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Synthesis
DOI: 10.1055/a-2281-2975
DOI: 10.1055/a-2281-2975
paper
Special Issue PSRC-10 (10th Pacific Symposium on Radical Chemistry)
Use of Aliphatic Carboxylic Acid Derivatives for NHC/Photoredox-Catalyzed meta-Selective Acylation of Electron-Rich Arenes
This work was supported by the Japan Society for the Promotion of Science (JSPS), KAKENHI (Grant Nos. JP21H04681 and JP23H04912) to H.O.
![](https://www.thieme-connect.de/media/synthesis/EFirst/lookinside/thumbnails/ss-2024-f0031-op_10-1055_a-2281-2975-1.jpg)
Abstract
We describe the use of acyl imidazoles derived from aliphatic carboxylic acids for the N-heterocyclic carbene/organic photoredox co-catalyzed meta-selective functionalization of electron-rich arenes. Compared to our previous work, a change of the wavelength of the applied LED light from 440 nm to 390 nm promotes this reaction efficiently.
Supporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/a-2281-2975.
- Supporting Information
Publication History
Received: 28 January 2024
Accepted after revision: 05 March 2024
Accepted Manuscript online:
05 March 2024
Article published online:
25 March 2024
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