchiolitis in acute eosinophilic pneumonia. Chest 1993; 104 (2) 493-496
- 43 King MA, Pope-Harman AL, Allen JN, Christoforidis GA, Christoforidis AJ. Acute eosinophilic pneumonia: radiologic and clinical features. Radiology 1997; 203 (3) 715-719
- 44 Philit F, Etienne-Mastroïanni B, Parrot A, Guérin C, Robert D, Cordier JF. Idiopathic acute eosinophilic pneumonia: a study of 22 patients. Am J Respir Crit Care Med 2002; 166 (9) 1235-1239
- 45 Ricker DH, Taylor SR, Gartner Jr JC, Kurland G. Fatal pulmonary aspergillosis presenting as acute eosinophilic pneumonia in a previously healthy child. Chest 1991; 100 (3) 875-877
- 46 Tazelaar HD, Linz LJ, Colby TV, Myers JL, Limper AH. Acute eosinophilic pneumonia: histopathologic findings in nine patients. Am J Respir Crit Care Med 1997; 155 (1) 296-302
- 47 Churg J, Strauss L. Allergic granulomatosis, allergic angiitis, and periarteritis nodosa. Am J Pathol 1951; 27 (2) 277-301
- 48 Chumbley LC, Harrison Jr EG, DeRemee RA. Allergic granulomatosis and angiitis (Churg-Strauss syndrome). Report and analysis of 30 cases. Mayo Clin Proc 1977; 52 (8) 477-484
- 49 Lanham JG, Elkon KB, Pusey CD, Hughes GR. Systemic vasculitis with asthma and eosinophilia: a clinical approach to the Churg-Strauss syndrome. Medicine (Baltimore) 1984; 63 (2) 65-81
- 50 Guillevin L, Cohen P, Gayraud M, Lhote F, Jarrousse B, Casassus P. Churg-Strauss syndrome. Clinical study and long-term follow-up of 96 patients. Medicine (Baltimore) 1999; 78 (1) 26-37
- 51 Churg A. Recent advances in the diagnosis of Churg-Strauss syndrome. Mod Pathol 2001; 14 (12) 1284-1293
- 52 Keogh KA, Specks U. Churg-Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists. Am J Med 2003; 115 (4) 284-290
- 53 Sablé-Fourtassou R, Cohen P, Mahr A , et al; French Vasculitis Study Group. Antineutrophil cytoplasmic antibodies and the Churg-Strauss syndrome. Ann Intern Med 2005; 143 (9) 632-638
- 54 Mouthon L, Le Toumelin P, Andre MH, Gayraud M, Casassus P, Guillevin L. Polyarteritis nodosa and Churg-Strauss angiitis: characteristics and outcome in 38 patients over 65 years. Medicine (Baltimore) 2002; 81 (1) 27-40
- 55 Neumann T, Manger B, Schmid M , et al. Cardiac involvement in Churg-Strauss syndrome: impact of endomyocarditis. Medicine (Baltimore) 2009; 88 (4) 236-243
- 56 Churg J. Allergic granulomatosis and granulomatous-vascular syndromes. Ann Allergy 1963; 21: 619-628
- 57 Sale S, Patterson R. Recurrent Churg-Strauss vasculitis: with exophthalmos, hearing loss, nasal obstruction, amyloid deposits, hyperimmunoglobulinemia E, and circulating immune complexes. Arch Intern Med 1981; 141 (10) 1363-1365
- 58 Wechsler ME, Garpestad E, Flier SR , et al. Pulmonary infiltrates, eosinophilia, and cardiomyopathy following corticosteroid withdrawal in patients with asthma receiving zafirlukast. JAMA 1998; 279 (6) 455-457
- 59 Hauser T, Mahr A, Metzler C , et al. The leucotriene receptor antagonist montelukast and the risk of Churg-Strauss syndrome: a case-crossover study. Thorax 2008; 63 (8) 677-682
- 60 Wechsler ME, Pauwels R, Drazen JM. Leukotriene modifiers and Churg-Strauss syndrome: adverse effect or response to corticosteroid withdrawal?. Drug Saf 1999; 21 (4) 241-251
- 61 Puéchal X, Rivereau P, Vinchon F. Churg-Strauss syndrome associated with omalizumab. Eur J Intern Med 2008; 19 (5) 364-366
