CC BY-NC 4.0 · Arch Plast Surg 2012; 39(05): 497-503
DOI: 10.5999/aps.2012.39.5.497
Original Article

Reliability of Reconstructed Breast Flap after Chemotherapy and Radiotherapy in Immediate Breast Reconstruction

Keun-Cheol Lee
Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea
,
Tae-Heon Kim
Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea
,
Su-Seong Park
Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea
,
Min-Su Kim
Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea
,
Myung-Hoon Kim
Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea
,
Seok-Kwun Kim
Department of Plastic and Reconstructive Surgery, Dong-A University College of Medicine, Busan, Korea
,
Se-Heon Cho
Department of General Surgery, Dong-A University College of Medicine, Busan, Korea
,
Mi-Ri Lee
Department of General Surgery, Dong-A University College of Medicine, Busan, Korea
,
Jin-Hwa Lee
Department of Radiology, Dong-A University College of Medicine, Busan, Korea
,
Hyung-Sik Lee
Department of Radiation Oncology, Dong-A University College of Medicine, Busan, Korea
,
Dae-Cheol Kim
Department of Pathology, Dong-A University College of Medicine, Busan, Korea
› Author Affiliations
This study was supported by research funds from Dong-A university.

Background Postmastectomy adjuvant therapy is used to prevent locoregional recurrence and improve overall breast cancer specific survival rates. However, it can adversely affect the cosmetic results of reconstruction. Therefore, the authors examined flap stability and patients' satisfaction with immediate breast reconstruction after adjuvant therapy.

Methods We retrospectively reviewed the medical records of 204 patients from January 2006 to November 2011. For complication rates, the authors categorized the patients who underwent the immediate breast reconstruction into 4 groups: adjuvant chemotherapy and radiotherapy group, adjuvant chemotherapy only group, adjuvant radiotherapy only group, and the group that did not undergo adjuvant therapy. For comparison of patients' satisfaction, the study was performed with an additional 16 patients who had undergone delayed breast reconstruction.

Results Regarding complication rates, the group that had undergone adjuvant therapy showed no significant difference compared to the group that did not undergo adjuvant therapy. In evaluating the patients' satisfaction, there was no significant difference.

Conclusions Even after adjuvant therapy, immediate breast reconstruction showed good results with respect to flap stability and patients' satisfaction. Immediate breast reconstruction and adjuvant therapy is a safe and useful option for breast cancer patients.

This study was presented at the 10th Korea-Japan Congress of Plastic and Reconstructive Surgery, on June 16-18, 2010 in Busan, Korea.




Publication History

Received: 01 April 2012

Accepted: 25 July 2012

Article published online:
01 May 2022

© 2012. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)

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  • REFERENCES

  • 1 Alderman AK, Collins ED, Schott A. et al. The impact of breast reconstruction on the delivery of chemotherapy. Cancer 2010; 116: 1791-1800
  • 2 Spear SL, Ducic I, Low M. et al. The effect of radiation on pedicled TRAM flap breast reconstruction: outcomes and implications. Plast Reconstr Surg 2005; 115: 84-95
  • 3 Kronowitz SJ, Robb GL. Radiation therapy and breast reconstruction: a critical review of the literature. Plast Reconstr Surg 2009; 124: 395-408
  • 4 Lee BT, AA T, Colakoglu S. et al. Postmastectomy radiation therapy and breast reconstruction: an analysis of complications and patient satisfaction. Ann Plast Surg 2010; 64: 679-683
  • 5 Jagsi R, Abrahamse P, Morrow M. et al. Postmastectomy radiotherapy for breast cancer: patterns, correlates, communication, and insights into the decision process. Cancer 2009; 115: 1185-1193
  • 6 Paulson RL, Chang FC, Helmer SD. Kansas surgeons' attitudes toward immediate breast reconstruction: a statewide survey. Am J Surg 1994; 168: 543-546
  • 7 Wellisch DK, Schain WS, Noone RB. et al. Psychosocial correlates of immediate versus delayed reconstruction of the breast. Plast Reconstr Surg 1985; 76: 713-718
  • 8 Zhang YJ, Sun GQ, Chen J. et al. Postmastectomy locoregional recurrence and survival in early stage breast cancer patients with one to three axillary lymph node metastases. Ai Zheng 2009; 28: 395-401
  • 9 Buchholz TA, Strom EA, Perkins GH. et al. Controversies regarding the use of radiation after mastectomy in breast cancer. Oncologist 2002; 7: 539-546
  • 10 Yi A, Kim HH, Shin HJ. et al. Radiation-induced complications after breast cancer radiation therapy: a pictorial review of multimodality imaging findings. Korean J Radiol 2009; 10: 496-507
  • 11 Senkus-Konefka E, Jassem J. Complications of breast-cancer radiotherapy. Clin Oncol (R Coll Radiol) 2006; 18: 229-235
  • 12 Senkus-Konefka E, Welnicka-Jaskiewicz M, Jaskiewicz J. et al. Radiotherapy for breast cancer in patients undergoing breast reconstruction or augmentation. Cancer Treat Rev 2004; 30: 671-682