CC BY-NC 4.0 · Arch Plast Surg 2019; 46(05): 470-474
DOI: 10.5999/aps.2018.00829
Case Report

Successful management of absent sternum in an infant using porcine acellular dermal matrix

Department of Plastic and Reconstructive Surgery, Mary Bridge Children’s Hospital & Health Network, MultiCare Health System, Tacoma, WA, USA
,
Muhammand A.K. Nuri
Seattle Children’s and Mary Bridge Children’s Regional Cardiac Surgery Program, Tacoma, WA, USA
› Author Affiliations

Congenital absent sternum is a rare birth defect that requires early intervention for optimal long-term outcomes. Descriptions of the repair of absent sternum are limited to case reports, and no preferred method for management has been described. Herein, we describe the use of porcine acellular dermal matrix to reconstruct the sternum of an infant with sternal infection following attempted repair using synthetic mesh. The patient was a full-term male with trisomy 21, agenesis of corpus callosum, ventricular septal defect, patent ductus arteriosus, right-sided aortic arch, and congenital absence of sternum with no sternal bars. Following removal of the infected synthetic mesh, negative pressure wound therapy with instillation was used to manage the open wound and provide direct antibiotic therapy. When blood Creactive protein levels declined to ≤2 mg/L, the sternum was reconstructed using porcine acellular dermal matrix. At 21 months postoperative, the patient demonstrated no respiratory issues. Physical examination and computed tomography imaging identified good approximation of the clavicular heads and sternal cleft and forward curvature of the ribs. This case illustrates the benefits of negative pressure wound therapy and acellular dermal matrix for the reconstruction of absent sternum in the context of infected sternal surgical site previously repaired with synthetic mesh.

The authors thank Tyler Seick (Mary Bridge Children’s Hospital, Tacoma, WA, USA) for assist of surgery.




Publication History

Received: 10 July 2018

Accepted: 15 December 2018

Article published online:
03 April 2022

© 2019. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)

Thieme Medical Publishers, Inc.
333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

 
  • REFERENCES

  • 1 Torre M, Rapuzzi G, Carlucci M. et al. Phenotypic spectrum and management of sternal cleft: literature review and presentation of a new series. Eur J Cardiothorac Surg 2012; 41: 4-9
  • 2 Sarper A, Oz N, Arslan G. et al. Complete congenital sternal cleft associated with pectus excavatum. Tex Heart Inst J 2002; 29: 206-9
  • 3 Suri RK, Sharma RK, Jha NK. et al. Complete congenital sternal cleft in an adult: repair by autogenous tissues. Ann Thorac Surg 1996; 62: 573-5
  • 4 Kohli V, Nooreyazdan S, Das BN. et al. Surgical reconstruction for absence of sternum and pericardium in a newborn. Indian J Pediatr 2006; 73: 367-8
  • 5 Al-Yamani M, Lavrand F, Thambo JB. et al. Upper sternal cleft with a complex congenital heart defect: repair in a single stage. Ann Thorac Surg 2016; 101: 760-2
  • 6 Olthof PB, Colenbrander DA, Van Der Kuip M. et al. Mesh-repaired complete sternal cleft complicated by multi-resistant bacterial infection. APSP J Case Rep 2014; 5: 30
  • 7 Paton BL, Novitsky YW, Zerey M. et al. Management of infections of polytetrafluoroethylene-based mesh. Surg Infect (Larchmt) 2007; 8: 337-41
  • 8 de Vries Reilingh TS, van Goor H, Charbon JA. et al. Repair of giant midline abdominal wall hernias: “components separation technique” versus prosthetic repair: interim analysis of a randomized controlled trial. World J Surg 2007; 31: 756-63
  • 9 Szczerba SR, Dumanian GA. Definitive surgical treatment of infected or exposed ventral hernia mesh. Ann Surg 2003; 237: 437-41
  • 10 Diaz Jr JJ, Guy J, Berkes MB. et al. Acellular dermal allograft for ventral hernia repair in the compromised surgical field. Am Surg 2006; 72: 1181-7
  • 11 Ventral Hernia Working Group. Breuing K, Butler CE. et al. Incisional ventral hernias: review of the literature and recommendations regarding the grading and technique of repair. Surgery 2010; 148: 544-58
  • 12 Gupta S. Optimal use of negative pressure wound therapy for skin grafts. Int Wound J 2012; 9 Suppl 1: 40-7
  • 13 Atkins BZ, Tetterton JK, Petersen RP. et al. Laser Doppler flowmetry assessment of peristernal perfusion after cardiac surgery: beneficial effect of negative pressure therapy. Int Wound J 2011; 8: 56-62
  • 14 Colli A, Camara ML. First experience with a new negative pressure incision management system on surgical incisions after cardiac surgery in high risk patients. J Cardiothorac Surg 2011; 6: 160
  • 15 Ennker IC, Malkoc A, Pietrowski D. et al. The concept of negative pressure wound therapy (NPWT) after poststernotomy mediastinitis: a single center experience with 54 patients. J Cardiothorac Surg 2009; 4: 5