- 62 Wechsler ME, Wong DA, Miller MK, Lawrence-Miyasaki L. Churg-strauss syndrome in patients treated with omalizumab. Chest 2009; 136 (2) 507-518
- 63 Goeken JA. Antineutrophil cytoplasmic antibody—a useful serological marker for vasculitis. J Clin Immunol 1991; 11 (4) 161-174
- 64 Sinico RA, Di Toma L, Maggiore U , et al. Prevalence and clinical significance of antineutrophil cytoplasmic antibodies in Churg-Strauss syndrome. Arthritis Rheum 2005; 52 (9) 2926-2935
- 65 Olivieri D, Pesci A, Bertorelli G. Eosinophilic alveolitis in immunologic interstitial lung disorders. Lung 1990; 168 (Suppl) 964-973
- 66 Cottin V, Khouatra C, Dubost R, Glérant JC, Cordier JF. Persistent airflow obstruction in asthma of patients with Churg-Strauss syndrome and long-term follow-up. Allergy 2009; 64 (4) 589-595
- 67 Szczeklik W, Sokołowska BM, Zuk J, Mastalerz L, Szczeklik A, Musiał J. The course of asthma in Churg-Strauss syndrome. J Asthma 2011; 48 (2) 183-187
- 68 Cooper BJ, Bacal E, Patterson R. Allergic angiitis and granulomatosis: prolonged remission induced by combined prednisone—azathioprine therapy. Arch Intern Med 1978; 138 (3) 367-371
- 69 MacFadyen R, Tron V, Keshmiri M, Road JD. Allergic angiitis of Churg and Strauss syndrome: response to pulse methylprednisolone. Chest 1987; 91 (4) 629-631
- 70 Conron M, Beynon HL. Churg-Strauss syndrome. Thorax 2000; 55 (10) 870-877
- 71 Guillevin L, Lhote F, Gayraud M , et al. Prognostic factors in polyarteritis nodosa and Churg-Strauss syndrome. A prospective study in 342 patients. Medicine (Baltimore) 1996; 75 (1) 17-28
- 72 Guillevin L, Pagnoux C, Seror R, Mahr A, Mouthon L, Le Toumelin P ; French Vasculitis Study Group (FVSG). The Five-Factor Score revisited: assessment of prognoses of systemic necrotizing vasculitides based on the French Vasculitis Study Group (FVSG) cohort. Medicine (Baltimore) 2011; 90 (1) 19-27
- 73 Ribi C, Cohen P, Pagnoux C , et al; French Vasculitis Study Group. Treatment of Churg-Strauss syndrome without poor-prognosis factors: a multicenter, prospective, randomized, open-label study of seventy-two patients. Arthritis Rheum 2008; 58 (2) 586-594
- 74 Cohen P, Pagnoux C, Mahr A , et al; French Vasculitis Study Group. Churg-Strauss syndrome with poor-prognosis factors: A prospective multicenter trial comparing glucocorticoids and six or twelve cyclophosphamide pulses in forty-eight patients. Arthritis Rheum 2007; 57 (4) 686-693
- 75 Guillevin L, Fain O, Lhote F , et al. Lack of superiority of steroids plus plasma exchange to steroids alone in the treatment of polyarteritis nodosa and Churg-Strauss syndrome. A prospective, randomized trial in 78 patients. Arthritis Rheum 1992; 35 (2) 208-215
- 76 Tatsis E, Schnabel A, Gross WL. Interferon-alpha treatment of four patients with the Churg-Strauss syndrome. Ann Intern Med 1998; 129 (5) 370-374
- 77 Jones RB, Tervaert JW, Hauser T , et al; European Vasculitis Study Group. Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis. N Engl J Med 2010; 363 (3) 211-220
- 78 Stone JH, Merkel PA, Spiera R , et al; RAVE-ITN Research Group. Rituximab versus cyclophosphamide for ANCA-associated vasculitis. N Engl J Med 2010; 363 (3) 221-232
