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Synfacts 2009(6): 0590-0590
DOI: 10.1055/s-0029-1216675
DOI: 10.1055/s-0029-1216675
Synthesis of Natural Products and Potential Drugs
© Georg Thieme Verlag
Stuttgart ˙ New York
Synthesis of (+)-Lepadin F
G. Li, R. P. Hsung*, B. W. Slafer, I. K. Sagamanova
University of Wisconsin, Madison, USA
Further Information
Publication History
Publication Date:
25 May 2009 (online)
![](https://www.thieme-connect.de/media/synfacts/200906/lookinside/thumbnails/10.1055-s-0029-1216675-1.jpg)
Significance
(+)-Lepadin F was isolated from Aplidium tabascum, an Australian ascidian. The lepadin family possesses antiplasmodial and antitrypanosomal properties. For the first enantioselective total synthesis of (+)-lepadin F see: A. Niethe, D. Fischer, S. Blechert J. Org. Chem. 2008, 73, 3088.