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CC BY-NC-ND 4.0 · Sleep Sci 2020; 13(02): 172-175
DOI: 10.5935/1984-0063.20190139
SHORT COMMUNICATION

Sleep quality in children with atopic dermatitis during flares and after treatment

Daniela Kahn
1   Pontificia Universidad Catolica de Chile, Division of Pediatrics, School of Medicine - Santiago - Metropolitana - Chile.
,
Carolina Iturriaga
2   Pontificia Universidad Católica de Chile, Santiago, Chile., Department of Pediatric Infectious Diseases and Immunology - Santiagio - Metropolitana - Chile.
,
Katalina Bertran
3   Clinica Alemana Santiago UDD, Pediatrics - Santiago - Metropolitana - Chile.
,
Ignacio Fernandez
4   Centro de Estudios para el Desarrollo, Desarrollo - Santiago - Metropolitana - Chile.
,
Guillermo Perez-Mateluna
2   Pontificia Universidad Católica de Chile, Santiago, Chile., Department of Pediatric Infectious Diseases and Immunology - Santiagio - Metropolitana - Chile.
,
Arturo Borzutzky
2   Pontificia Universidad Católica de Chile, Santiago, Chile., Department of Pediatric Infectious Diseases and Immunology - Santiagio - Metropolitana - Chile.
,
Pablo E. Brockmann
5   Pontificia Universidad Catolica de Chile, Pediatric Sleep Center-Department Pediatric Cardiology and Pulmonology - Santiago - Metropolitana - Chile.
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ABSTRACT

Background: Little is known on sleep quality of children with atopic dermtitis (AD) during flares and how treatment impacts their sleep. The purpose of this study is to evaluate variations in sleep quality of children with AD during flares and its response to intensified treatment.

Material and Methods: Prospective case-crossover study in 10 children with moderate-severe AD. At baseline, AD severity was assessed using SCORAD and patients were prescribed intensified AD therapy. All subjects were monitored by actigraphy during 14 days and returned for SCORAD assessment.

Results: Subjects’ age was 5.6 ± 5.3 years; 50% were female. Sleep duration was decreased in all subjects and awakenings were increased in 90%. Parental perception of sleep significantly differed from actigraphy results: parents estimated less sleep duration and less awakenings. Nocturnal sleep efficiency at baseline was reduced in 50%. After intensified treatment, median SCORAD decreased from 58.5 to 31.3 (p=0.005), with significant improvement in sleep loss and pruritus visual analogue scales. Despite improvement of SCORAD and parental perception of sleep loss and pruritus, objective sleep duration and efficiency measured by actigraphy did not vary significantly after intensified treatment. Change in SCORAD, sleep loss and pruritus scales did not correlate significantly with change in sleep duration, efficiency or other actigraphic sleep quality measurements.

Conclusions: Children with moderate-severe AD have sleep quality abnormalities, with decreased sleep duration, low sleep efficiency and increased awakenings. Improvement in AD severity upon intensified AD treatment was associated with improved parental perception of sleep loss, but not of objective sleep quality assessed by actigraphy.

Keywords:

Atopic Dermatitis - Sleep - Sleep Efficiency - Awakenings - Actigraphy


Publication History

Received: 18 October 2019

Accepted: 19 December 2019

Article published online:
09 November 2023

© 2023. Brazilian Sleep Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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