- 79 Cartin-Ceba R, Keogh KA, Specks U, Sethi S, Fervenza FC. Rituximab for the treatment of Churg-Strauss syndrome with renal involvement. Nephrol Dial Transplant 2011; 26 (9) 2865-2871
- 80 Dønvik KK, Omdal R. Churg-Strauss syndrome successfully treated with rituximab. Rheumatol Int 2011; 31 (1) 89-91
- 81 Chusid MJ, Dale DC, West BC, Wolff SM. The hypereosinophilic syndrome: analysis of fourteen cases with review of the literature. Medicine (Baltimore) 1975; 54 (1) 1-27
- 82 Fauci AS, Harley JB, Roberts WC, Ferrans VJ, Gralnick HR, Bjornson BH. NIH conference: the idiopathic hypereosinophilic syndrome. Clinical, pathophysiologic, and therapeutic considerations. Ann Intern Med 1982; 97 (1) 78-92
- 83 Klion AD, Bochner BS, Gleich GJ , et al; The Hypereosinophilic Syndromes Working Group. Approaches to the treatment of hypereosinophilic syndromes: a workshop summary report. J Allergy Clin Immunol 2006; 117 (6) 1292-1302
- 84 Ogbogu PU, Bochner BS, Butterfield JH , et al. Hypereosinophilic syndrome: a multicenter, retrospective analysis of clinical characteristics and response to therapy. J Allergy Clin Immunol 2009; 124 (6) 1319-1325 , e3
- 85 Cogan E, Schandené L, Crusiaux A, Cochaux P, Velu T, Goldman M. Brief report: clonal proliferation of type 2 helper T cells in a man with the hypereosinophilic syndrome. N Engl J Med 1994; 330 (8) 535-538
- 86 Raghavachar A, Fleischer S, Frickhofen N, Heimpel H, Fleischer B. T lymphocyte control of human eosinophilic granulopoiesis: clonal analysis in an idiopathic hypereosinophilic syndrome. J Immunol 1987; 139 (11) 3753-3758
- 87 Roufosse F, Schandené L, Sibille C , et al. Clonal Th2 lymphocytes in patients with the idiopathic hypereosinophilic syndrome. Br J Haematol 2000; 109 (3) 540-548
- 88 Simon HU, Plötz SG, Dummer R, Blaser K. Abnormal clones of T cells producing interleukin-5 in idiopathic eosinophilia. N Engl J Med 1999; 341 (15) 1112-1120
- 89 Spry CJ, Davies J, Tai PC, Olsen EG, Oakley CM, Goodwin JF. Clinical features of fifteen patients with the hypereosinophilic syndrome. Q J Med 1983; 52 (205) 1-22
- 90 Parrillo JE, Borer JS, Henry WL, Wolff SM, Fauci AS. The cardiovascular manifestations of the hypereosinophilic syndrome: prospective study of 26 patients, with review of the literature. Am J Med 1979; 67 (4) 572-582
- 91 Dulohery MM, Patel RR, Schneider F, Ryu JH. Lung involvement in hypereosinophilic syndromes. Respir Med 2011; 105 (1) 114-121
- 92 Spry CJ. The hypereosinophilic syndrome: clinical features, laboratory findings and treatment. Allergy 1982; 37 (8) 539-551
- 93 Bain BJ, Fletcher SH. Chronic eosinophilic leukemias and the myeloproliferative variant of the hypereosinophilic syndrome. Immunol Allergy Clin North Am 2007; 27 (3) 377-388
- 94 Klion A. Hypereosinophilic syndrome: current approach to diagnosis and treatment. Annu Rev Med 2009; 60: 293-306
- 95 Slabbynck H, Impens N, Naegels S, Dewaele M, Schandevyl W. Idiopathic hypereosinophilic syndrome-related pulmonary involvement diagnosed by bronchoalveolar lavage. Chest 1992; 101 (4) 1178-1180
- 96 Winn RE, Kollef MH, Meyer JI. Pulmonary involvement in the hypereosinophilic syndrome. Chest 1994; 105 (3) 656-660
- 97 Kang EY, Shim JJ, Kim JS, Kim KI. Pulmonary involvement of idiopathic hypereosinophilic syndrome: CT findings in five patients. J Comput Assist Tomogr 1997; 21 (4) 612-615
