Int Arch Otorhinolaryngol 2012; 16(03): 410-413
DOI: 10.7162/S1809-97772012000300019
Case Report
Thieme Publicações Ltda Rio de Janeiro, Brazil

Extramedullary plasmacytoma of the larynx

José Antônio Pinto
1   President of the Brazilian Society of Laryngology and Voice (2001-2003). Director of the Center for Otolaryngology and Head and Neck Surgery of São Paulo.
,
Thiago Branco Sônego
2   Resident Doctor of the Center for Otolaryngology and Head and Neck Surgery of São Paulo.
,
Marina Spadari Artico
2   Resident Doctor of the Center for Otolaryngology and Head and Neck Surgery of São Paulo.
,
Carolina de Farias Aires Leal
2   Resident Doctor of the Center for Otolaryngology and Head and Neck Surgery of São Paulo.
,
Silvana Bellotto
3   Otolaryngologist.
› Author Affiliations
Further Information

Publication History

08 June 2010

01 August 2010

Publication Date:
05 December 2013 (online)

Summary

Introduction: The extramedullary plasmocytoma is one of the localized forms of malignancy of the plasma cells, which has multiple myeloma main diagnosis. Its main site to the head and neck, but with a rare presentation in the larynx.

Objective: To describe a case of extramedullary plasmocytoma of the larynx, with literature review.

Case Report: Patient female, 49, referring to intermittent dysphonia for 01 years with progressive worsening associated with vocal fatigue and vocal effort, with reddish lesion, smooth edges fold left ventricular endoscopy. Being subjected to excisional biopsy diagnosed with extramedullary histopathological plasmocytoma.

Conclusion: Extramedullary Plasmocytoma must be considered in the differential diagnosis of rare tumors of the larynx. It is essential after the diagnosis of multiple myeloma research and a “follow up” appropriate.

 
  • References

  • 1 Zbären P, Läng H, Beer K, Becker M. Plasma cell granuloma of the supraglottic larynx. J Laryngol Otol 1995; 109 (9) 895-8
  • 2 Susnerwala SS, Shanks JH, Banerjee SS, Scarffe JH, Farrington WT, Slevin NJ. Extramedullary plasmocytoma of the head and neck region: clinicopathological correlation in 25 cases. Br J Cancer 1997; 75 (6) 921-7
  • 3 Bjelkenkratz K, Lundgren J, Olofsson J. Extramedullary plasmocytoma of the larynx. J Otolaryngol 1981; 10 (1) 28-34
  • 4 Pratibha CB, Sreenivas V, Babu MK, Rout P, Nayar RC. Plasmacytoma of Larynx - A Case Report. J. Voice 2009; 23 (6) 735-8
  • 5 Gorenstein A, Bryan Neel H, Devine KD, Weiland LH. Solitary extramedullary plasmocytoma of the larynx. Arch Otolaryngol 1977; 103 (3) 159-61
  • 6 Maniglia AJ, Xue JW. Plasmocytoma of the larynx. Laryngoscope 1983; 93 (6) 741-744
  • 7 Nakashima T, Matsuda K, Haruta A. Extramedullary plasmocytoma of the larynx. Auris Auris Nasus Larynx 2006; 33 (2) 219-22
  • 8 Hotz MA, Bosq J, Schwaab G, Munck J. Extramedullary solitary plasmocytoma of the head and neck. Ann Otol Rhinol Laryngol 1999; 108 (5) 495-500
  • 9 Jyothirmayi R, Gangadharan VP, Nair MK, Rajan B. Radiotherapy in the treatment of solitary plasmocytoma. Br J Radiol 1997; 70 (833): 511-6
  • 10 Velez D, Hinojar-Gutierrez Z, Nam-Cha S , Acevedo-Barbera 2007 A. Laryngeal Plasmacytoma presenting as amyloid tumour: a case report. Eur Arch Otorhinolaryngol 2007; 264 (8) 959-61
  • 11 Creach KM, Foote RL, Neben-Wittich MA, Kyle RA. Radiotherapy for extramedullary plasmocytoma of the head and neck. Int J Radiat Oncol Biol Phys 2009; 73 (3) 789-94