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Dtsch Med Wochenschr 2009; 134: S177-S178
DOI: 10.1055/s-0029-1225320
DOI: 10.1055/s-0029-1225320
Kommentar | Commentary
Pneumologie, Kardiologie
© Georg Thieme Verlag KG Stuttgart · New York
Endothelinrezeptor-Antagonisten in der Therapie der pulmonalen arteriellen Hypertonie
Endothelin-receptor antagonists in therapy of pulmonary arterial hypertensionFurther Information
Publication History
Publication Date:
28 August 2009 (online)
Schlüsselwörter
pulmonale arterielle Hypertonie - Endothelinrezeptor-Antagonisten
Keywords
pulmonary arterial hypertension - endothelin-receptor antagonist
Literatur
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- 2 DiCarlo V S, Chen S J, Meng Q C. et al . ETA-receptor antagonist prevents and reverses chronic hypoxia-induced pulmonary hypertension in rat. Am J Physiol. 1995; 269 (5 Pt1) 1690-1697
- 3 Givertz M M, Colucci W S, LeJemtel T H. et al . Acute endothelin A receptor blockade causes selective pulmonary vasodilation in patients with chronic heart failure. Circulation. 2000; 101 2922-2927
- 4 Hiramoto Y, Shioyama W, Kuroda T. et al . Effect of bosentan on plasma endothelin-1 concentration in patients with pulmonary arterial hypertension. Circ J. 2007; 71 367-369
- 5 Kiowski W, Sütsch G, Hunziker P. et al . Evidence for endothelin-1-mediated vasoconstriction in severe chronic heart failure. Lancet. 1995; 346 732-736
- 6 Rubens C, Ewert R, Halank M. et al . Big endothelin-1 and endothelin-1 plasma levels are correlated with the severity of primary pulmonary hypertension. Chest. 2001; 120 1562-1569
- 7 Sütsch G, Kiowski W, Yan X W. et al . Short-term oral endothelin-receptor antagonist therapy in conventionally treated patients with symptomatic severe chronic heart failure. Circulation. 1998; 98 2262-2268
- 8 Williamson D J, Wallman L L, Jones R. et al . Hemodynamic effects of Bosentan, an endothelin receptor antagonist, in patients with pulmonary hypertension. Circulation. 2000; 102 411-418
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