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Synlett 2012; 23(6): 851-854
DOI: 10.1055/s-0031-1290488
DOI: 10.1055/s-0031-1290488
letter
α,β-Unsaturated δ-Valerolactones through RCM–Isomerization Sequence
Further Information
Publication History
Received: 11 January 2012
Accepted after revision: 03 February 2012
Publication Date:
16 March 2012 (online)
![](https://www.thieme-connect.de/media/synlett/201206/lookinside/thumbnails/10.1055-s-0031-1290488-1.jpg)
Abstract
α,β-Unsaturated δ-lactones are accessible via a sequential ring-closing metathesis (RCM) double-bond migration reaction starting from butenoates of allyl alcohols. This approach proceeds efficiently with lower catalyst loadings and higher initial substrate concentrations compared to the alternative RCM of acrylates derived from homoallylic alcohols.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synlett.
- Supporting Information
-
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