- 98 Zielinski RM, Lawrence WD. Interferon-alpha for the hypereosinophilic syndrome. Ann Intern Med 1990; 113 (9) 716-718
- 99 Smit AJ, van Essen LH, de Vries EG. Successful long-term control of idiopathic hypereosinophilic syndrome with etoposide. Cancer 1991; 67 (11) 2826-2827
- 100 Butterfield JH, Gleich GJ. Response of six patients with idiopathic hypereosinophilic syndrome to interferon alfa. J Allergy Clin Immunol 1994; 94 (6 Pt 2) 1318-1326
- 101 Hirashima M, Ueno M, Kamiya K, Higuchi S, Matsumoto R. Functional heterogeneity of human eosinophil chemotactic lymphokines. Lymphokine Cytokine Res 1991; 10 (6) 481-486
- 102 Masunaga T, Tatsumi Y, Miyamori I, Ueno T, Takeda R. A case report of the hypereosinophilic syndrome with eosinophilic peritonitis, revealing abnormal imagings of the liver scintigram and brain computed tomography [in Japanese]. Nippon Naika Gakkai Zasshi 1989; 78 (5) 666-671
- 103 Qazilbash MH, Ueno NT, Hosing C , et al. Strongyloidiasis after unrelated nonmyeloablative allogeneic stem cell transplantation. Bone Marrow Transplant 2006; 38 (5) 393-394
- 104 Sato Y, Matsumoto T, Ueno N, Ohkawa M, Tono-oka T, Takeda T. A case of hypereosinophilic syndrome associated with childhood ALL [in Japanese]. Rinsho Ketsueki 1982; 23 (12) 1895-1901
- 105 Tono-oka T, Sato Y, Matsumoto T , et al. Hypereosinophilic syndrome in acute lymphoblastic leukemia with a chromosome translocation [t(5q;14q)]. Med Pediatr Oncol 1984; 12 (1) 33-37
- 106 Ueno NT, Anagnostopoulos A, Rondón G , et al. Successful non-myeloablative allogeneic transplantation for treatment of idiopathic hypereosinophilic syndrome. Br J Haematol 2002; 119 (1) 131-134
- 107 Ueno NT, Zhao S, Robertson LE, Consoli U, Andreeff M. 2-Chlorodeoxyadenosine therapy for idiopathic hypereosinophilic syndrome. Leukemia 1997; 11 (8) 1386-1390
- 108 Zabel P, Schlaak M. Cyclosporin for hypereosinophilic syndrome. Ann Hematol 1991; 62 (6) 230-231
- 109 Fukushima T, Kuriyama K, Ito H , et al. Successful bone marrow transplantation for idiopathic hypereosinophilic syndrome. Br J Haematol 1995; 90 (1) 213-215
- 110 Sigmund DA, Flessa HC. Hypereosinophilic syndrome: successful allogeneic bone marrow transplantation. Bone Marrow Transplant 1995; 15 (4) 647-648
- 111 Hinson KF, Moon AJ, Plummer NS. Broncho-pulmonary aspergillosis; a review and a report of eight new cases. Thorax 1952; 7 (4) 317-333
- 112 Rosenberg M, Patterson R, Mintzer R, Cooper BJ, Roberts M, Harris KE. Clinical and immunologic criteria for the diagnosis of allergic bronchopulmonary aspergillosis. Ann Intern Med 1977; 86 (4) 405-414
- 113 Vlahakis NE, Aksamit TR. Diagnosis and treatment of allergic bronchopulmonary aspergillosis. Mayo Clin Proc 2001; 76 (9) 930-938
- 114 Patterson R, Greenberger PA, Radin RC, Roberts M. Allergic bronchopulmonary aspergillosis: staging as an aid to management. Ann Intern Med 1982; 96 (3) 286-291
- 115 Patterson R, Greenberger PA, Lee TM , et al. Prolonged evaluation of patients with corticosteroid-dependent asthma stage of allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 1987; 80 (5) 663-668
- 116 Capewell S, Chapman BJ, Alexander F, Greening AP, Crompton GK. Corticosteroid treatment and prognosis in pulmonary eosinophilia. Thorax 1989; 44 (11) 925-929
