RSS-Feed abonnieren
![](/products/assets/desktop/img/oa-logo.png)
DOI: 10.5935/1984-0063.20200119
Oxygen desaturation index as alternative parameter in screening patients with severe obstructive sleep apnea
![](https://www.thieme-connect.de/media/10.1055-s-00056804/2022S01/lookinside/thumbnails/10-5935-1984-0063-20200119_20200119-1.jpg)
Objectives Assess reliability of oxygen desaturation index (ODI) as an alternative parameter to apnea hypopnea index (AHI) in screening patients with severe obstructive sleep apnea (OSA).
Material and Methods Retrospectively two-year data on demography, anthropometric features, polysomnography (PSG) parameters [AHI, ODI, minimum oxygen saturation (SpO2), mean SpO2], and Epworth sleepiness score (ESS) were collected and analyzed.
Results Study showed significant correlation of ESS with AHI, ODI, apnea-hypopnea percentage of sleep period time (AH%SPT), mean SpO2 and minimum SpO2 with highest correlation being with AHI. A Cohen’s weighted Kappa analysis showed good concordance of 87.32% between AHI and ODI in classifying severity of OSA, with a significant R2 correlation of 0.84 on linear regression. An ODI>20 has a sensitivity of 96.6% and specificity of 69.6% in diagnosing severe OSA.
Conclusion Good concordance between AHI and ODI makes nocturnal oximetry a less expensive tool to confdently screen patients with severe OSA.
FUNDING
This study received no funding.
COMPLIANCE WITH ETHICAL STANDARDS
ETHICAL APPROVAL
All procedures performed in this study were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Institutional review board approval was obtained prior to the commencement of the retrospective study.
INFORMED CONSENT
Since this is a retrospective study using existing data, informed consent was not required.
Publikationsverlauf
Eingereicht: 27. Oktober 2021
Angenommen: 02. März 2021
Artikel online veröffentlicht:
01. Dezember 2023
© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
-
REFERENCES
- 1 Franklin KA, Lindberg E. Obstructive sleep apnea is a common disorder in the population - a review on the epidemiology of sleep apnea. J Thorac Dis. 2015 Aug;7(8):1311-22.
- 2 Engleman HM, Douglas NJ. Sleep 4: sleepiness, cognitive function, and quality of life in obstructive sleep apnoea/ hypopnoea syndrome. Thorax. 2004 Jul;59(7):618-22.
- 3 Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep. 1991 Dec;14(6):540-5.
- 4 Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017 Mar;13(3):479-504.
- 5 Temirbekov D, Güneş S, Yazici ZM, Sayini I. The ignored parameter in the diagnosis of obstructive sleep apnea syndrome: the oxygen desaturation index. Turk Arch Otorhinolaryngol. 2018 Mar;56(1):1-6.
- 6 Chung F, Liao P, Elsaid H, Islam S, Shapiro CM, Sun Y. Oxygen desaturation index from nocturnal oximetry: a sensitive and specific tool to detect sleep-disordered breathing in surgical patients. Anesth Analg. 2012 May;114(5):993-1000.
- 7 Hang LW, Wang HL, Chen JH, Hsu JC, Lin HH, Chung WS, et al. Validation of overnight oximetry to diagnose patients with moderate to severe obstructive sleep apnea. BMC Pulm Med. 2015 Mar;15:24
- 8 Seneviratne U, Puvanendran K. Excessive daytime sleepiness in obstructive sleep apnea: prevalence, severity, and predictors. Sleep Med. 2004 Jul;5(4):339-43.
- 9 Doneh B. Epworth sleepiness scale. Occup Med (Lond). 2015 Aug;65(6):508.
- 10 Hayashida K, Inoue Y, Chiba S, Yagi T, Urashima M, Honda Y, et al. Factors influencing subjective sleepiness in patients with obstructive sleep apnea syndrome. Psychiatry Clin Neurosci. 2007 Sep;61(5):558-63.
- 11 Bausmer U, Gouveris H, Selivanova O, Goepel B, Mann W. Correlation of the Epworth sleepiness scale with respiratory sleep parameters in patients with sleep-related breathing disorders and upper airway pathology. Eur Arch Otorhinolaryngol. 2010 Oct;267(10):1645-8.
- 12 Guilleminault C, Do Kim Y, Chowdhuri S, Horita M, Ohayon M, Kushida C. Sleep and daytime sleepiness in upper airway resistance syndrome compared to obstructive sleep apnoea syndrome. Eur Respir J. 2001 May;17(5):838-47.
- 13 Kapur VK, Baldwin CM, Resnick HE, Gottlieb DJ, Nieto FJ. Sleepiness in patients with moderate to severe sleepdisordered breathing. Sleep. 2005 Apr;28(4):472-7.