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Synthesis 2011(11): 1777-1782  
DOI: 10.1055/s-0030-1260025
PAPER
© Georg Thieme Verlag Stuttgart ˙ New York

A Facile Atom-Economic Synthesis of Imidazoles with Chalcogenophosphoryl Substituents via Free-Radical Addition of Secondary Phosphine Chalcogenides to 1-Vinylimidazoles

Nina K. Gusarova, Svetlana F. Malysheva, Nataliya A. Belogorlova, Lidiya N. Parshina, Boris A. Trofimov*
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences, 1 Favorsky Street, 664033 Irkutsk, Russian Federation
Fax: +7(3952)419346; e-Mail: boris_trofimov@irioch.irk.ru;
Further Information

Publication History

Received 13 February 2011
Publication Date:
05 May 2011 (online)

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Abstract

Secondary phosphine sulfides and selenides react with 1-vinylimidazoles under radical initiation conditions to give the corresponding anti-Markovnikov adducts in up to 98% yields.

Key words

1-vinylimidazoles - phosphine sulfides - phosphine selenides - radical addition

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