- 117 Mastella G, Rainisio M, Harms HK , et al. Allergic bronchopulmonary aspergillosis in cystic fibrosis. Eur Respir J 2001; 17 (5) 1052-1053
- 118 Geller DE, Kaplowitz H, Light MJ, Colin AA. Allergic bronchopulmonary aspergillosis in cystic fibrosis: reported prevalence, regional distribution, and patient characteristics. Scientific Advisory Group, Investigators, and Coordinators of the Epidemiologic Study of Cystic Fibrosis. Chest 1999; 116 (3) 639-646
- 119 Egan JJ, Yonan N, Carroll KB, Deiraniya AK, Webb AK, Woodcock AA. Allergic bronchopulmonary aspergillosis in lung allograft recipients. Eur Respir J 1996; 9 (1) 169-171
- 120 Lebecque P, Pepermans X, Marchand E, Leonard A, Leal T. ABPA in adulthood: a CFTR-related disorder. Thorax 2011; 66 (6) 540-541
- 121 Marchand E, Verellen-Dumoulin C, Mairesse M , et al. Frequency of cystic fibrosis transmembrane conductance regulator gene mutations and 5T allele in patients with allergic bronchopulmonary aspergillosis. Chest 2001; 119 (3) 762-767
- 122 Chauhan B, Santiago L, Hutcheson PS , et al. Evidence for the involvement of two different MHC class II regions in susceptibility or protection in allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 2000; 106 (4) 723-729
- 123 Ricketti AJ, Greenberger PA, Patterson R. Serum IgE as an important aid in management of allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 1984; 74 (1) 68-71
- 124 Krasnick J, Greenberger PA, Roberts M, Patterson R. Allergic bronchopulmonary aspergillosis: serologic update for 1995. J Clin Lab Immunol 1995; 46 (3) 137-142
- 125 McCarthy DS, Simon G, Hargreave FE. The radiological appearances in allergic broncho-pulmonary aspergillosis. Clin Radiol 1970; 21 (4) 366-375
- 126 Mitchell TA, Hamilos DL, Lynch DA, Newell JD. Distribution and severity of bronchiectasis in allergic bronchopulmonary aspergillosis (ABPA). J Asthma 2000; 37 (1) 65-72
- 127 Ward S, Heyneman L, Lee MJ, Leung AN, Hansell DM, Müller NL. Accuracy of CT in the diagnosis of allergic bronchopulmonary aspergillosis in asthmatic patients. AJR Am J Roentgenol 1999; 173 (4) 937-942
- 128 Patterson R, Greenberger PA, Halwig JM, Liotta JL, Roberts M. Allergic bronchopulmonary aspergillosis: natural history and classification of early disease by serologic and roentgenographic studies. Arch Intern Med 1986; 146 (5) 916-918
- 129 Franquet T, Müller NL, Giménez A, Guembe P, de La Torre J, Bagué S. Spectrum of pulmonary aspergillosis: histologic, clinical, and radiologic findings. Radiographics 2001; 21 (4) 825-837
- 130 Ward S, Heyneman LE, Flint JD, Leung AN, Kazerooni EA, Müller NL. Bronchocentric granulomatosis: computed tomographic findings in five patients. Clin Radiol 2000; 55 (4) 296-300
- 131 Slavin RG, Bedrossian CW, Hutcheson PS , et al. A pathologic study of allergic bronchopulmonary aspergillosis. J Allergy Clin Immunol 1988; 81 (4) 718-725
- 132 Bosken CH, Myers JL, Greenberger PA, Katzenstein AL. Pathologic features of allergic bronchopulmonary aspergillosis. Am J Surg Pathol 1988; 12 (3) 216-222
- 133 Imbeault B, Cormier Y. Usefulness of inhaled high-dose corticosteroids in allergic bronchopulmonary aspergillosis. Chest 1993; 103 (5) 1614-1617
