Erworbenes transientes Fanconi-Syndrom nach Fütterung von Trockenfleisch als Leckerchen beim Hund

Zusammenfassung

Zwischen April 2018 und August 2019 wurden 6 Hunde mit labordiagnostischen Hinweisen auf ein Fanconi-Syndrom in der Tierklinik Hofheim vorgestellt. In allen Fällen ließ sich der Verdacht mittels Untersuchung der Aminosäuren im Harn bestätigen. Bei 5 der 6 Hunde bestand der hochgradige Verdacht auf eine alimentäre Genese, bei 3 Hunden konnte der Verlauf der Krankheit verfolgt werden. Durch unterstützende therapeutische Maßnahmen und Elimination der Leckerchen aus Trockenfleisch vom Speiseplan besserte sich die klinische Symptomatik bei den Hunden mit Verlaufskontrolle. Hierbei handelt es sich um die erste Fallserie von in Deutschland erkrankten Hunden. Die Häufigkeit des Auftretens des Fanconi-Syndroms in etwas mehr als einem Jahr in nur einer Tierklink lässt eine deutlich höhere Inzidenz vermuten, als derzeit angenommen wird.

Abstract

Between April 2018 and August 2019, 6 dogs with laboratory diagnostic evidence of Fanconi syndrome were presented to the Tierklinik Hofheim. The presumptive diagnosis was confirmed via urine amino acid analysis in all dogs. In 5 of the 6 dogs an alimentary origin was suspected, in 3 dogs the course of the disease could be followed. Supportive therapeutic measures and elimination of jerky treats from the dogs’ diet improved the clinical symptoms in all dogs with known follow-up. This is the first case series of dogs with alimentary acquired Fanconi syndrome in Germany. The frequency of occurrence of the disease in that short period of time in only one small animal clinic suggests a significantly higher incidence than currently assumed.

Schlüsselwörter

Polyurie - Polydipsie - proximale Tubulusschädigung - Glukosurie - Hyperaminoazidurie - COLA

Key words

Polyuria - polydipsia - proximal tubule damage - glucosuria - hyperaminoaciduria - COLA

Publication History

Received: 01 June 2020

Accepted: 01 December 2020

Article published online:
23 August 2021

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