Endoscopy 2009; 41: E78-E79
DOI: 10.1055/s-0029-1214429
Unusual cases and technical notes

© Georg Thieme Verlag KG Stuttgart · New York

Wire-guided endoscopic snare resection of a choledochocele-associated villous adenoma

J.  K.  Park1 , J.  H.  Moon1 , H.  K.  Kim1 , H.  J.  Choi1 , J.  H.  Kang1 , H.  K.  Kim2 , B.  M.  Ko1 , Y.  D.  Cho1 , M.  S.  Lee1 , C.  S.  Shim1
  • 1Digestive Disease Center, Department of Internal Medicine, Soon Chun Hyang University School of Medicine, Bucheon and Seoul, Korea
  • 2Department of Pathology, Soon Chun Hyang University School of Medicine, Bucheon, Korea
Further Information

J. H. MoonMD, PhD 

Soon Chun Hyang University School of Medicine
Digestive Disease Center
Soon Chun Hyang University Bucheon Hospital

1174 Jung-Dong
Wonmi-Ku
Bucheon 420-767
Korea

Fax: +82-32-6215080

Email: jhmoon@schbc.ac.kr

Publication History

Publication Date:
15 April 2009 (online)

Table of Contents

Adenomas arising in a choledochocele are usually resected surgically because they are difficult to completely remove endoscopically and they are associated with a high malignancy potential [1] [2]. We successfully performed an endoscopic snare resection for choledochocele-associated villous adenoma with high-grade dysplasia.

A 76-year-old woman was admitted complaining of epigastric pain lasting for several days. Duodenoscopy revealed a soft cystic-mass-like lesion covered with normal mucosa above the ampulla of Vater ([Fig. 1]).

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Fig. 1 Endoscopic view of the choledochocele.

Intraductal ultrasound showed an anechogenic cystic mass with diffuse wall thickening and preserved wall layer ([Fig. 2]).

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Fig. 2 Intraductal ultrasound showing an anechogenic cystic mass with diffuse wall thickening.

Magnetic resonance cholangiopancreatography showed an oval-shaped cystic mass above the ampulla of Vater. A major endoscopic sphincterotomy was conducted. Following sphincterotomy, duodenoscopy revealed mucosal nodules on the inner surface of the choledochocele ([Fig. 3]).

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Fig. 3 Endoscopic view after a major endoscopic sphincterotomy.

Histopathologic findings of the biopsy specimen showed an adenoma with high-grade dysplasia ([Fig. 4]).

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Fig. 4 Histopathologic findings of the biopsy specimen (hematoxylin and eosin stain, × 200).

Because the patient wanted to undergo an endoscopic treatment, we performed a wire-guided endoscopic snare resection for the choledochocele with the adenoma ([Fig. 5], [Video 1] []).

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Fig. 5 Endoscopic view for the wire-guided endoscopic snare resection.


Quality:

Video 1 Wire-guided endoscopic snare resection. The guide wire was inserted into the main pancreatic duct. An electrosurgical snare was then inserted along the guide wire. The snare was manipulated to grasp the base of the choledochocele before en bloc resection was conducted. After the excision had been completed, a pancreatic stent was immediately placed along the indwelling guide wire. Histopathologic examination of the resected specimen showed a villous adenoma with a clear resection margin (Fig. 6).

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Fig. 6 Histopathologic picture of the endoscopic resected specimen showing villous adenoma (hematoxylin and eosin stain, × 10).

During the 1-year follow-up duodenoscopy, no remnant or recurrence of the adenoma was found.

The surgical approach may be too invasive for a choledochocele with adenoma. Itoi et al. [3] performed a balloon-catheter-assisted endoscopic snare resection using a double-channel duodenoscope for choledochocele. We attempted to perform a wire-guided endoscopic snare resection using the previously reported method for adenomas of the major papilla [4]. En bloc resection was successfully achieved without any procedure-related complications or residual tumor. In conclusion, endoscopic snare resection may be a feasible and effective solution for selected patients with choledochocele associated with a villous adenoma.

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References

  • 1 Kawakami H, Kuwatani M, Onodera M. et al . Villous adenoma arising in choledochocele.  Gastrointest Endosc. 2007;  66 1231-1232
  • 2 Ohtsuka T, Inoue K, Ohuchida J. et al . Carcinoma arising in choledochocele.  Endoscopy. 2001;  33 614-619
  • 3 Itoi T, Gotoda T, Yasuda I. et al . Balloon-catheter-assisted complete endoscopic snare resection for choledochocele by using double-channel duodenoscope (with videos).  Gastrointest Endosc. 2007;  66 622-625
  • 4 Moon J H, Cha S W, Cho Y D. et al . Wire-guided endoscopic snare papillectomy for tumors of the major duodenal papilla.  Gastrointest Endosc. 2005;  61 461-466

J. H. MoonMD, PhD 

Soon Chun Hyang University School of Medicine
Digestive Disease Center
Soon Chun Hyang University Bucheon Hospital

1174 Jung-Dong
Wonmi-Ku
Bucheon 420-767
Korea

Fax: +82-32-6215080

Email: jhmoon@schbc.ac.kr

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References

  • 1 Kawakami H, Kuwatani M, Onodera M. et al . Villous adenoma arising in choledochocele.  Gastrointest Endosc. 2007;  66 1231-1232
  • 2 Ohtsuka T, Inoue K, Ohuchida J. et al . Carcinoma arising in choledochocele.  Endoscopy. 2001;  33 614-619
  • 3 Itoi T, Gotoda T, Yasuda I. et al . Balloon-catheter-assisted complete endoscopic snare resection for choledochocele by using double-channel duodenoscope (with videos).  Gastrointest Endosc. 2007;  66 622-625
  • 4 Moon J H, Cha S W, Cho Y D. et al . Wire-guided endoscopic snare papillectomy for tumors of the major duodenal papilla.  Gastrointest Endosc. 2005;  61 461-466

J. H. MoonMD, PhD 

Soon Chun Hyang University School of Medicine
Digestive Disease Center
Soon Chun Hyang University Bucheon Hospital

1174 Jung-Dong
Wonmi-Ku
Bucheon 420-767
Korea

Fax: +82-32-6215080

Email: jhmoon@schbc.ac.kr

Zoom Image

Fig. 1 Endoscopic view of the choledochocele.

Zoom Image

Fig. 2 Intraductal ultrasound showing an anechogenic cystic mass with diffuse wall thickening.

Zoom Image

Fig. 3 Endoscopic view after a major endoscopic sphincterotomy.

Zoom Image

Fig. 4 Histopathologic findings of the biopsy specimen (hematoxylin and eosin stain, × 200).

Zoom Image

Fig. 5 Endoscopic view for the wire-guided endoscopic snare resection.

Zoom Image

Fig. 6 Histopathologic picture of the endoscopic resected specimen showing villous adenoma (hematoxylin and eosin stain, × 10).