- 134 Seaton A, Seaton RA, Wightman AJ. Management of allergic bronchopulmonary aspergillosis without maintenance oral corticosteroids: a fifteen-year follow-up. QJM 1994; 87 (9) 529-537
- 135 Salez F, Brichet A, Desurmont S, Grosbois JM, Wallaert B, Tonnel AB. Effects of itraconazole therapy in allergic bronchopulmonary aspergillosis. Chest 1999; 116 (6) 1665-1668
- 136 Stevens DA, Schwartz HJ, Lee JY , et al. A randomized trial of itraconazole in allergic bronchopulmonary aspergillosis. N Engl J Med 2000; 342 (11) 756-762
- 137 Wark PA, Gibson PG, Wilson AJ. Azoles for allergic bronchopulmonary aspergillosis associated with asthma. Cochrane Database Syst Rev 2004; (3) CD001108
- 138 Wark PA, Hensley MJ, Saltos N , et al. Anti-inflammatory effect of itraconazole in stable allergic bronchopulmonary aspergillosis: a randomized controlled trial. J Allergy Clin Immunol 2003; 111 (5) 952-957
- 139 Liebow AA. The J. Burns Amberson lecture—pulmonary angiitis and granulomatosis. Am Rev Respir Dis 1973; 108 (1) 1-18
- 140 Robinson RG, Wehunt WD, Tsou E, Koss MN, Hochholzer L. Bronchocentric granulomatosis: roentgenographic manifestations. Am Rev Respir Dis 1982; 125 (6) 751-756
- 141 Katzenstein AL, Liebow AA, Friedman PJ. Bronchocentric granulomatosis, mucoid impaction, and hypersensitivity reactions to fungi. Am Rev Respir Dis 1975; 111 (4) 497-537
- 142 Wiedemann HP, Bensinger RE, Hudson LD. Bronchocentric granulomatosis with eye involvement. Am Rev Respir Dis 1982; 126 (2) 347-350
- 143 Gelpi AP, Mustafa A. Ascaris pneumonia. Am J Med 1968; 44 (3) 377-389
- 144 Ambrus JL, Klein E. Löffler syndrome and ancylostomiasis brasiliensis. N Y State J Med 1988; 88 (9) 498-499
- 145 Ong RK, Doyle RL. Tropical pulmonary eosinophilia. Chest 1998; 113 (6) 1673-1679
- 146 Cooray JH, Ismail MM. Re-examination of the diagnostic criteria of tropical pulmonary eosinophilia. Respir Med 1999; 93 (9) 655-659
- 147 Lombard CM, Tazelaar HD, Krasne DL. Pulmonary eosinophilia in coccidioidal infections. Chest 1987; 91 (5) 734-736
- 148 Acute Eosinophilic Pneumonia. N Engl J Med 1990; 322 (9) 634-636
- 149 Fleury-Feith J, Van Nhieu JT, Picard C, Escudier E, Bernaudin JF. Bronchoalveolar lavage eosinophilia associated with Pneumocystis carinii pneumonitis in AIDS patients. Comparative study with non-AIDS patients. Chest 1989; 95 (6) 1198-1201
- 150 Kaufman LD, Seidman RJ, Gruber BL. L-tryptophan-associated eosinophilic perimyositis, neuritis, and fasciitis: a clinicopathologic and laboratory study of 25 patients. Medicine (Baltimore) 1990; 69 (4) 187-199
- 151 Philen RM, Hill Jr RH, Flanders WD , et al. Tryptophan contaminants associated with eosinophilia-myalgia syndrome. The Eosinophilia-Myalgia Studies of Oregon, New York and New Mexico. Am J Epidemiol 1993; 138 (3) 154-159
- 152 Kamb ML, Murphy JJ, Jones JL , et al. Eosinophilia-myalgia syndrome in L-tryptophan-exposed patients. JAMA 1992; 267 (1) 77-82
- 153 Swygert LA, Maes EF, Sewell LE, Miller L, Falk H, Kilbourne EM. Eosinophilia-myalgia syndrome. Results of national surveillance. JAMA 1990; 264 (13) 1698-1703
- 154 Alonso-Ruiz A, Calabozo M, Perez-Ruiz F, Mancebo L. Toxic oil syndrome. A long-term follow-up of a cohort of 332 patients. Medicine (Baltimore) 1993; 72 (5) 285-295
