CC BY-NC-ND 4.0 · Sleep Sci 2021; 14(01): 77-81
DOI: 10.5935/1984-0063.20200042
Short Communications

Contribution of pulse oximetry in relation to respiratory flow events in a home-based approach aimed at diagnosing obstructive sleep apnea

Eduardo Enrique Borsini
1   Hospital Británico de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.
,
Magali Blanco
1   Hospital Británico de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.
,
Glenda Ernst
1   Hospital Británico de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.
,
Alejandro Salvado
1   Hospital Británico de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.
,
Ignacio Bledel
2   Hospital Alemán de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.
,
Carlos Alberto Nigro
2   Hospital Alemán de Buenos Aires, Sleep - Buenos Aires - Capital Federal - Argentina.
› Author Affiliations

Objective To compare pulse oximetry with manual analysis against all signals of respiratory polygraphy.

Material and Methods This retrospective study estimated sensitivity (S), specificity (Sp) and positive/negative likelihood ratio (LR+/-) of the oxygen desaturation index (ODI-test) and apnea-hypopnea index (AHI-reference).

Results 3854 patients (61.5% men) were included. Age, BMI, Epworth sleepiness scale and AHI were: 55 years (44-65), 30.9kg/m2 (27-36), 7 points (4-11), and 14 events/hour (6-25), respectively. 18% showed an AHI <5 events/hour, 34% = 5 and <15, 27% = or > 15 and < 30, and 31% > 30. The S, Sp, and LR+/- of ODI for AHI = 5 events/hour was 93%, 92%, 12 and 0.08 with an accuracy of 93%. For AHI = 15 events/hour, the values were: S 94%, Sp 94%, LR+ 15 and LR- 0.06 and 94% accuracy (r(2) Spearman: 0.92).

Conclusion In a population at a high risk for OSA, home-based pulse oximetry had a diagnostic accuracy > 90% when is compared against all respiratory signals obtained from simplified home sleep testing.



Publication History

Received: 08 February 2020

Accepted: 01 August 2020

Article published online:
30 November 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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  • REFERENCES

  • 1 Phillipson EA. Sleep apnea - a mayor public health problem. N Engl J Med. 1993 Apr;328(17):1271-3.
  • 2 Loke YK, Brown JW, Kwok CS, Niruban A, Myint PK. Association of obstructive sleep apnea with risk of serious cardiovascular events: a systematic review and meta-analysis. Circ Cardiovasc Qual Outcomes. 2012 Sep;5(5):720-8.
  • 3 Durgan DJ, Bryan Junior RM. Cerebrovascular consequences of obstructive sleep apnea. J Am Heart Assoc. 2012 Aug;1(4):e000091.
  • 4 Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep disorders breathing among middle-aged adults. N Engl J Med. 1993 Apr;328(17):1230-6.
  • 5 Tufik S, Santos-Silva R, Taddei JA, Bittencourt LR. Obstructive sleep apnea syndrome in the Sao Paulo epidemiologic sleep study. Sleep Med. 2010 May;11(5):441-6.
  • 6 Benjafield AV, Ayas NT, Eastwood PR, Heinzer R, Ip MSM, Morrell MJ, et al. Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis. Lancet Respir Med. 2019 Aug;7(8):687-98.
  • 7 Grupo Español de Sueño (GES). Documento consenso español sobre el síndrome de apneas-hipopneas del sueño. Arch Bronconeumol. 2005;41(Suppl 4):81-101.
  • 8 Collop NA, Anderson WM, Boehlecke B, Claman D, Goldberg R, Gottlieb DJ, et al. Clinical guidelines for the use of unattended portable monitors in the diagnosis of obstructive sleep apnea in adult patients. Portable Monitoring Task Force of the American Academy of Sleep Medicine. J Clin Sleep Med. 2007;3(7):737-47.
  • 9 Berry RB, Budhiraja R, Gottlieb DJ, Gozal D, Iber C, Kapur VK, et al. Rules for scoring respiratory events in sleep: update of the 2007 AASM manual for the scoring of sleep and associated events. J Clin Sleep Med. 2012;8(5):597-619.
  • 10 Ernst G, Bosio M, Salvado A, Nogueira F, Nigro C, Borsini E. Comparative study between sequential automatic and manual home respiratory polygraphy scoring using a three-channel device: impact of the manual editing of events to identify severe obstructive sleep apnea. Sleep Disord. 2015;314534.
  • 11 Ernst G, Bosio M, Salvado A, Dibur E, Nigro C, Borsini E. Difference between apnea-hypopnea index (AHI) and oxygen desaturation index (ODI): proportional increase associated with degree of obesity. Sleep Breath. 2016 Dec;20(4):1175-83.
  • 12 Borsini E, Blanco M, Bosio M, Fernando DT, Ernst G, Salvado A. “Diagnosis of sleep apnea in network” respiratory polygraphy as a decentralization strategy. Sleep Sci. 2016 Jul/Sep;9(3):244-8.
  • 13 Fabius TM, Benistant JR, Bekkedam L, van der Palen J, Jongh FHC, Eijsvogel MMM. Validation of the oxygen desaturation index in the diagnostic workup of obstructive sleep apnea. Sleep Breath. 2019;23(1):57-63.
  • 14 Dawson A, Loving RT, Gordon RM, Abel SL, Loewy D, Kripke DF, et al. Type III home sleep testing versus pulse oximetry: is the respiratory disturbance index better than the oxygen desaturation index to predict the apnoea-hypopnoea index measured during laboratory polysomnography?. BMJ Open. 2015;5(6):e007956.
  • 15 Chai-Coetzer CL, Antic NA, Hamilton GS, McArdle N, Wong K, Yee BJ, et al. Physician decision making and clinical outcomes with laboratory polysomnography or limited channel sleep studies for obstructive sleep apnea: a randomized trial. Ann Intern Med. 2017;166(5):332-40.
  • 16 Corral J, Sánchez-Quiroga MÁ, Carmona-Bernal C, Sánchez- Armengol Á, de la Torre AS, Durán-Cantolla J, et al. Spanish Sleep Network. Conventional polysomnography is not necessary for the management of most patients with suspected obstructive sleep apnea. Noninferiority, randomized controlled trial. Am J Respir Crit Care Med. 2017;196:1181-90.
  • 17 Nogueira F, Nigro C, Cambursano H, Borsini E, Silio J, Avila J. Practical guidelines for the diagnosis and treatment of obstructive sleep apnea syndrome. Medicina (B Aires). 2013;73(4):349-62.
  • 18 Deviaene M, Testelmans D, Buyse B, Borzée P, Van Huffel S, Varon C. Automatic screening of sleep apnea patients based on the SpO2 signal. IEEE. 2018;23(2):607-17.
  • 19 Nigro CA, Borsini EE, Dibur E, Larrateguy LD, Cazaux A, Elias C, et al. CPAP indication based on clinical data and oximetry for patients with suspicion of obstructive sleep apnea: a multicenter trial. Sleep Sci. 2019;12(4):249. DOI: https://doi.org/10.5935/1984-0063.20190089
  • 20 Kapur VK, Auckley DH, Chowdhuri S, Kuhlmann DC, Mehra R, Ramar K, et al. Clinical practice guideline for diagnostic testing for adult obstructive sleep apnea: an American Academy of Sleep Medicine Clinical Practice Guideline. J Clin Sleep Med. 2017 Mar;13(3):479-504.