Subscribe to RSS
Please copy the URL and add it into your RSS Feed Reader.
https://www.thieme-connect.de/rss/thieme/en/10.1055-s-00000084.xml
Synthesis 2011(1): 123-126
DOI: 10.1055/s-0030-1258341
DOI: 10.1055/s-0030-1258341
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Stereoselective Synthesis of Tetrahydropyranyl Diarylheptanoids (-)-Centrolobine and (+)-Centrolobine
Further Information
Publication History
Received
30 September 2010
Publication Date:
26 November 2010 (online)


Abstract
A versatile chiron approach to the tetrahydropyranyl diarylheptanoid natural products (-)-centrolobine and (+)-centrolobine has been described. The use of an aldol reaction followed by reductive etherification for the formation of tetrahydropyran ring is of importance.
Key words
diarylheptanoid - tetrahydropyran - centrolobine - aldol reaction - reductive etherification