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CC BY-NC-ND 4.0 · Sleep Sci 2021; 14(03): 196-200
DOI: 10.5935/1984-0063.20200050
ORIGINAL ARTICLE

The relationship between thyroid function tests and sleep quality: cross-sectional study

Mohammad Reza Nazem
1   Department of Clinical Biochemistry, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.
,
Ehsan Bastanhagh
2   Department of Anesthesiology, Pain and Critical Care, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.
,
Ali Emami
3   Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
,
Mehdi Hedayati
3   Cellular and Molecular Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
,
Saghar Samimi
2   Department of Anesthesiology, Pain and Critical Care, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran.
,
Masoumeh Karami
4   Department of Biochemistry, Medical Faculty, AJA University of Medical Sciences, Tehran, Iran.
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ABSTRACT

Introduction: The relationship between sleep and hormones have long been recognized. Studies indicated that sleep quality is one of the major modulatory effects on the endocrine system. In this study, we aimed to assess the serum concentration of thyroid hormones in individuals who suffered from low quality sleep.

Material and Methods: Based on the Pittsburgh Sleep Quality Index and ISMA Stress questionnaire, we divided 83 participants into two groups. Forty-one individuals with low quality sleep group and 42 with good quality sleep group, all from the male students of a medical school in Tehran, Iran, participated in this descriptive and cross-sectional study. Then, serum levels of thyroid hormones including free T3, free T4, and TSH were assessed and compared between two groups.

Results: There were a significant increase in serum levels of FT4 (p=0.01) and TSH (p=0.02). There were also meaningful correlations between sleep score and stress score (p=0.008) as well as stress score and FT4 (p=0.03) in the case group.

Conclusions: The current study showed that thyroid function tests (T4 and TSH) significantly rose in the poor sleep condition. We also found correlations between sleep score, stress score, and FT4 in the poor sleep condition group that suggest low sleep quality can affect thyroid hormones.

Keywords:

Sleep Deprivation - Triiodothyronine - Thyroxine - Pittsburgh Sleep Quality Index - TSH, T3, T4

FUNDING

There has been no income received from external parties.


INFORMED CONSENT

The participants provided written, informed consent before participating in this research.


DISCLOSURE

The authors declare that they have no conflicts of interest or disclosures to make.




Publication History

Received: 04 April 2019

Accepted: 17 August 2020

Article published online:
30 November 2023

© 2021. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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