- 155 Davis WB, Fells GA, Sun XH, Gadek JE, Venet A, Crystal RG. Eosinophil-mediated injury to lung parenchymal cells and interstitial matrix: a possible role for eosinophils in chronic inflammatory disorders of the lower respiratory tract. J Clin Invest 1984; 74 (1) 269-278
- 156 Watters LC, Schwarz MI, Cherniack RM , et al. Idiopathic pulmonary fibrosis: pretreatment bronchoalveolar lavage cellular constituents and their relationships with lung histopathology and clinical response to therapy. Am Rev Respir Dis 1987; 135 (3) 696-704
- 157 Rudd RM, Haslam PL, Turner-Warwick M. Cryptogenic fibrosing alveolitis. Relationships of pulmonary physiology and bronchoalveolar lavage to response to treatment and prognosis. Am Rev Respir Dis 1981; 124 (1) 1-8
- 158 Hällgren R, Bjermer L, Lundgren R, Venge P. The eosinophil component of the alveolitis in idiopathic pulmonary fibrosis: signs of eosinophil activation in the lung are related to impaired lung function. Am Rev Respir Dis 1989; 139 (2) 373-377
- 159 Peterson MW, Monick M, Hunninghake GW. Prognostic role of eosinophils in pulmonary fibrosis. Chest 1987; 92 (1) 51-56
- 160 Yousem SA. Eosinophilic pneumonia-like areas in idiopathic usual interstitial pneumonia. Mod Pathol 2000; 13 (12) 1280-1284
- 161 Friedman PJ, Liebow AA, Sokoloff J. Eosinophilic granuloma of lung: clinical aspects of primary histiocytosis in the adult. Medicine (Baltimore) 1981; 60 (6) 385-396
- 162 Costabel U, Teschler H, Guzman J. Bronchiolitis obliterans organizing pneumonia (BOOP): the cytological and immunocytological profile of bronchoalveolar lavage. Eur Respir J 1992; 5 (7) 791-797
- 163 Izumi T, Kitaichi M, Nishimura K, Nagai S. Bronchiolitis obliterans organizing pneumonia: clinical features and differential diagnosis. Chest 1992; 102 (3) 715-719
- 164 Bartter T, Irwin RS, Nash G, Balikian JP, Hollingsworth HH. Idiopathic bronchiolitis obliterans organizing pneumonia with peripheral infiltrates on chest roentgenogram. Arch Intern Med 1989; 149 (2) 273-279
- 165 Spry CJF. Eosinophils: A Comprehensive Review, and Guide to the Scientific and Medical Literature. New York, NY: Oxford University Press; 1988
- 166 Kawasaki A, Mizushima Y, Matsui S, Hoshino K, Yano S, Kitagawa M. A case of T-cell lymphoma accompanying marked eosinophilia, chronic eosinophilic pneumonia and eosinophilic pleural effusion. A case report. Tumori 1991; 77 (6) 527-530
- 167 Tan AM, Downie PJ, Ekert H. Hypereosinophilia syndrome with pneumonia in acute lymphoblastic leukaemia. Aust Paediatr J 1987; 23 (6) 359-361
- 168 Bentley HP, Reardon AE, Knoedler JP, Krivit W. Eosinophilic leukemia: Report of a case, with review and classification. Am J Med 1961; 30 (2) 310-322
- 169 Yoshimi M, Nannya Y, Watanabe T , et al. Acute eosinophilic pneumonia is a non-infectious lung complication after allogeneic hematopoietic stem cell transplantation. Int J Hematol 2009; 89 (2) 244-248
- 170 Akhtari M, Langston AA, Waller EK, Gal AA. Eosinophilic pulmonary syndrome as a manifestation of GVHD following hematopoietic stem cell transplantation in three patients. Bone Marrow Transplant 2009; 43 (2) 155-158
- 171 Paralkar VR, Goradia A, Luger SM, Loren AW. Severe eosinophilia as a manifestation of acute graft-versus-host disease. Oncology 2008; 75 (3-4) 134-136