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DOI: 10.1055/a-1633-2762
A modified approach for endoscopic ultrasound-guided management of disconnected pancreatic duct syndrome via drainage of a communicating collection
Endoscopic ultrasound (EUS)-guided pancreaticogastrostomy to drain the viable upstream pancreas in patients with disconnected pancreatic duct syndrome is technically challenging [1]. Here, we present a modified EUS-guided pancreaticogastrostomy via drainage of a fluid collection in communication with the duct disruption ([Video 1]).
Video 1 Endoscopic ultrasound-guided management of disconnected pancreatic duct syndrome via drainage of a communicating collection.
Quality:
The first patient is a 63-year-old woman with recurrent acute pancreatitis referred for management of disconnected pancreatic duct syndrome. EUS revealed a 3.9-cm pancreatic body necrotic fluid collection ([Fig. 1]) and a mildly dilated main pancreatic duct in the tail. On contrast injection into the dilated duct, the necrotic collection also filled with contrast, indicating communication with the main pancreatic duct in the tail. However, EUS-guided pancreaticogastrostomy was not feasible owing to acute angulation between the main pancreatic duct and the needle. Given the communication between the duct and the necrotic collection into which the pancreatic juices from the upstream viable pancreas were flowing, a transgastric approach was chosen to drain the collection ([Fig. 2]). Under EUS guidance, a 15 × 10-mm lumen-apposing metal stent (LAMS) was deployed into the collection along with a coaxial 7 Fr 5-cm double-pigtail plastic stent. Repeat imaging 2 months later revealed the resolution of the necrotic collection, so the LAMS was removed and the stent left indefinitely for treatment of disconnected pancreatic duct syndrome.
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The second patient is a 63-year-old man presenting with recurrent acute pancreatitis. Computed tomography (CT) imaging of the abdomen revealed a 3.5-cm mixed fluid collection in the pancreatic neck and a mildly dilated main pancreatic duct at the tail. On secretin-stimulated magnetic resonance cholangiopancreatography (MRCP), the main pancreatic duct was seen traveling into and out of the fluid collection but not within it ([Fig. 3]), suggesting its complete disruption (disconnected pancreatic duct syndrome). Wire placement across the disruption during endoscopic retrograde cholangiopancreatography (ERCP) was unsuccessful ([Fig. 4]). EUS-guided pancreaticogastrostomy was considered and contrast was injected into the dilated duct in the tail. The fluid collection also filled with contrast, indicating communication with the main pancreatic duct. A 0.025-inch guidewire was advanced through the duct in the tail and was allowed to coil within the collection. A 7 Fr 9-cm double-pigtail plastic stent was then deployed into the duct and the collection, creating the pancreaticogastrostomy ([Fig. 5]).
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Neither patient had any recurrence of acute pancreatitis on 6-months follow-up.
In these two cases, the presence of a fluid collection in communication with the disrupted main pancreatic duct rendered a technically challenging EUS-guided pancreaticogastrostomy more feasible and successful using an EUS-guided cystogastrostomy.
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Competing interests
Mouen A Khashab is a consultant for Boston Scientific, Apollo, Olympus America, Medtronic and GI Supply. All other authors have no disclosures.
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Reference
- 1 Nadkarni NA, Kotwal V, Sarr MG. et al. Disconnected pancreatic duct syndrome: endoscopic stent or surgeonʼs knife?. Pancreas 2015; 44: 16-22
Corresponding author
Publication History
Article published online:
01 October 2021
© 2021. Thieme. All rights reserved.
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Reference
- 1 Nadkarni NA, Kotwal V, Sarr MG. et al. Disconnected pancreatic duct syndrome: endoscopic stent or surgeonʼs knife?. Pancreas 2015; 44: 16-22
![](https://www.thieme-connect.de/media/endoscopy/202209/thumbnails/10-1055-a-1633-2762-i2586ev1.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
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![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
![](https://www.thieme-connect.de/media/endoscopy/202209/thumbnails/10-1055-a-1633-2762-i2586ev3.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
![](https://www.thieme-connect.de/media/endoscopy/202209/thumbnails/10-1055-a-1633-2762-i2586ev4.jpg)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)
![](https://www.thieme-connect.de/media/endoscopy/202209/thumbnails/10-1055-a-1633-2762-i2586ev5.gif)
![Zoom Image](/products/assets/desktop/css/img/icon-figure-zoom.png)