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DOI: 10.1055/a-1197-6380
Mortality of Patients with Cushing’s Disease
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Abstract
Cushing’s disease is a rare condition of cortisol excess attributed to a pituitary adenoma with an annual incidence of 1.2–2.4 cases per million population. It is associated with several co-morbidities leading to increased mortality predominantly due to cardiovascular disease. Despite the advances in its diagnosis and management, survival can be compromised even after apparent successful treatment. Minimizing the duration and extent of exposure to hypercortisolaemia by early diagnosis and rapid, effective therapeutic interventions, as well as close monitoring and aggressive control of cardiovascular risk factors are vital for improving outcomes of the patients.
Key words
Cushing’s disease - cortisol excess - mortality - survival - remission - cardiovascular riskPublication History
Received: 29 April 2020
Received: 02 June 2020
Accepted: 09 June 2020
Article published online:
09 July 2020
© 2020. Thieme. All rights reserved.
Georg Thieme Verlag KG
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